Thyroid Neoplasm
Mostrando 13-24 de 28 artigos, teses e dissertações.
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13. GLUT1 expression in malignant tumors and its use as an immunodiagnostic marker
OBJECTIVE: To analyze glucose transporter 1 expression patterns in malignant tumors of various cell types and evaluate their diagnostic value by immunohistochemistry. INTRODUCTION: Glucose is the major source of energy for cells, and glucose transporter 1 is the most common glucose transporter in humans. Glucose transporter 1 is aberrantly expressed in sever
Clinics. Publicado em: 2011
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14. Acurácia da ultrassonografia com Doppler colorido na identificação de doença maligna em neoplasias foliculares da tireoide. / Accuracy of color Doppler ultrasonography to identify malignancies in thyroid follicular neoplasms.
Contexto. A diferenciação entre os nódulos benignos e malignos da tireoide é possível na maioria das vezes pela citologia, obtida por punção aspirativa com agulha fina (PAAF). No caso das neoplasias foliculares (NFs), é necessária a remoção cirúrgica de ao menos parte da glândula, pois somente a análise histológica da peça permite diferenciar
Publicado em: 2010
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15. Diagnóstico de lesões da tireóide pela espectroscopia de absorção no infravermelho por transformada de Fourier-FTIR / Thyroid lesions diagnosis by fourier transformed infrared absorption spectroscopy (FTIR)
Thyroid nodules are a common disorder, with 4-7% of incidence in the Brazilian population. Although the fine needle aspiration (FNA) is an accurate method for thyroid tumors diagnosis, the discrimination between benign and malignant neoplasm is currently not possible in some cases with high incidence of false negative diagnosis, leading to a surgical interve
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 11/12/2009
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16. Analise da expressão do gene BRAF e suas possiveis implicações diagnosticas e prognosticas para pacientes portadores de carcinoma papilifero da tireoide / BRAF expression may help identify malignant nodules and define outcomes in papillary thyroid cancer patients
Background: Thyroid cancer is the most common endocrine malignancy, corresponding to 1% of all human neoplasms. Thyroid nodules are very frequent, mainly in women over 60 years. The relationship of BRAF gene with papillary thyroid tumorigenesis is well recognized in the literature. Its BRAFV600E mutation has been related to tumor aggressiveness and patients�
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 31/08/2009
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17. Investigation of clinical utility of ATM and PTEN genes in the differentiated thyroid cancer / Avaliação da utilidade clinica dos genes ATM e PTEN em cancer bem diferenciado da tireoide
In order to investigate the clinical utility of two tumor-suppressing genes involved in the control of cell proliferation and survival, we ve studied proteins ATM and PTEN through immunohistochemistry in 272 differentiated thyroid carcinoma diagnosed patients (142 classical papillary thyroid carcinomas type, 72 papillary thyroid carcinomas follicular variant
Publicado em: 2009
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18. "Predição do risco de metástase do carcinoma bem diferenciado da glândula tireóide pela quantificação digital da imunoexpressão da galectina-3 nos compartimentos do tireócito maligno" / Prediction of metastasis risk in well-differentiated thyroid carcinoma based on digital quantification of galectin-3 immunoexpression in subcellular compartments of the malignant thyrocyte
INTRODUCTON: Papillary and follicular carcinomas are primary malignant neoplasias of the thyroid gland and are classified as well-differentiated carcinoma. In these cases, determination of individual risk of metastasis allows offering an adequate treatment. Nowadays therapy is chosen based on classification according to prognostic factors and biomarkers can
Publicado em: 2006
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19. Lack of mutations of exon 2 of the MEN1 gene in endocrine and nonendocrine sporadic tumors
In addition to the mutations that underlie most cases of the multiple endocrine neoplasia type 1 (MEN1) syndrome, somatic mutations of the MEN1 gene have also been described in sporadic tumors like gastrinomas, insulinomas and bronchial carcinoid neoplasm. We examined exon 2 of this gene, where most of the mutations have been described, in 148 endocrine and
Brazilian Journal of Medical and Biological Research. Publicado em: 2001-07
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20. Secondary neoplasm of the thyroid presenting as a goitre
Secondary neoplasm is a very rare finding in a goitre despite the numerous reports of metastatic deposits in the thyroid gland at necropsy. Eleven cases are reported of such deposits presenting clinically as a thyroid nodule, the sites of origin including a meningioma and an unusual carcinoma of the skin. Some of the factors, including pre-existent degenerat
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21. Thyroid carcinoma and hyperthyroidism in a dog
A 10-year old spayed, female Labrador retriever, with an 8-month history of weight loss, increased heart rate, and hyperactivity, was diagnosed with hyperthyroidism and a thyroid neoplasm. Thyrotoxic heart disease is documented in this case.
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22. Mucin producing microfollicular adenoma of the thyroid.
An unusual case of a mucin secreting benign microfollicular adenoma of the thyroid in a 30 year old euthyroid woman is reported. Histologically, the lesion was characterised by follicular cells with the appearance of signet ring cells. Histochemistry showed the mucin content of these cells to consist uniformly of sulphated acid mucins; positive thyroglobulin
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23. Characterization of the Immunochemical Forms of Calcitonin Released by a Medullary Thyroid Carcinoma in Tissue Culture
Immunoreactive calcitonin released by a medullary thyroid carcinoma in tissue culture has been found to exhibit heterogeneity when analyzed by gel chromatography and radioimmunoassay, in a pattern analogous to that seen in the circulation of the patient from whom the neoplasm was removed. To examine the cause of the heterogeneity, the immunoreactive material
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24. Medullary carcinoma of the thyroid with carcinoid-like features.
AIMS: To show that medullary carcinomas of the thyroid are morphologically indistinguishable from gut carcinoids: the value of histochemistry in their identification and differential diagnosis from metastatic carcinoid tumours to the thyroid and some follicular cell neoplasms. METHODS: 15 thyroid medullary carcinomas with features of gut carcinoids were hist