Mesenchymal Stromal Cells Modulate PAF-stimulated Equine Alveolar Macrophages
AUTOR(ES)
Michelotto, Pedro Vicente
FONTE
Braz. arch. biol. technol.
DATA DE PUBLICAÇÃO
25/11/2019
RESUMO
Abstract Platelet-activating factor (PAF) is a potent proinflammatory mediator that is produced in increased amounts in the lungs of asthmatic humans and horses. The present pilot study, shows that mesenchymal stromal cells can modulate alveolar macrophage function in asthma, interfering in the activity of PAF, being another potential pathway for mesenchymal stromal cells benefits in asthma.
Documentos Relacionados
- Unilamellar liposomes modulate secretion of tumor necrosis factor by lipopolysaccharide-stimulated macrophages.
- Isolation and characterization of mesenchymal stem/stromal cells from Ctenomys minutus
- Glucocorticoid sensitivity of lipopolysaccharide-stimulated chronic obstructive pulmonary disease alveolar macrophages
- Increased leishmanicidal activity of alveolar macrophages from mature horses with mild equine asthma
- 5-Azacytidine restores interleukin 6-increased production in mesenchymal stromal cells from myelodysplastic patients