Antagonists
Mostrando 13-24 de 1774 artigos, teses e dissertações.
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13. Endophytic fungi from Brachiaria grasses in Brazil and preliminary screening of Sclerotinia sclerotiorum antagonists
ABSTRACT: Fungal endophytes of Brachiaria, a nonhost of Sclerotinia sclerotiorum, may harbor species with antagonistic effects against this plant pathogen. The objective of this work was to investigate the diversity of endophytic fungi associated with different Brachiaria species and hybrids and evaluate their potential to inhibit the plant pathogen S. scler
Sci. agric. (Piracicaba, Braz.). Publicado em: 05/09/2019
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14. CYTOTOXIC EFFECTS OF ARIPIPRAZOLE ON MKN45 AND NIH3T3 CELL LINES AND GENOTOXIC EFFECTS ON HUMAN PERIPHERAL BLOOD LYMPHOCYTES
RESUMO CONTEXTO: O câncer gástrico é conhecido como o quarto câncer mais comum. Os tratamentos atuais para o câncer danificaram os tecidos sensíveis do corpo saudável e, em muitos casos, o cancro será recorrente. Portanto, a necessidade de tratamentos que são mais eficazes é desejada. Recentemente, os pesquisadores mudaram sua atenção para os a
Arq. Gastroenterol.. Publicado em: 26/08/2019
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15. HISTORICAL PERSPECTIVE OF GASTROESOPHAGEAL REFLUX DISEASE CLINICAL TREATMENT
RESUMO CONTEXTO: A doença do refluxo gastroesofágico (DRGE) é uma das doenças gastrointestinais mais prevalentes, resultando em limitações significativas na qualidade de vida dos pacientes e, também, relevante utilização de recursos médicos. Um melhor entendimento da fisiopatologia da doença nas últimas cinco décadas tem favorecido a evoluçã
Arq. Gastroenterol.. Publicado em: 26/08/2019
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16. Cannabinoid receptor-1 antagonism: a new perspective on treating a murine schistosomal liver fibrosis model
BACKGROUND Formation of schistosomal granulomata surrounding the ova can result in schistosomiasis-associated liver fibrosis (SSLF). The current standard of treatment is praziquantel (PZQ), which cannot effectively reverse SSLF. The role of the cannabinoid (CB) receptor family in liver fibrosis has recently been highlighted. OBJECTIVES This study aimed t
Mem. Inst. Oswaldo Cruz. Publicado em: 05/08/2019
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17. Galectin 3: an extraordinary multifunctional protein in dermatology. Current knowledge and perspectives
Abstract: Galectin 3 is a unique ~31 kDa protein that recognizes the N-acetyl-lactosamine structure of several glycoconjugates. It mainly occurs in epithelial and myeloid cells, but is also found in a variety of human cell types. In view of the crucial role played by galectin 3 in the regulation of cellular processes of essential importance and in the pathog
An. Bras. Dermatol.. Publicado em: 29/07/2019
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18. Stroke and transient ischemic attacks related to antiplatelet or warfarin interruption
RESUMO Pacientes em terapia anticoagulante ou antiagregante plaquetária frequentemente são solicitados a descontinuar essas medicações antes e durante procedimentos cirúrgicos ou invasivos. Se o paciente interromper tratamento sem supervisão médica, poderá aumentar de risco de acidente vascular cerebral (AVC). Objetivo Identificar prevalência de A
Arq. Neuro-Psiquiatr.. Publicado em: 29/07/2019
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19. Análise do grau de recanalização da trombose venosa profunda: estudo comparativo de pacientes tratados com varfarina versus rivaroxabana
Resumo Contexto A trombose venosa profunda (TVP) afeta anualmente cerca de dez milhões de pessoas no mundo e tem como principais complicações a embolia pulmonar e a síndrome pós-trombótica. O tratamento padrão é a anticoagulação, que pode ser realizada com heparinas, antagonistas da vitamina K, fondaparinux ou, mais recentemente, com anticoagulant
J. vasc. bras.. Publicado em: 27/06/2019
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20. Risk factors associated with in-hospital falls reported to the Patient Safety Commitee of a teaching hospital
RESUMO Objetivo Investigar o uso de medicamentos que aumentam o risco de queda entre pacientes que tiveram quedas notificadas ao Núcleo de Segurança do Paciente de um hospital, bem como identificar os fatores associados ao risco elevado de queda. Métodos Trata-se de estudo transversal realizado em hospital de ensino. A população do estudo foi compos
Einstein (São Paulo). Publicado em: 14/02/2019
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21. Antidiarrheal effect of extract from the bark of Combretum leprosum in mice
Abstract This study investigated the effects of the ethanolic extract from the bark of Combretum leprosum (ECL) on intestinal transit and castor-oil induced diarrhea in mice. The oral administration of ECL (750 and 1000 mg/kg) slowed intestinal transit (ID50 of 455 mg/kg). The ECL (250-1000 mg/kg) reduced castor-oil induced diarrhea, in a time- and dose-depe
An. Acad. Bras. Ciênc.. Publicado em: 17/12/2018
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22. Participation of hepatic α/β-adrenoceptors and AT1 receptors in glucose release and portal hypertensive response induced by adrenaline or angiotensin II
It has been previously demonstrated that the hemodynamic effect induced by angiotensin II (AII) in the liver was completely abolished by losartan while glucose release was partially affected by losartan. Angiotensin II type 1 (AT1) and adrenergic (∝1- and β-) receptors (AR) belong to the G-proteins superfamily, which signaling promote glycogen breakdown a
Braz J Med Biol Res. Publicado em: 14/11/2018
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23. Platelet activating factor receptor antagonists improve the efficacy of experimental chemo- and radiotherapy
Platelet activating factor is a lipid mediator of inflammation, and in recent decades, it has emerged as an important factor in tumor outcomes. Platelet activating factor acts by specific binding to its receptor, which is present in both tumor cells and cells that infiltrate tumors. Pro-tumorigenic effects of platelet activating factor receptor in tumors inc
Clinics. Publicado em: 11/10/2018
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24. Insulin Substrate Receptor (IRS) proteins in normal and malignant hematopoiesis
The insulin receptor substrate (IRS) proteins are a family of cytoplasmic proteins that integrate and coordinate the transmission of signals from the extracellular to the intracellular environment via transmembrane receptors, thus regulating cell growth, metabolism, survival and proliferation. The PI3K/AKT/mTOR and MAPK signaling pathways are the best-charac
Clinics. Publicado em: 11/10/2018