Virus Transport
Mostrando 1-12 de 1070 artigos, teses e dissertações.
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1. Desenvolvimento de vetores não virais para entrega gênica baseados na cadeia leve de dineína Rp3 = : Development of non viral vectors for gene delivery based on dynein light chain Rp3 / Development of non viral vectors for gene delivery based on dynein light chain Rp3
Gene delivery is a promising technique with great medical potential that consists in the introduction of exogenous nucleic acids, and can be applied for gene therapy as well as DNA vaccination. However, its use is still limited by the lack of an ideal delivery vector, which is both safe and efficient. Although much more effective, viral vectors still raise s
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 11/07/2012
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2. Identificação de um fator do hospedeiro, RPS5A, envolvido na interação com a proteína de movimento (MP) de geminivírus / Identification of movement protein MP-intaracting host facotrs
The movement protein MP from bipartite geminivirus (begomovirus) facilitates the cell-to-cell and long-distance transport of viral DNA in addition to affecting viral pathogenicity. To identify host factors that interact with MP, initially a cDNA library prepared from CaLCuV (Cabbage leaf curl virus)-infected Arabidopsis leaf mRNA was generated in a pEXPAD502
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 18/02/2011
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3. Gene expression promoted by the SV40 DNA targeting sequence and the hypoxia-responsive element under normoxia and hypoxia
The main objective of the present study was to find suitable DNA-targeting sequences (DTS) for the construction of plasmid vectors to be used to treat ischemic diseases. The well-known Simian virus 40 nuclear DTS (SV40-DTS) and hypoxia-responsive element (HRE) sequences were used to construct plasmid vectors to express the human vascular endothelial growth f
Brazilian Journal of Medical and Biological Research. Publicado em: 2010-08
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4. NUMERICAL MODELING OF VIRUS TRANSPORT IN FRACTURED-POROUS MEDIA / MODELAGEM NUMÉRICA DO TRANSPORTE DE VÍRUS EM AQÜÍFEROS FRATURADOS - POROSOS
Setback distances of wellhead and catchments from septic tanks are establised by three aproaches: methods based on fixed setback distances or fixed travel times; methods based on vulnerability analysis and methods based on infection risk. In Costa Rica, the determination of setback distances is based on fixed travel times. This approach considers that during
Publicado em: 2008
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5. Movimento bidirecional no transporte intracelular mediado por motores moleculares / Bidirectional movement in the intracellular transport mediated by molecular motors
In this work we present a theoretical model to describe aspects of the bidirectional movement performed by intracellular structures (vesicles, organelles, viruses etc, to which we refer here simply as "vesicles"), observed essentially at in vivo experiments. This nondifusive movement is characterized by rapid inversions in direction and is capable of creatin
Publicado em: 2007
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6. Isolation of respiratory syncytial virus from nasopharyngeal aspirates stored at 20ºC from one to fifteen months after collection
Cell culture isolation is used for recovering respiratory syncytial virus (RSV) from respiratory specimens. As RSV is a thermolabile virus, specimens destined for inoculation into cell culture require special transport, handling, and storage. The isolation rate of RSV from nasopharyngeal aspirates (NPA) stored at 20ºC for one to 15 months after collection w
Memórias do Instituto Oswaldo Cruz. Publicado em: 2006-06
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7. Caracterização do vírus dengue circulante no Estado de Rondônia
The dengue virus is more important disease transmited by mosquitoes in terms of morbidity and mortality. The Aedes aegypti is the unique vector of the epidemiologic importance for dengue virus transmission in the America. The symptoms of dengue are characterized by acute febrile, accomplished of headache, retro-orbital pain and muscle and bone or joint pains
Publicado em: 2005
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8. Gene expression in IFN-gamma-activated murine macrophages
Macrophages are critical for natural immunity and play a central role in specific acquired immunity. The IFN-gamma activation of macrophages derived from A/J or BALB/c mice yielded two different patterns of antiviral state in murine hepatitis virus 3 infection, which were related to a down-regulation of the main virus receptor. Using cDNA hybridization to ev
Brazilian Journal of Medical and Biological Research. Publicado em: 2004-12
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9. The GDVII Strain of Theiler’s Virus Spreads via Axonal Transport
Following intracerebral inoculation, the DA strain of Theiler’s virus sequentially infects neurons in the gray matter and glial cells in the white matter of the spinal cord. It persists in the latter throughout the life of the animal. Several observations suggest that the virus spreads from the gray to the white matter by axonal transport. In contrast, the
American Society for Microbiology.
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10. Transport of viral specimens.
The diagnosis of viral infections by culture relies on the collection of proper specimens, proper care to protect the virus in the specimens from environmental damage, and use of an adequate transport system to maintain virus activity. Collection of specimens with swabs that are toxic to either virus or cell culture should be avoided. A variety of transport
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11. Different Patterns of Neuronal Infection after Intracerebral Injection of Two Strains of Pseudorabies Virus
Pseudorabies virus (PRV), a swine neurotropic alphaherpesvirus, is known to invade the central nervous system (CNS) of a variety of animal species through peripherally projecting axons, replicate in the parent neurons, and then pass transsynaptically to infect other neurons of a circuit. Studies of the human pathogen herpes simplex virus type 1 have reported
American Society for Microbiology.
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12. Phosphatidylinositol 3-kinase binding to polyoma virus middle tumor antigen mediates elevation of glucose transport by increasing translocation of the GLUT1 transporter.
Elevation in the rate of glucose transport in polyoma virus-infected mouse fibroblasts was dependent upon phosphatidylinositol 3-kinase (PI 3-kinase; EC 2.7.1.137) binding to complexes of middle tumor antigen (middle T) and pp60c-src. Wild-type polyoma virus infection led to a 3-fold increase in the rate of 2-deoxyglucose (2DG) uptake, whereas a weakly trans