3 Animal Models
Mostrando 13-24 de 489 artigos, teses e dissertações.
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13. Preliminary molecular characterization of a proinflammatory and nociceptive molecule from the Echinometra lucunter spines extracts
Abstract Background Sea urchins are animals commonly found on the Brazilian shoreline, being Echinometra lucunter the most abundant species. Accidents caused by E. lucunter have been reported as one of the most frequent in Brazil, and are characterized by intense pain and inflammation, consequence of spine puncture in the skin. In order to characterize suc
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 21/11/2017
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14. Effects of N-acetylcysteine on spinal cord oxidative stress biomarkers in rats with neuropathic pain
N-acetylcysteine (NAC) inhibits nociceptive transmission. This effect has been associated partly with its antioxidant properties. However, the effect of NAC on the levels of lipid hydroperoxides (a pro-oxidant marker), content of ascorbic acid (a key antioxidant molecule of nervous tissue) and total antioxidant capacity (TAC) is unknown. Thus, our study asse
Braz J Med Biol Res. Publicado em: 19/10/2017
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15. Agreement, correlation, and kinetics of the alveolar bone-loss measurement methodologies in a ligature-induced periodontitis animal model
Abstract Periodontal research involves the use of animal models to better understand the biological processes of periodontal diseases and the potential of new or existing therapies. Currently, ligature-induced periodontitis in rats is the main model used in periodontal research, in this model, alveolar bone loss (ABL) is the main parameter evaluated by radio
J. Appl. Oral Sci.. Publicado em: 2017-10
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16. Penile alterations at early stage of type 1 diabetes in rats
ABSTRACT Objective Diabetes affects the erectile function significantly. However, the penile alterations in the early stage of diabetes in experimental animal models have not been well studied. We examined the changes of the penis and its main erectile components in diabetic rats. Materials and methods Male Sprague-Dawley rats were divided into 2 groups:
Int. braz j urol.. Publicado em: 2017-08
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17. IL-10 down-regulates the expression of survival associated gene hspX of Mycobacterium tuberculosis in murine macrophage
Abstract Mycobacterium tuberculosis (MTB) adopts a special survival strategy to overcome the killing mechanism(s) of host immune system. Amongst the many known factors, small heat shock protein 16.3 (sHSP16.3) of MTB encoded by gene hspX has been reported to be critical for the survival of MTB. In the present study, the effect of recombinant murine interfero
Braz J Infect Dis. Publicado em: 2017-08
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18. Accuracy and reliability of a videogrammetry system in the analysis of displacement of Wistar rats
Abstract Aims The behavior of laboratory animals has been studied through displacement, with different objectives by researchers. Methods Although different methods have already been used in the tracking of laboratory animals, manual tracking mode videogrammetry for 2D analysis of displacement has not been observed in animal studies. The aim of this study
Motriz: rev. educ. fis.. Publicado em: 27/07/2017
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19. Osteointegration of porous absorbable bone substitutes: A systematic review of the literature
Biomaterials’ structural characteristics and the addition of osteoinductors influence the osteointegration capacity of bone substitutes. This study aims to identify the characteristics of porous and resorbable bone substitutes that influence new bone formation. An Internet search for studies reporting new bone formation rates in bone defects filled with po
Clinics. Publicado em: 2017-07
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20. Crude glycerin in anaerobic co-digestion of dairy cattle manure increases methane production
ABSTRACT Anaerobic digestion of crude glycerin (CG) along with animal waste has been an excellent option for increasing the production of biogas and methane to achieve efficiency in the treatment of both residues. This study aimed to evaluate improvements in specific productions of biogas and methane, reductions in solid and fibrous components in substrates
Sci. agric. (Piracicaba, Braz.). Publicado em: 2017-06
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21. Development of a mouse computational model for MCNPx based on Digimouse (r) images and dosimetric assays
ABSTRACT The aim of this study was to create and test a new mice 3D-voxel phantom named DM_BRA for mice and human first-estimation radiopharmaceutical dosimetry. Previously, the article reviews the state-of-art in animal model development. Images from Digimouse CT database were used in the segmentation and on the generation of the voxelized phantom. Simulati
Braz. J. Pharm. Sci.. Publicado em: 20/04/2017
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22. Natural Compounds from Mexican Medicinal Plants as Potential Drug Leads for Anti-Tuberculosis Drugs
ABSTRACT In Mexican Traditional Medicine 187 plant species are used in the treatment of respiratory conditions that may be associated with tuberculosis. In this contribution, we review the ethnobotany, chemistry and pharmacology of 63 species whose extracts have been assayed for antimycobacterial activity in vitro. Among these, the most potent is Aristolochi
An. Acad. Bras. Ciênc.. Publicado em: 09/02/2017
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23. Linear Programming in the economic estimate of livestock-crop integration: application to a Brazilian dairy farm
ABSTRACT A linear programming mathematical model was applied to a representative dairy farm located in Brazil. The results showed that optimization models are relevant tools to assist in the planning and management of agricultural production, as well as to assist in estimating potential gains from the use of integrated systems. Diversification was a necessar
R. Bras. Zootec.. Publicado em: 2016-04
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24. Specific training for LESS surgery results from a prospective study in the animal model
ABSTRACT Objective to prospectively evaluate the ability of post-graduate students enrolled in a laparoscopy program of the Institute for Teaching and Research to complete single port total nephrectomies. Materials and Methods 15 post-graduate students were enrolled in the study, which was performed using the SILStm port system for single-port procedures
Int. braz j urol.. Publicado em: 2016-02