Tissue Inhibitor Of Metalloproteinases
Mostrando 1-12 de 95 artigos, teses e dissertações.
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1. Salivary glands of fetuses are adversely affected by artificial food colorings in rats
SUMMARY OBJECTIVE: Artificial food colorings, as types of food additives, are widely used at present in daily life. We aimed to investigate the effects of exposure to artificial food colorings during the intrauterine period on the salivary glands in adulthood. METHODS: A total of 30 Wistar albino female pregnant rats were included in this study. The treatm
Rev. Assoc. Med. Bras.. Publicado em: 2021-02
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2. Is the Expression of the Components of the Carotid Matrix of Rats Influenced by Estrogen, Progestin and Tibolone?
Resumo Objetivo Analisar os efeitos do estrogênio isolado ou em combinação com progestogênios e tibolona (TIB) na expressão das metaloproteinases 2 e 9 da matriz extracelular (MMP-2 e MMP-9), da perlecan e da heparanase (HPSE) das paredes vasculares das artérias carótidas. Métodos Trinta ratas Wistar ovariectomizadas com 250 dias de idade foram t
Rev. Bras. Ginecol. Obstet.. Publicado em: 15/08/2019
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3. Relationship between matrix metalloproteinases and the occurrence and development of ovarian cancer
Ovarian cancer is one of the most malignant genital cancers, with a high mortality rate. Many researchers have suggested that matrix metalloproteinases (MMPs) have remarkably high expression in ovarian cancer tissues. MMPs are considered to be related to the occurrence, development, invasion and metastasis of ovarian cancer. Moreover, some studies have disco
Braz J Med Biol Res. Publicado em: 18/05/2017
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4. Palmar and plantar lichen planus: a case report and review of the literature
AbstractPalmoplantar lichen planus is an uncommon dermatosis. We present a case of 38-year-old Caucasian male with a history of pruritic, scaly lesions on the right plantar foot. Physical examination revealed whitish plaques and numerous spiny hyperkeratotic papules and focal scaling. A biopsy demonstrated orthohyperkeratosis and acanthosis of the epidermis.
An. Bras. Dermatol.. Publicado em: 2015-06
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5. Expression of MMP-2 and MMP-9 in the rat trigeminal ganglion during the development of temporomandibular joint inflammation
Orofacial pain is a prevalent symptom in modern society. Some musculoskeletal orofacial pain is caused by temporomandibular disorders (TMDs). This condition has a multi-factorial etiology, including emotional factors and alteration of the masticator muscle and temporomandibular joints (TMJs). TMJ inflammation is considered to be a cause of pain in patients w
Braz J Med Biol Res. Publicado em: 18/11/2013
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6. ImunoexpressÃo de metaloproteinases 2 e 14 e do inibidor TIMP-2 no cÃncer colorretal / Immunoexpression of metalloproteinases 2 and 14 and the inhibitor TIMP-2 in colorectal cancer
O cÃncer colorretal(CCR) Ã altamente prevalente nos paÃses mais ricos e industrializados. As metaloproteinases de matriz (MMPs) sÃo importantes enzimas que facilitam a invasÃo e disseminaÃÃo do tumor em vÃrios tipos de cÃncer, inclusive o colorretal. Os inibidores teciduais de metaloproteinases (TIMPs) sÃo os principais inativadores fisiolÃgicos d
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 09/08/2012
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7. Expressão de fator de crescimento transformador Beta e inibidores teciduais de metaloproteinases 1 e 2 em próstatas caninas normais e com lesões proliferativas / Expression of tansforming growth factor B and tissue inhibitor of metalloproteianse 1 and 2 in normal canine prostates and with proliferative lessions
The canine gland has drawn interest for research due to its similarities with the human prostate and the great incidence of lesions. Moreover, the canine prostate shows high incidence of diseases. The main lesions that affect the prostate are prostatitis, benign prostatic hyperplasia (BPH), cysts and adenocarcinoma. Recently attention has been given to lesio
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 08/03/2012
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8. Expressão de fator de crescimento transformador Beta e inibidores teciduais de metaloproteinases 1 e 2 em próstatas caninas normais e com lesões proliferativas / Expression of tansforming growth factor B and tissue inhibitor of metalloproteianse 1 and 2 in normal canine prostates and with proliferative lessions
The canine gland has drawn interest for research due to its similarities with the human prostate and the great incidence of lesions. Moreover, the canine prostate shows high incidence of diseases. The main lesions that affect the prostate are prostatitis, benign prostatic hyperplasia (BPH), cysts and adenocarcinoma. Recently attention has been given to lesio
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 08/03/2012
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9. Papel de TGFβ-1 na regulação da expressão de MMPs seus inibidores (TIMPs e Reck) em modelo de carcinoma mamário humano: análise funcional de RECK e sua correlação com dados clínico-patológicos / Role of TGFβ-1 as a common regulator of MMPs and their inhibitors (TIMPs e RECK) in human breast cancer cell model: functional analysis of RECK and its correlation with clinical-pathological
The metastatic disease is the main mortality cause of breast cancer patients. The metastatic process involves a complex cascade of events, including the organized breakdown of the extracellular matrix (ECM) compounds. The degradation of ECM is tightly regulated by the balance between the activities of matrix metalloproteinases (MMPs) and their inhibitors, th
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 14/10/2011
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10. ImunoexpressÃo de metaloproteinases 2 e 14 e do inibidor TIMP-2 no cÃncer gÃstrico dos tipos intestinal e difuso / Immunoexpression of metalloproteinases 2 and 14 and the inhibitor TIMP-2 in gastric cancer of intestinal and diffuse types
As metaloproteinases-2 (MMP-2) e -14 (MMP-14) e o inibidor tecidual de metaloproteinases tipo 2 (TIMP-2) participam de modo fundamental na transiÃÃo epitelial-mesenquimal e progressÃo tumoral-linfonodal de muitos tipos de cÃncer, inclusive o gÃstrico. O objetivo deste trabalho à avaliar a expressÃo das trÃs enzimas no carcinoma gÃstrico e metÃstase
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 15/06/2011
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11. Modulação androgênica das metaloproteinases de matriz e dos receptores de estrógeno na próstata masculina e feminina de gerbilos / Androgenic modulation of matrix metalloproteinases and estrogen receptors in the gerbil male and female prostates
O presente trabalho teve por objetivos: 1) Avaliar a atividade das MMPs na próstata de gerbilos machos e fêmeas adultos intactos, procurando comparar a glândula prostática de machos e fêmeas nas diferentes fases do ciclo estral (artigo I); 2) Avaliar o efeito da testosterona sobre o lobo ventral masculino e sobre a próstata feminina quanto à localiza�
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 17/12/2010
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12. Efeitos da doxazosina e da combinação doxasina mais finasterida sobre a interação parenquina-estroma na prostata de rato : proliferação, morte celular, atividade das MMPs-2 e 9 e expressão genica dos TIMPs 1 e 2 / Effects of doxazosin, or their combination ont th parenquimal-stromal interaction in the rat prostate : cellular proliferation and death, MMP-2 and 9 activity and TIMPs-1 and 2 gene expression
Finasteride (Fin), an inhibitor of type II 5-a reductase, and Doxazosin (Dox), an a1- adrenergic blocker, have been widely used in treatment of Benign Prostate Hyperplasia (BPH) symptoms. Recently, clinical data have demonstrated that the combined therapy with Fin+Dox reduced the long-term risk of acute urinary retention and the need for invasive therapies t
Publicado em: 2009