Vacuolating Autotransporter Toxin
Mostrando 1-5 de 5 artigos, teses e dissertações.
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1. Vat (vacuolating autotransporter toxin) produced by APEC (avian pathogenic Escherichia coli) : intracellular effects and philogroups distribution / Vat (vacuolating autotransporter toxin) produzida por APEC (avian pathogenic Escherichia coli) : efeitos intracelulares e distribuição filogenetica
Escherichia coli isoladas de lesões de celulite aviária em frangos de corte produzem uma citotoxina que causa intensa vacuolização citoplasmática em células de origem aviária, mas não em células de mamíferos. Esta citotoxina foi denominada Vat (vacuolating autotransporter toxin) e apresenta massa molecular de 56 kDa e ponto isoelétrico de 6,37. Es
Publicado em: 2010
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2. Outer Membrane Targeting of Passenger Proteins by the Vacuolating Cytotoxin Autotransporter of Helicobacter pylori
Helicobacter pylori produces a number of proteins associated with the outer membrane, including adhesins and the vacuolating cytotoxin. These proteins are supposed to integrate into the outer membrane by β-barrel structures, characteristic of the family of autotransporter proteins. By using the SOMPES (shuttle vector-based outer membrane protein expression)
American Society for Microbiology.
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3. A Novel Pathogenicity Island Integrated Adjacent to the thrW tRNA Gene of Avian Pathogenic Escherichia coli Encodes a Vacuolating Autotransporter Toxin
We report the complete nucleotide sequence and genetic organization of the Vat-encoding pathogenicity island (PAI) of avian pathogenic Escherichia coli strain Ec222. The 22,139-bp PAI is situated adjacent to the 3′ terminus of the thrW tRNA gene, has a G+C content of 41.2%, and includes a bacteriophage SfII integrase gene, mobile genetic elements, two open
American Society for Microbiology.
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4. Carboxy-Terminal Proteolytic Processing of Helicobacter pylori Vacuolating Toxin
The vacA gene of Helicobacter pylori strain 60190 encodes a 1,287-amino-acid protoxin, which undergoes cleavage of a 33-amino-acid amino-terminal signal sequence and carboxy-terminal proteolytic processing to yield a mature secreted toxin. Several features of VacA suggest that it belongs to the autotransporter family of gram-negative bacterial secreted prote
American Society for Microbiology.
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5. Sat, the Secreted Autotransporter Toxin of Uropathogenic Escherichia coli, Is a Vacuolating Cytotoxin for Bladder and Kidney Epithelial Cells
The secreted autotransporter toxin (Sat) of uropathogenic Escherichia coli exhibits cytopathic activity upon incubation with HEp-2 cells. We further investigated the effects of Sat on cell lines more relevant to the urinary tract, namely, those derived from bladder and kidney epithelium. Sat elicited elongation of cells and apparent loosening of cellular jun
American Society for Microbiology.