Toxicological Evaluation
Mostrando 13-24 de 70 artigos, teses e dissertações.
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13. Biologically active compounds from cyanobacteria extracts: in vivo and in vitro aspects
An investigation was directed towards the antiacetylcholinesterase activity of the acid aqueous and methanolic extracts of five cyanobacterial taxa, which encompasses an enzymatic inhibition essay and the evaluation of the physiological responses of mice to cyanobacterial extracts along with toxicological observations. The strains Calothrix sp. CCIBt 3320, T
Rev. bras. farmacogn.. Publicado em: 14/05/2013
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14. Maternal exposure to Cochlospermum regium: a toxicological evaluation
Cochlospermum regium (Schrank) Pilg., Bixaceae, is a Brazilian plant widely used as a folk medicine in the southwestern of the Brazil to treat inflammation and infection diseases. However, the effects of C. regium hydroethanolic extract on pregnant rats have not been assessed. To evaluate the effects of the C. regium on pregnant rats during the organogenic p
Rev. bras. farmacogn.. Publicado em: 01/02/2013
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15. Estudo da atividade citotóxica do poliacetileno 5-octa-2, 4, 6-triinil-furan-2(5H)-ona / Study of the cytotoxic activity of polyacetylene 5-octa-2,4,6-triinil-furan-2 (5H)-one
Skin cancers are the most common types of cancer in Brazil, and correspond to around 25% of all malignant tumors recorded. Of these, melanoma represents at least 5% and is characterized by its high metastatic power. The development of anticancer agents from natural products is considered critical to pharmacology, and interest in the development of more effec
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 26/06/2012
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16. Toxicological evaluation of vegetable oils and biodiesel in soil during the biodegradation process
Vegetable oils and their derivatives, like biodiesel, are used extensively throughout the world, thus posing an environmental risk when disposed. Toxicity testing using test organisms shows how these residues affect ecosystems. Toxicity tests using earthworms (Eisenia foetida. are widespread because they are a practical resource for analyzing terrestrial org
Braz. J. Microbiol.. Publicado em: 2012-12
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17. Biodegradation and toxicological evaluation of lubricant oils
The aim of this work was to compare different toxicity levels of lubricant oils. The tests were performed using the earthworm (Eisenia andrei), arugula seeds (Eruca sativa) and lettuce seeds (Lactuca sativa), with three types of contaminants (mineral lubricant oil, synthetic lubricant oil and used lubricant oil) for various biodegradation periods in the soil
Braz. arch. biol. technol.. Publicado em: 2012-12
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18. Toxicological evaluation of ethanolic extract of Lychnophora trichocarpha, Brazilian arnica
The species of the genus Lychnophora, Asteraceae, are popularly known as "arnica" and are native from Brazilian savana (Cerrado). They are widely used in Brazilian folk medicine as anti-inflammatory, to treat bruise, pain, rheumatism and for insect bites. For evaluation of acute toxicity, the ethanolic extract was given to albino female and male mice. In ope
Rev. bras. farmacogn.. Publicado em: 17/07/2012
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19. Toxicological and pharmacological evaluation of Discaria americana Gillies & Hook (Rhamnaceae) in mice
As plantas medicinais (i. e. Discaria americana) têm sido utilizadas pela população por séculos, entretanto, o conhecimento popular não é suficiente para validá-las como medicamentos seguros e/ou efetivos. Assim, o presente estudo teve por objetivo avaliar a toxicidade aguda e subaguda, bem como o efeito ansiolítico e antinociceptivo dos extratos da
Brazilian Journal of Pharmaceutical Sciences. Publicado em: 2012-06
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20. Acute and subchronic toxicological evaluation of Echinophora platyloba DC (Apiaceae) total extract in Wistar rats
OBJECTIVE: Echinophora platyloba DC is a widely used herbal medicine and food seasoning in Iran. It is claimed to exert antimicrobial, antifungal, and antispasmodic effects. Despite the prevalent use of this plant as a food and medicine, there are no reports on its possible toxic effects. To evaluate the safety of E. platyloba, we tested its acute and sub-ch
Clinics. Publicado em: 2012
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21. Análise química e toxicológica de suplementos alimentares e compostos emagrecedores contendo p-sinefrina associada a efedrina, salicina e cafeína
Os suplementos alimentares e compostos emagrecedores a base de extratos vegetais têm uso muito difundido e indiscriminado, principalmente pela diversidade de produtos disponíveis e facilidade de acesso aos mesmos, aliada à falsa crença popular de que ¿o que é natural não faz mal¿. Produtos contendo a associação de psinefrina, efedrina, salicina e c
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 2012
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22. AVALIAÇÃO TOXICOLÓGICA DE COMPOSTOS ORGÂNICOS DE TELÚRIO SOBRE O DESENVOLVIMENTO PRÉ-NATAL EM CAMUNDONGOS / TOXICOLOGICAL EVALUATION OF ORGANOTELLURIUM COMPOUNDS ON PRENATAL DEVELOPMENT IN MIC
É sabido que a maioria dos agentes químicos atravessam facilmente a placenta e, dessa maneira, pode-se considerar que a exposição materna a agentes externos pode resultar em efeitos tóxicos sobre o organismo embrio-fetal. Considerando as características químicas dos compostos orgânicos de telúrio, tais como a solubilidade lipídica e o peso molecula
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 25/03/2011
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23. Toxicological evaluation of the João da Costa e Associações® on Beagle dogs
A toxicological study was performed in Beagle dogs treated for 180 days with the product João da Costa e Associações. Were used six males and six females distributed in control and treated groups (n=3). We used a dose of 566 mg/kg of the product according to preclinical study in rodents. The animals were weighed and evaluated by clinical and laboratory as
Revista Brasileira de Farmacognosia. Publicado em: 21/11/2011
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24. DETERMINATION OF POLYCHLORINATED BIPHENYLS IN POWDERED MILK AND ESTIMATED DAILY INGESTION IN PRE-SCHOLARS / DETERMINAÇÃO DE BIFENILOS POLICLORADOS EM LEITE EM PÓ E INGESTÃO DIÁRIA ESTIMADA POR PRÉ-ESCOLARES
The polychlorinated biphenyls are synthetic organoclorated substances that can produce noxious effects to health. There are not any natural sources of PCBs known in the environment. They can be liquid or solid, colorless or clear yellow. Some of them are volatile and may remain as steams in the air. They were widely used in the industry as oils for transform
Publicado em: 2010