2 Flowability
Mostrando 1-12 de 14 artigos, teses e dissertações.
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1. Solid dispersion-based pellet for colon delivery of tacrolimus through time- and pH-dependent layer coating: preparation, in vitro and in vivo studies
The intent of the present investigation is to develop and evaluate colon-specific coated tacrolimus solid dispersion pellet (SDP) that retards drug release in the stomach and small intestine but progressively releases in the colon. Tacrolimus-SDP was prepared by extrusion-spheronization technology and optimized by the micromeritic properties including flowab
Braz. J. Pharm. Sci.. Publicado em: 24/10/2019
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2. Determination of the optimal replacement content of Portland cement by stone powder using particle packing methods and analysis of the influence of the excess water on the consistency of pastes
Resumo O cimento Portland é considerado o componente de base com o maior impacto ambiental na construção civil, em termos de emissões de CO2. Quanto aos agregados, o processo de cominuição das rochas, além da areia artificial, gera pó de pedra que acaba sendo armazenado ao ar livre, gerando impactos ambientais. Assim, a substituição do cimento por
Rev. IBRACON Estrut. Mater.. Publicado em: 20/05/2019
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3. Physical properties and biological effects of mineral trioxide aggregate mixed with methylcellulose and calcium chloride
Abstract Objectives: Methylcellulose (MC) is a chemical compound derived from cellulose. MTA mixed with MC reduces setting time and increases plasticity. This study assessed the influence of MC as an anti-washout ingredient and CaCl2 as a setting time accelerator on the physical and biological properties of MTA. Material and Methods: Test materials were di
J. Appl. Oral Sci.. Publicado em: 2017-12
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4. Assessment of radio frequency heating on composition, microstructure, flowability and rehydration characteristics of milk powder
Abstract Radio frequency heating (RFH) provides higher efficiency and more uniform heating zone compared with conventional method. The aim of present work is to evaluate the effect of RFH (at 90 °C for 5 or 10 min) on the changes in composition (protein oxidation and fat distribution), microstructure, flow characteristic and rehydration property of infant m
Food Sci. Technol. Publicado em: 30/10/2017
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5. Engineering spray-dried rosemary extracts with improved physicomechanical properties: a design of experiments issue
ABSTRACT A 33 Box–Behnken design and Response Surface Methodology were performed to evaluate the influence of extract feed rate, drying air inlet temperature and spray nozzle airflow rate on the process yield, stability parameters (moisture content and water activity) and on several physicomechanical properties of spray-dried rosemary extracts. Powder yiel
Rev. bras. farmacogn.. Publicado em: 2017-04
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6. Bioactivity, physical and chemical properties of MTA mixed with propylene glycol
AbstractObjective To investigate the physical (setting time, hardness, flowability, microstructure) and chemical (pH change, calcium release, crystallinity) properties and the biological outcomes (cell survival and differentiation) of mineral trioxide aggregate (MTA) mixed using different proportions of propylene glycol (PG) and water.Material and Methods Wh
J. Appl. Oral Sci.. Publicado em: 2015-08
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7. Caracterização de biomassas brasileiras para fins de aproveitamento energético / Characterization of brazilian biomasses for energy recovery
New energetic alternatives have been the subject of discussion about conservation of natural resources. Such discourses are based mainly on reducing emissions of greenhouse gases and other pollutants, caused mostly by the use of fossil fuels, major source of energy today. In view of the applicability of biomass as energy input, this paper presents an experim
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 29/02/2012
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8. Study of pre-formulation, pharmaceutical development and characterization of solid dosage forms of olanzapine / Estudo de pré-formulação, desenvolvimento farmacotécnico e caracterização de formas farmacêuticas sólidas da olanzapina
Among manufacturing processes available, direct compression is indicated for OLZ because this drug is moisture sensitive. Before drug developement, preformulation investigations involving physical and chemical properties of drug and excipient combined and separated must be performed. Thus, drug solubility profile, thermal analysis techniques, mainly DSC and
Publicado em: 2010
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9. Study of Fluidized Bed Hot Melt Granulation using solid Dispersion of Indomethacin / Estudo da granulação por solidificação de materiais fundidos em leito fluidizado utilizando dispersão sólida de indometacina
Recently, there is a renewed interest in the fluidized bed hot melt granulation for the preparation of solid dosage forms in the pharmaceutical industry and academy. The several advantages of this technique have attracted may researchers, but the main advantage are undoubtedly the solvent free operation and the short processing times. The aim of this work wa
Publicado em: 2009
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10. Evaluation of the influence of drying aid on the atomized cashew juice properties / AvaliaÃÃo da influÃncia de adjuvantes de secagem sobre as propriedades de suco de caju atomizado
The fruit industries have been compelled to adapt to the increasing consumer requeriments related to convenience, food safety and health benefits. An evidence of such changes is the increasing production of fruit juices and related products. Although the ready-to-drink fruit nectars are convenience products, they have high weight and volume, since they have
Publicado em: 2008
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11. Influência da Natureza do Fosfato de Cálcio Dibásico Anidro na Qualidade de uma Forma Farmacêutica Sólida Manufaturada via Granulação Seca / Impact of the nature of anhydrous dibasic calcium phosphate on the quality of a pharmaceutical solid dosage form manufactured through dry granulation;
No presente trabalho foi estudado o impacto da natureza do fosfato de cálcio dibásico anidro (ADCP) na qualidade de uma forma farmacêutica sólida, denominada medicamento, manufaturada via granulação seca. O ADCP é uma das cinco matérias-primas que constituem o medicamento; Inicialmente, foi avaliada a natureza dos dois ADCPs estudados, aqui denominad
Publicado em: 2005
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12. A new method to predict flowability using a microscale fluid bed
The purpose of this research was to develop a new method to predict the flow behavior of pharmaceutical powders using a multichamber microscale fluid bed. Different amounts of poorly flowing paracetamol were added to various grades of microcrystalline celluloses and silicified microcrystalline cellulose powders. Magnesium stearate was used as a lubricant. Ex
Springer-Verlag.