Triple Negative
Mostrando 1-12 de 141 artigos, teses e dissertações.
-
1. An easy and practical prognostic parameter: tumor–stroma ratio in Luminal, Her2, and triple-negative breast cancers
SUMMARY OBJECTIVE: The stroma surrounding the tumor cells is important in tumor progression and treatment resistance, besides the properties of tumor cells. Studies on the tumor stroma characteristics will contribute to the knowledge for new treatment approaches. METHODS: A total of 363 breast cancer patients were evaluated for the tumor–stroma ratio. Th
Revista da Associação Médica Brasileira. Publicado em: 2022
-
2. Immunohistochemical and clinicopathologic features of estrogen receptor-negative, progesterone receptor-positive, HER-2 negative breast carcinomas
SUMMARY OBJECTIVE: Currently, there is an ongoing debate whether progesterone receptor positive and estrogen receptor negative breast carcinomas represent a true distinct subtype of tumor or a mere immunohistochemical artifact. In this study, we conducted an immunohistochemistry panel with the antibodies TFF1, EGFR, and CK5 to reclassify this phenotype in a
Rev. Assoc. Med. Bras.. Publicado em: 2021-02
-
3. Metamaterial-Fractal-Defected Ground Structure Concepts Combining for Highly Miniaturized Triple-Band Antenna Design
Abstract In this paper, a novel method is proposed to increase the gain and radiation efficiency of a compact patch antenna. By employing a combination of three efficient techniques, we have developed a multi-resonance L-DGS antenna with a high gain of 5 dB and an efficiency of 99.6%. Furthermore, a novel compact Double Negative metamaterial unit cell and it
J. Microw. Optoelectron. Electromagn. Appl.. Publicado em: 2020-12
-
4. Clinical and molecular profile of a Brazilian cohort of patients with classical BCR-ABL1-negative myeloproliferative neoplasms
ABSTRACT Background: The classical BCR-ABL1-negative myeloproliferative neoplasms (MPNs) are Polycythemia Vera (PV), Essential Thrombocythemia (ET) and Primary Myelofibrosis (PMF). In developing countries, there are few reports that truly reveal the clinical setting of these patients. Therefore, we aimed to characterize a single center MPN population with a
Hematol., Transfus. Cell Ther.. Publicado em: 2020-09
-
5. Structural Study of Phenolic Acids by Triple Quadrupole Mass Spectrometry with Electrospray Ionization in Negative Mode and H/D Isotopic Exchange
This work reports the theoretical and experimental study of fragmentation reactions in the gas phase of five phenolic acids using triple quadrupole mass spectrometry by electrospray ionization in negative ionic mode, as well as the isotope exchange experiments. MS/MS spectra were analyzed to suggest the fragmentation mechanisms, while theoretical calculation
J. Braz. Chem. Soc.. Publicado em: 2020-02
-
6. Follow-up of Toxoplasmosis during Pregnancy: Ten-Year Experience in a University Hospital in Southern Brazil
Resumo Objetivo Descrever uma população de pacientes diagnosticadas com toxoplasmose na gestação e seus respectivos recém-nascidos, relatando o protocolo do hospital durante o tratamento e seguimento. Métodos Coorte retrospectiva de gestantes com infecção aguda por toxoplasmose e risco de transmissão transplacentária, encaminhadas para acompanh
Rev. Bras. Ginecol. Obstet.. Publicado em: 30/09/2019
-
7. [PROVISIONAL] Large miRNA survival analysis reveals a prognostic four-biomarker signature for triple negative breast cancer
Abstract Triple negative breast cancer (TNBC) is currently the only major breast tumor subtype without effective targeted therapy and, as a consequence, usually presents a poor outcome. Due to its more aggressive phenotype, there is an urgent clinical need to identify novel biomarkers that discriminate individuals with poor prognosis. Our hypothesis is that
Genet. Mol. Biol.. Publicado em: 05/09/2019
-
8. Accuracy of breast magnetic resonance imaging in evaluating the response to neoadjuvant chemotherapy: a study of 310 cases at a cancer center
Resumo Objetivo: Avaliar a acurácia da ressonância magnética (RM) das mamas na identificação de resposta patológica completa em pacientes com câncer de mama submetidas a quimioterapia neoadjuvante (QTN). Materiais e Métodos: Teste de validação diagnóstica, realizado por meio de estudo observacional, unicêntrico e retrospectivo. As variáveis av
Radiol Bras. Publicado em: 08/08/2019
-
9. Corrective phosphate application as a practice for reducing oxidative stress and increasing productivity in sugarcane
RESUMO A fosfatagem aumenta os teores de fósforo (P) na camada superficial do solo, estimula o crescimento das raízes das plantas e aumenta o volume de solo explorado para absorção de água e nutrientes, o que pode reduzir o estresse oxidativo abiótico na cana-de-açúcar. O objetivo deste trabalho foi avaliar a produtividade e a resposta do sistema enz
Rev. Ciênc. Agron.. Publicado em: 2019-06
-
10. Association of FOSL1 copy number alteration and triple negative breast tumors
Abstract Copy number alterations (CNAs) are a frequent feature in human breast cancer, and one of the hallmarks of genomic instability. The FOSL1, GSTP1 and CCND1 genes are located at 11q13, a cytoband commonly affected by CNA in breast cancer, with relevant function in progression and invasion. Our main goal was to analyze CNAs of these genes and determine
Genet. Mol. Biol.. Publicado em: 28/02/2019
-
11. Simultaneous Determination of Kaempferide, Kaempferol and Isorhamnetin in Rat Plasma by Ultra-High Performance Liquid Chromatography-Tandem Mass Spectrometry and its Application to a Pharmacokinetic Study
A selective, rapid and sensitive method using ultra-high performance liquid chromatography was developed and used for the simultaneous determination of kaempferide, kaempferol, and isorhamnetin in rat plasma after oral administration of Sedumsarmentosum Bunge extract. A 6430 triple-quadrupole tandem mass spectrometer in multiple reaction monitoring mode, wit
J. Braz. Chem. Soc.. Publicado em: 2018-03
-
12. Regenerative Endodontic Treatment as a Retreatment Option for a Tooth with Open Apex - A Case Report
Abstract: Treatment of non-vital immature teeth with apical periodontitis has always been a challenge in Endodontics. Regenerative endodontic treatment (RET) has been successfully used for the management of these cases. The aim of this study is to present a case of RET used for the retreatment of a previously endodontically treated permanent tooth with an op
Braz. Dent. J.. Publicado em: 2015-10