Alveolar Macrophages
Mostrando 1-12 de 750 artigos, teses e dissertações.
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1. Mesenchymal Stromal Cells Modulate PAF-stimulated Equine Alveolar Macrophages
Abstract Platelet-activating factor (PAF) is a potent proinflammatory mediator that is produced in increased amounts in the lungs of asthmatic humans and horses. The present pilot study, shows that mesenchymal stromal cells can modulate alveolar macrophage function in asthma, interfering in the activity of PAF, being another potential pathway for mesenchyma
Braz. arch. biol. technol.. Publicado em: 25/11/2019
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2. Variability in the virulence of specific Mycobacterium tuberculosis clinical isolates alters the capacity of human dendritic cells to signal for T cells
BACKGROUND Once in the pulmonary alveoli, Mycobacterium tuberculosis (Mtb) enters into contact with alveolar macrophages and dendritic cells (DCs). DCs represent the link between the innate and adaptive immune system owing to their capacity to be both a sentinel and an orchestrator of the antigen-specific immune responses against Mtb. The effect that the v
Mem. Inst. Oswaldo Cruz. Publicado em: 12/08/2019
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3. Increased leishmanicidal activity of alveolar macrophages from mature horses with mild equine asthma
RESUMO Os macrófagos alveolares (MAs) são uma parte essencial dos mecanismos de defesa dentro dos pulmões e sua atividade fagocítica é importante para a homeostase desse órgão. A capacidade fagocitária dos MAs obtidos do lavado broncoalveolar de 17 equinos adultos, sem raça definida (oito saudáveis e nove com diagnóstico de asma equina leve), foi
Arq. Bras. Med. Vet. Zootec.. Publicado em: 14/06/2019
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4. Relationships between phagocytosis, mucoid phenotype, and genetic characteristics of Klebsiella pneumoniae clinical isolates
Abstract INTRODUCTION The relationships between phagocytosis, and mucoid phenotype, plasmid profile and virulence, and resistance genetic characteristics of Klebsiella pneumoniae clinical isolates were evaluated. METHODS Thirty isolates were used to determine the mucoid aspect. Four were selected for analysis of phagocytosis by alveolar macrophages. RES
Rev. Soc. Bras. Med. Trop.. Publicado em: 25/04/2019
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5. Clinical and pathological aspects of idiopathic pulmonary fibrosis in cats
RESUMO: As enfermidades pulmonares intersticiais são um grupo de doenças difusas do parênquima pulmonar, nas quais a fibrose pulmonar está incluída. O objetivo deste trabalho é caracterizar os achados clínicos e patológicos da fibrose pulmonar idiopática em três gatas, e avaliar possíveis agentes etiológicos através dos exames bacteriológicos,
Pesq. Vet. Bras.. Publicado em: 2019-02
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6. Saquinavir plus methylprednisolone ameliorates experimental acute lung injury
Glucocorticoid insensitivity is an important barrier to the treatment of several inflammatory diseases, including acute lung injury (ALI). Saquinavir (SQV) is an inhibitor of the human immunodeficiency virus protease, and the therapeutic effects of SQV in ALI accompanied with glucocorticoid insensitivity have not been previously investigated. In this study,
Braz J Med Biol Res. Publicado em: 06/08/2018
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7. The role of bradykinin in lung ischemia-reperfusion injury in a rat lung transplantation model
ABSTRACT PURPOSE: To investigate the role of bradykinin in a rat lung transplantation (LTx) model and preliminarily discuss the relationship between bradykinin and CD26/DPP-4. METHODS: Rats were randomly divided into four groups: Control (CON), Sham, low potassium dextranglucose (LPD), and AB192 (n=15/group). Orthotopic single LTx was performed in the LPD
Acta Cir. Bras.. Publicado em: 2016-12
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8. Evolution of invasive pulmonary aspergillosis produced in mice treated with monoclonal antibodies anti GR-1/Ly-6G and infected with Aspergillus fumigatus strains which presented distincts patterns of production of elastase. / Evolução da aspergilose pulmonar invasiva produzida em camundongos tratados com anticorpos monoclonais anti GR-1/Ly-6G e infectados com amostras de Aspergillus fumigatus que apresentaram distintos padrões de produção de elastase
Invasive Pulmonary Aspergillosis (IPA) is an opportunistic fungal disease, caused mainly by Aspergillus fumigatus, that affects immunocompromised patients. To better understand this mycoses, we originally established in C57BL/6 mice an experimental model of neutrophils depletion by intraperitoneal inoculation of antibodies anti GR-1/Ly-6G, confirmed by total
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 02/04/2012
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9. Efeitos da exposição in vivo à hidroquinona sobre funções do tecido traqueal e de macrófagos alveolares de camundongos / Effects of in vivo hydroquinone exposure on functions of alveolar macrophages and tracheal tissue in mice
A hidroquinona (HQ) é um composto fenólico de origem natural ou antropogênica, encontrada em grandes concentrações no cigarro, além de ser produto da biotransformação do benzeno. Nosso grupo de pesquisa tem demonstrado que a exposição à HQ compromete a resposta inflamatória in vivo. Dando continuidade a estas investigações, este trabalho visou
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 08/04/2011
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10. Pathological and ultrastructural analysis of surgical lung biopsies in patients with swine-origin influenza type A/H1N1 and acute respiratory failure
BACKGROUND: Cases of H1N1 and other pulmonary infections evolve to acute respiratory failure and death when co-infections or lung injury predominate over the immune response, thus requiring early diagnosis to improve treatment. OBJECTIVE: To perform a detailed histopathological analysis of the open lung biopsy specimens from five patients with ARDS with conf
Clinics. Publicado em: 2010
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11. FunÃÃo microbicida de macrÃfagos alveolares de ratos submetidos à desnutriÃÃo neonatal: estudo da infecÃÃo celular, in vitro, por Staphylococcus aureus meticilina sensÃvel e meticilina resistente
Staphylococcus aureus resistant to methicillin have increased significantly in recent years, and is a major public health problem, like is malnutrition, still presents in our country. Therefore it is important to evaluate effects of malnutrition in the neonatal immune response against potential pathogens such as S. aureus. Male Wistar rats were breastfed by
Publicado em: 2009
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12. Role of leukotrienes in phagocytosis via FcgR by alveolar macrophages from healthy and diabetic rats. / Papel dos leucotrienos na fagocitose via FcgR por macrofágos alveolares de ratos sadios e diabéticos.
Avaliamos o papel dos leucotrienos (LTs), as vias de sinalização e o efeito da insulina na fagocitose via FcgR por macrófagos alveolares (MAs) de ratos sadios (RS) e diabéticos (RD). Vimos que a) MAs de RD fagocitam menos que os de RS; b) a fagocitose é dependente de LTs endógenos em RS mas não em RD; c) a adição de LTB4 ou LTD4 aos MAs em cultura a
Publicado em: 2009