Trypanosomatids
Mostrando 13-24 de 146 artigos, teses e dissertações.
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13. Symbiont modulates expression of specific gene categories in Angomonas deanei
Trypanosomatids are parasites that cause disease in humans, animals, and plants. Most are non-pathogenic and some harbor a symbiotic bacterium. Endosymbiosis is part of the evolutionary process of vital cell functions such as respiration and photosynthesis. Angomonas deanei is an example of a symbiont-containing trypanosomatid. In this paper, we sought to in
Mem. Inst. Oswaldo Cruz. Publicado em: 03/10/2016
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14. Functional complementation of Leishmania (Leishmania) amazonensis AP endonuclease gene (lamap) in Escherichia coli mutant strains challenged with DNA damage agents
During its life cycle Leishmania spp. face several stress conditions that can cause DNA damages. Base Excision Repair plays an important role in DNA maintenance and it is one of the most conserved mechanisms in all living organisms. DNA repair in trypanosomatids has been reported only for Old World Leishmania species. Here the AP endonuclease from Leishmania
Mem. Inst. Oswaldo Cruz. Publicado em: 2016-05
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15. Molecular detection of Trypanosoma sp. and Blastocrithidia sp. (Trypanosomatidae) in phlebotomine sand flies (Psychodidae) in the Federal District of Brazil
Abstract: INTRODUCTION : This study describes the occurrence of trypanosomatids in phlebotomines in Brasília, Brazil. METHODS : Two hundred and ten females of 13 sand fly species were analyzed by polymerase chain reaction (PCR) using different molecular markers (D7 24Sα rRNA, kDNA, and ITS1) and sequencing. RESULTS : PCR revealed trypanosomatid-positive
Rev. Soc. Bras. Med. Trop.. Publicado em: 2015-12
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16. Report of new cases of Trypanosoma caninum in Brazil
INTRODUCTION: Trypanosoma caninum is a protozoan species recently described in dogs, whose occurrence has been reported in areas of overlap with visceral leishmaniasis. METHODS: Trypanosoma sp. were isolated from nine dogs and characterized by molecular methods. RESULTS: PCR and sequencing confirmed the presence of T. caninum in all dogs, revealing two new
Rev. Soc. Bras. Med. Trop.. Publicado em: 2015-06
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17. Mechanisms of growth inhibition of Phytomonas serpens by the alkaloids tomatine and tomatidine
Phytomonas serpens are flagellates in the family Trypanosomatidae that parasitise the tomato plant (Solanum lycopersicum L.), which results in fruits with low commercial value. The tomato glycoalkaloid tomatine and its aglycone tomatidine inhibit the growth of P. serpens in axenic cultures. Tomatine, like many other saponins, induces permeabilisation of the
Mem. Inst. Oswaldo Cruz. Publicado em: 13/02/2015
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18. In silico molecular modeling and docking studies on the leishmanial tryparedoxin peroxidase
Leishmaniasis is one of the most common form of neglected parasitic disease that affects about 350 million people worldwide. Leishmanias have a trypanothione mediated hydroperoxide metabolism to eliminate endogenous or exogenous oxidative agents. Both of 2-Cys peroxiredoxin (Prx) and glutathione peroxidase type tryparedoxin peroxidase (Px) are the terminal e
Braz. arch. biol. technol.. Publicado em: 2014-04
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19. Slow wilt: another form of Marchitez in oil palm associated with trypanosomatids in Peru
Another form of Marchitez manifestation affecting oil palm (Elaeis guineensis) has been observed since 2002 in the Alto Huallaga area from Peru. Externally, the disease appears as chlorosis, drying and breaking of the lower leaves, rot in fruit bunches, accumulation and rot of spears. Internally, the meristem presents brown lesions with a yellowish halo arou
Trop. plant pathol.. Publicado em: 2013-12
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20. Combination of the essential oil constituents citral, eugenol and thymol enhance their inhibitory effect on Crithidia fasciculata and Trypanosoma cruzi growth
We analyzed the effect of the combination of citral, eugenol and thymol, respectively the main constituents of essential oils of Cympobogon citratus (DC) Stapf, Poaceae (lemon grass), Syzygium aromaticum(L.) Merr. & L.M. Perry, Myrtaceae (clove) and Thymus vulgarisL., Lamiaceae (thyme), on the proliferation of the trypanosomatids Crithidia fasciculataand Try
Rev. bras. farmacogn.. Publicado em: 2013-10
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21. Actin expression in trypanosomatids (Euglenozoa: Kinetoplastea)
Heteroxenic and monoxenic trypanosomatids were screened for the presence of actin using a mouse polyclonal antibody produced against the entire sequence of the Trypanosoma cruzi actin gene, encoding a 41.9 kDa protein. Western blot analysis showed that this antibody reacted with a polypeptide of approximately 42 kDa in the whole-cell lysates of parasites tar
Mem. Inst. Oswaldo Cruz. Publicado em: 2013-08
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22. Efeito da 1,10-fenantrolina e seus derivados complexados em metal na atividade proteolítica de Leishmania braziliensis / Effect of 1,10-phenanthroline and its derivatives complexed metal in the proteolytic activity of Leishmania braziliensis
Leishmanioses são um grupo de doenças com um largo espectro de manifestações clínicas, as quais variam desde lesões cutâneas até o envolvimento visceral severo, podendo levar ao óbito. A leishmaniose é, ainda hoje, uma doença negligenciada, estando entre os agravos prioritários do programa de pesquisa sobre doenças da pobreza da Organização Mu
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 24/08/2012
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23. Planejamento de inibidores das enzimas diidroorotato desidrogenase de Trypanosoma cruzi e Leishmania major / Design of inhibitors for dihydroorotate dehydrogenase from Trypanosoma cruzi and Leishmania major
Dihydroorotate dehydrogenase (DHODH) catalyses the conversion of dihydroorote to orotate, the fourth step and only redox reaction in the de novo pyrimidine biosynthetic pathway. DHODH has been exploited as a validated target for therapy against proliferative and parasitic diseases, and in particular, has been considered to be an attractive target for drug de
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 25/04/2012
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24. Identification of SL addition trans-splicing acceptor sites in the internal transcribed spacer I region of pre-rRNA in Leishmania (Leishmania) amazonensis
Trypanosomatidae is a family of early branching eukaryotes harbouring a distinctive repertoire of gene expression strategies. Functional mature messenger RNA is generated via the trans-splicing and polyadenylation processing of constitutively transcribed polycistronic units. Recently, trans-splicing of pre-small subunit ribosomal RNA in the 5' external trans
Mem. Inst. Oswaldo Cruz. Publicado em: 2012-12