Ursolic Acid
Mostrando 1-12 de 47 artigos, teses e dissertações.
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1. Iridoides, triterpenos e outros constituintes das cascas do caule e flores de Tabebuia caraiba Bignoniaceae
The trunk bark of Tabebuia caraiba Bignoniaceae was found to contain four novel iridoids, 6-O-E-p-coumaroyljioglutin D (2), 6-O-E-p-coumaroyl-3-demethyl-3-O-ethyljioglutin D (3), 6-O-E-p-coumaroyl-1-demethyl-1-O-ethyljioglutin D (4), 7-O-E-p-coumaroyljiofuranaldehyde (5), three known iridoids, including one iridoid glucoside, jioglutin D (1), rehmaglutin D (
Quím. Nova. Publicado em: 2020-04
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2. Minutifloroside, a New Bis-Iridoid Glucoside with Antifungal and Antioxidant Activities and Other Constituents from Palicourea minutiflora
A new bis-iridoid glucoside minutifloroside (1) was isolated from Palicourea minutiflora, together with asperuloside, (-)-epicatechin, catechin, quercetin, rutin, ursolic acid, oleanolic acid, daucosterol and two monoterpenic indole alkaloids strictosidinic acid and vincosamine. Structural characterization of the compounds was established on their spectral d
J. Braz. Chem. Soc.. Publicado em: 2020-03
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3. CHEMICAL CONSTITUENTS OF Sinningia mauroana AND SCREENING OF ITS EXTRACTS FOR ANTIMICROBIAL, ANTIOXIDANT AND CYTOTOXIC ACTIVITIES
Phytochemical study of aerial parts from Sinningia mauroana Chautems (Gesneriaceae) yielded 17 known compounds: sitosterol, stigmasterol, betulinic acid, oleanolic acid, hederagenin, maslinic acid, ursolic acid, pomolic acid, soranjidiol, methyl 4-hydroxyphenylacetate, 6-hydroxy-7-methoxy-α-dunnione, 7-hydroxy-6-methoxy-α-dunnione, jacaranone, calceolarios
Quím. Nova. Publicado em: 2020-02
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4. Evaluation of triterpenes derivatives in the viability of Leishmania amazonensis and Trichomonas vaginalis
Trichomonas vaginalis and Leishmania spp. are protozoal species responsible for millions of cases of parasitic diseases worldwide. Considering the potential of natural products and the need for more effective and less toxic alternatives to treat trichomoniasis and leishmaniasis, this study aimed to evaluate the effect of two series of triterpenes derivatives
Braz. J. Pharm. Sci.. Publicado em: 20/12/2019
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5. Chemical diversity and activity profiles of HIV-1 reverse transcriptase inhibitors from plants
Abstract Current challenges to antiretroviral therapy have opened new vistas in the search for novel drugs from natural products. This review focusses on plants as sources of inhibitors for human immunodeficiency virus type 1 (HIV-1) reverse transcriptase. Based on a systematic search of the literature, anti-HIV-1 reverse transcriptase activity was recorded
Rev. bras. farmacogn.. Publicado em: 17/10/2019
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6. URSOLIC ACID AND CIS-TILIROSIDE PRODUCED BY Merremia tomentosa AFFECT OVIPOSITION OF Leucoptera coffeella ON COFFEE PLANTS
To contribute to the development of new products to control the coffee leaf miner (Leucoptera coffeella), which is a major pest for coffee plants, this work aimed to select plant species able to produce substances active against this insect and to identify the active substances in the selected plant and their protein targets in the insect. Among the extracts
Quím. Nova. Publicado em: 2018-03
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7. Anti-inflammatory and antioxidant activities of the Impatiens noli-tangere and Stachys officinalis polyphenolic-rich extracts
ABSTRACT This study evaluated the anti-inflammatory and antioxidant activities of Impatiens noli-tangere L., Balsaminaceae, and of Stachys officinalis L., Lamiaceae, polyphenolic-rich extracts obtained by nanofiltration process. Results showed the great potential and efficiency of the nanofiltration process to concentrate the herbal extract's main polyphenol
Rev. bras. farmacogn.. Publicado em: 2018-01
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8. CONSTITUINTES QUÍMICOS E ATIVIDADE INSETICIDA DE Miconia ferruginata
Phytochemical investigation of the leaf extracts from Miconia ferruginata (Melastomataceae) led to the isolation and characterization of the flavonoids 5,6,7-trihydroxy-4'-methoxyflavone, 5-hydroxy-7,4'-dimethoxy-8-methylflavone and 5,7,4'-trihydroxy-6,8-dimetilflavone, triterpenes ursolic acid and oleanolic acid, in addition to the steroids β-sitosterol an
Quím. Nova. Publicado em: 2017-10
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9. Terpene Esters from Natural Products: Synthesis and Evaluation of Cytotoxic Activity
ABSTRACT Natural steroids and triterpenes such as b-sitosterol, stigmasterol, lupeol, ursolic and betulinic acids were transformed into its hexanoic and oleic esters, to evaluate the influence of chemical modification towards the cytotoxic activities against tumor cells. The derivatives were evaluated against five tumor cell lines [OVCAR-8 (ovarian carcinoma
An. Acad. Bras. Ciênc.. Publicado em: 14/08/2017
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10. Psychotria viridis: Chemical constituents from leaves and biological properties
ABSTRACT The phytochemical study of hexane, chloroform and methanol extracts from leaves of Psychotria viridis resulted in the identification of: the pentacyclic triterpenes, ursolic and oleanolic acid; the steroids, 24-methylene-cycloartanol, stigmasterol and β-sitosterol; the glycosylated steroids 3-O-β-D-glucosyl-β-sitosterol and 3-O-β-D-glucosyl-stig
An. Acad. Bras. Ciênc.. Publicado em: 2017-06
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11. Evaluation of cytogenotoxicity, antioxidant and hypoglycemiant activities of isolate compounds from Mansoa hirsuta D.C. (Bignoniaceae)
ABSTRACT Mansoa hirsuta (Bignoniaceae) is a native plant from caatinga in Brazilian semiarid. This plant has been locally used as antimicrobial and hypoglycemiant agents, but their action mechanisms and toxicity remain largely unknown. Therefore, we evaluated the composition and antioxidant, cytoprotective and hypoglycemiant effects of raw extract, fractions
An. Acad. Bras. Ciênc.. Publicado em: 2017-03
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12. CHEMICAL CONSTITUENTS, ANTI-INFLAMMATORY, AND FREE-RADICAL SCAVENGING ACTIVITIES OF Guettarda viburnoides CHAM. & SCHLTDL. (RUBIACEAE)
Chemical investigation of Guettarda viburnoides (leaves) led to the isolation of ursolic acid, uncaric acid, secoxyloganin, and grandifloroside, along with a mixture of quercetin-3-O-β-D-galactopyranoside and quercetin-3-O-β-D-glucopyranoside, and of β-sitosterol and stigmasterol. The structures of the isolated compounds were elucidated on the basis of th
Quím. Nova. Publicado em: 2015-08