Vegf System
Mostrando 13-24 de 60 artigos, teses e dissertações.
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13. Identificação da expressão do vascular endothelial growth factor (VEGF) pela contagem de células marcadas imunoistoquimicamente no omento de ratos após ligadura arterial e após ligadura venosa
O sistema cardiovascular está estrutural e funcionalmente disposto de modo “circular”. Situações de obstrução do fluxo sanguíneo determinam o aparecimento de mecanismos que visam suplantar tais interrupções e manter a circularidade íntegra. À nível molecular, o principal elemento envolvido nestes mecanismos é o Vascular Endothelial Growth Fac
Publicado em: 2008
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14. Expressão de fatores angiogênicos em corpo lúteo cíclico e superovulado de búfalas / Expression of angiogenic factors in cyclic and superovulated bufallo corpus luteum
Biotechniques can be an effective way of improving reproduction efficiency and enhancing the production of genetically superior animals. The superovulatory treatment is a common technique aiming to spread desired genetical material, although its use in buffalos still presents limitations, mainly the low embryo recovery rate. The corpus luteum (CL) is a tempo
Publicado em: 2008
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15. Análise comparativa das distribuições espaciais de moléculas envolvidas na migração e invasão de um tumor cerebral de rato in vivo. / Comparative analysis of spatial distribution of molecules related to migration an invasion in a rat brain tumor in vivo.
O Glioblastoma multiforme (GBM) é o mais maligno tumor cerebral e apresenta uma alta capacidade proliferativa, invasiva e angiogênica. Neste estudo foi avaliada a distribuição espacial de moléculas envolvidas nesses processos num modelo de GBM de rato in vivo (C6). Por imunohistoquímicas observou-se que o tumor foi capaz de expressar diferentes element
Publicado em: 2008
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16. Células-tronco mesenquimais :caracterização e potencial de diferenciaçãoa cardiomiócitos induzida por doadores de óxido nítrico (SNAP e DEA/NO)
Introdução: A terapia celular para o tratamento de doenças cardíacas é um método terapêutico novo que pode levar a recuperação da função do miocárdio. Porém a fonte de células e o tipo celular com propriedades adequadas de regeneração do tecido cardíaco estão sendo pesquisadas. As células-tronco mesenquimais (CTMs) possuem propriedades que
Publicado em: 2008
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17. Serum amyloid A: biological effects on mononuclear cells / Amilóide sérica A: efeitos biológicos sobre células mononucleares
In the past few years, our research group has described various effects of serum amyloid A (SAA) on cells of the immune system regarding the expression and release of pro-inflammatory cytokines. In this study we have focused on the effects of SAA on mononuclear cells. In order to do this, we have used three experimental models. In the murine experimental mod
Publicado em: 2008
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18. Estabelecimento de um modelo experimental de neurotuberculose / Establishment of an experimental model of neurotuberculosis
A tuberculose (TB) é um grave problema de saúde pública. Somente no ano de 2004, cerca de 9 milhões de pessoas desenvolveram TB ativa e mais de 2 milhões de pessoas morreram da doença. O desenvolvimento de novos modelos experimentais de TB seriam de grande utilidade para para elucidar mecanismos fisiopatológicos da doença e testar esquemas terapêuti
Publicado em: 2007
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19. Comparative study of the VEGF system temporal distribution in the bovine and canine placenta / Estudo comparativo da distribuição temporal do sistema VEGF na placenta de cães e de bovinos
The VEGF family is known to be responsible for the angiogenesis increasing blood vessels number and permeability in the endometrial/placentary interface. A comparative study of VEGF system temporal distribution in canine and bovine placentas, which present very well described differences in structure and function, will contribute to better define the role of
Publicado em: 2006
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20. Expression of mRNA of the VEGF, Flt-1 and KDR in placentome, interplacentomal areas and gestational corpus luteum in different phases of pregnancy in cloned and non-cloned bovines / Expressão do mRNA do VEGF, FIt-1 e KDR no placentoma, região interplacentomal e corpo lúteo em diferentes fases gestacionais em bovinos clonados e não clonados
The VEGF is a specific endothelial mitogenic factor that promotes feto-maternal cell differentiation in placenta through binding to its receptors (Flt-1 and KDR). Their expression is controlled by autocrine and paracrine mechanisms that are associated to placenta development. The bovine placenta was used in this study as a model due to easiness of evaluation
Publicado em: 2006
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21. Immunolocalization of VEGF, bFGF and their receptors in the bovine placenta and influence of these growth factors on progesterone production from placental cells in culture / Imunolocalização do VEGF, bFGF e seus receptores na placenta bovina e influência destes fatores sobre a produção de progesterona pelas células placentárias em cultura
Placental establishment and function are dependent on intense vascularization. Placental vasculogenesis and angiogenesis are modulated by several factors, including VEGF (vascular endothelial growth factor) and bFGF (basic fibroblast growth factor). Although the role of VEGF and bFGF during vascularization is already well established, some studies have indic
Publicado em: 2005
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22. VEGF immunoexpression in penile carcinoma
OBJECTIVE: To investigate the vessel endothelial growth factor (VEGF) as a risk factor in squamous cell carcinoma of the penis (SCCP). METHODS: Forty-seven patients with penile carcinoma were evaluated retrospectively. The mean age and standard deviation were 61.1±11.7 years. All of them were treated by penectomy and those with positive nodes underwent groi
Acta Cirurgica Brasileira. Publicado em: 2002
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23. Conditional switching of VEGF provides new insights into adult neovascularization and pro-angiogenic therapy
To gain insight into neovascularization of adult organs and to uncover inherent obstacles in vascular endothelial growth factor (VEGF)-based therapeutic angiogenesis, a transgenic system for conditional switching of VEGF expression was devised. The system allows for a reversible induction of VEGF specifically in the heart muscle or liver at any selected sche
Oxford University Press.
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24. Conditional switching of vascular endothelial growth factor (VEGF) expression in tumors: Induction of endothelial cell shedding and regression of hemangioblastoma-like vessels by VEGF withdrawal
We have recently shown that VEGF functions as a survival factor for newly formed vessels during developmental neovascularization, but is not required for maintenance of mature vessels. Reasoning that expanding tumors contain a significant fraction of newly formed and remodeling vessels, we examined whether abrupt withdrawal of VEGF will result in regression
The National Academy of Sciences of the USA.