Therapeutical Use
Mostrando 1-12 de 55 artigos, teses e dissertações.
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1. Protein PEGylation for the design of biobetters: from reaction to purification processes
The covalent attachment of polyethylene glycol (PEG) to therapeutical proteins is an important route to develop biobetters for biomedical, biotech and pharmaceutical industries. PEG conjugation can shield antigenic epitopes of the protein, reduce degradation by proteolytic enzymes, enhance long-term stability and maintain or even improve pharmacokinetic and
Braz. J. Pharm. Sci.. Publicado em: 08/11/2018
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2. Synergistic antifungal activity of the lipophilic fraction of Hypericum carinatum and fluconazole
ABSTRACT Hypericum species, Hypericaceae, are recognized as a source of therapeutical agents. Purified fractions and isolated compounds have been shown antimicrobial activity. As the indiscriminate use of antifungals and the increase of infections caused by emerging species are leading to the search of new alternative treatments, the aim of this study was to
Rev. bras. farmacogn.. Publicado em: 2017-02
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3. Use of the inverted “T” incision to approach a plantar nodular lesion
Knowledge of the inverted "T" incision - used in plastic, oncologic and orthopedic surgery - has allowed its adaptation for the diagnostic assessment and therapeutical approach of acral, nodular lesions. The authors describe the use of this technique for the surgical approach of a patient with a pla
An. Bras. Dermatol.. Publicado em: 2015-02
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4. Estudos de QSAR 2D baseados em descritores topológicos e fragmentos moleculares para uma série de derivados azólicos ativos contra Candida albicans
Azole derivatives are the main therapeutical resource against Candida albicans infection in immunocompromised patients. Nevertheless, the widespread use of azoles has led to reduced effectiveness and selection of resistant strains. In order to guide the development of novel antifungal drugs, 2D-QSAR models based on topological descriptors or molecular fragme
Química Nova. Publicado em: 2012
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5. Automedicação em idosos: estudo SABE / Self-medication in the elderly: SABE study
A automedicação retrata o princípio do próprio indivíduo buscar espontaneamente por algum medicamento, que considere adequado para resolver um problema de saúde. Esta prática, ainda, é pouco explorada em idosos, principalmente a partir de dados populacionais. Desse modo, o objetivo do presente estudo foi analisar a pratica de automedicação em idoso
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 03/10/2011
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6. Obtenção de membranas hidrofílicas a base de PVP (Poli N-vinil-2-pirrolidona) contendo alginato de sódio e nanocarga de pseudoboemita obtida pelo processo sol-gel
The use of hydrogels combined with various additives in tissue regeneration and wound scarring, injuries and burnings has been an option in treatments of difficult scarring, infected-bleeding wounds, burnings and other diseases whose treatments, moist and sterilized resources are required. The hydrogels based on poly (N-vinyl-2-pyrrolidone) are membranes tha
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 03/03/2011
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7. Avaliação dos efeitos do ultrassom terapêutico sobre a cafeína e verificação da liberação em sistema de difusão vertical
Currently, the physiotherapists use the phonoforesis, which consists in the therapeutical ultrasound (US) used to increase the drug molecules migration through the skin, however, the US can shows oxidative effects, and is used, for example, in chemical reactions acceleration. The present study aimed to perform the electrochemical evaluation and the diffusion
Química Nova. Publicado em: 2011-09
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8. AVALIACAO DA SAUDE CARDIOVASCULAR E DE QUALIDADE DE VIDA EM IDOSOS DE FORTALEZA-CEARA / Assessment of cardiovascular health and quality of life in elderly individuals in Fortaleza-Ceara.
Cardiovascular diseases, so common in elderly people with hypertension an important health risk, call for the adoption of preventive measures and drug therapies and nonpharmacological. The objective was to examine the relationship between cardiovascular health and quality of life of elderly hypertensive patients in Fortaleza, Ceara. The study was a descripti
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 27/02/2010
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9. Sofrimento psiquico grave de adolescentes em privação de liberdade : um estudo exploratório
This study had the objective to systemize the main psycho-social and socio-educational aspects that related with the psychic suffering of adolescents in conflict of law and freedom privation. This research wanted to verify the signals and symptoms identified trough themselves perceptions related on their condition of health/insanity. In similar way, it was o
Publicado em: 2010
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10. Therapeutic Itineraries of individuals with problems in consequence of the use of alcohol in a psychosocial care center / Itinerários terapêuticos de sujeitos com problemáticas decorrentes do uso de álcool em um centro de atenção psicossocial
Os problemas decorrentes do uso de álcool trazem impactos relevantes para o campo da saúde pública e levam ao desenvolvimento de políticas e propostas de tratamento baseadas em perspectivas e abordagens teórico-práticas que apresentam marcantes diferenças entre si, o que resulta na pluralidade de ofertas terapêuticas atuais. Tratase de questão compl
Publicado em: 2010
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11. Fatores associados ao uso de psicotrópicos em idosos no município de São Paulo: estudo SABE / Risk factors associated to the use of psychotropic Drugs in the elderly in São Paulo City: SABE study
Nos últimos anos, o uso dos psicotrópicos em idosos, aumentou expressivamente em decorrência da ampliação das indicações terapêuticas dessa classe, do lançamento de agentes com menor perfil de toxicidade e do reconhecimento de que determinados quadros clínicos, prevalentes nessa faixa etária, podem ser tratados com esses medicamentos. Todavia, o u
Publicado em: 2010
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12. Estudo da biodistribuição e biocompatibilidade de nanopartículas magnéticas à base de maguemita recobertas com DMSA em macacos-prego (Cebus spp.) juvenis mediante análise morfológica
It is essential to determine the biodistribution and biocompatibility of magnetic nanoparticles (MNPs) for in vivo biomedical applications in order to ensure their safe clinical use. Biodistribution of MNPs depends on their properties, such as surface characteristics, size, shape and charge, which can all affect biodistribution, clearance, particle-cell inte
Publicado em: 2009