Teratogenic
Mostrando 13-24 de 108 artigos, teses e dissertações.
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13. Biodegradação de alcoóis, ftalatos e adipatos em um solo tropical contaminado
The adipic and phthalic acid esters are plasticizers, have low water solubility, high partition octanol/water coefficients (Kow) and accumulate in soil and sediments. These compounds are considered teratogenic, carcinogenic and endocrine disruptors chemicals. This study evaluated the bioremediation of tropical soil contaminated with plasticizers process wast
Química Nova. Publicado em: 2010
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14. Efeitos de extratos de Nierembergia veitchii (Hook) Solanaceae sobre a fertilidade de ratas e morfologia óssea dos fetos / The effects of Nierembergia veitchii (Hook) Solanaceae extracts in rat fertility and fetal skeleton morphology
Os efeitos da administração oral dos extratos aquoso (NvH2O), metanólico (NvmeOH), butanólico (Nvbut) e hexano (Nvhex), obtidos, seqüencialmente, de 500g de Nierembergia veitchii (planta seca), foram comparados aos obtidos com vitamina D3 (2,5mg.kg-1) e aos de um grupo controle (solução fisiológica - SF), quando administrados, durante todo o período
Publicado em: 2010
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15. Diverse uses of feathers with emphasis on diagnosis of avian viral infections and vaccine virus monitoring
The large amounts of feathers produced by the poultry industry, that is considered as a waste was explored for possible uses in various industries, such as meals for animals, biofuels, biodegradable plastic materials, combating water pollution and more. That review mentions these uses, but concentrate on the utilization of feathers for the diagnosis of viral
Revista Brasileira de Ciência Avícola. Publicado em: 2009-09
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16. Malformações e morte embrionária em ruminantes causadas pela ingestão de Mimosa tenuiflora (jurema preta) / Embryonic death and malformations in ruminants caused by the ingestion of Mimosa tenuiflora (jurema preta).
Malformations caused by the ingestion of Mimosa tenuiflora have been reported in sheep, goats and cattle in the semiarid of the Brazilian Northeastern. This paper reports malformations diagnosed in ruminants, from 2000 to 2008, by the Federal University of Campina Grande in Patos, State of Paraíba. During the period 47 (3.48%) out of 1.347 ascensions were d
Publicado em: 2009
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17. Mulheres alcoolistas: histórico reprodutivo e alterações do crescimento e desenvolvimento dos filhos
Alcohol is the most used teratogenic substance in the west world and its use during pregnancy, from moderate to severe, is a serious problem to public health due to the risks that it might bring to the mother (increases the risks for spontaneous abortions and premature detachment of the placenta) and to the fetus (physical, mental and behaviour damage and/or
Publicado em: 2009
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18. Avaliação da toxicidade da Ipomoea carnea em caprinos durante o período perinatal: estudos de neuroteratologia / Evaluation of the toxicity of Ipomoea carnea in goats during postnatal period
Ipomoea carnea, a shrub plant, is a toxic plant largely distributed throughout Brazil and others topical countries. This plant possess swainsonine, an indolizidinic alkaloid as the most important active toxic principle, which promotes cellular accumulation of not metabolized oligossacarides, due to inhibition of acid or lisossomal αmanosidasis enzyme,
Publicado em: 2009
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19. AVALIAÇÃO DE NOVOS ANÁLOGOS DA TALIDOMIDA QUANTO A INIBIÇÃO DA PRODUÇÃO DE ÓXIDO NÍTRICO, CITOCINAS PRÓ-INFLAMATÓRIAS E EXPRESSÃO DE CD80 E CD86 EM MACRÓFAGOS
Thalidomide is used to treat various diseases including erythema nodosum leprosum (ENL), an inflammatory complication of leprosy. However, it has severe teratogenic activity and novel thalidomide analogues might be used to treat the disease without this severe side effect. A series of diamine compounds containing two hydrolyzed phthalimido structures were ch
Publicado em: 2009
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20. DESENVOLVIMENTO E VALIDAÇÃO DE MÉTODO PARA DETERMINAÇÃO DE ETILENOTIOURÉIA EM URINA EMPREGANDO HPLCUV / DEVELOPMENT AND VALIDATION METHOD FOR THE DETERMINATION OF ETHYLENETHIOUREA IN URINE BY HPLC-UV
In order to supply the world-wilde demand for food, it is essential to use the pesticides to protect the crops against pests and diseases. But the indiscriminate and injudicious use of these compounds have resulted in widespread contamination in food commodities and environment in all fields, increasing, this way, the preoccupation with chemical products use
Publicado em: 2008
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21. A model for prenatal toxicological studies in ruminants: evaluation of toxic effects caused by Senna occidentalis in goats / Proposta de modelo para o estudo de toxicologia perinatal em ruminantes: avaliação dos efeitos tóxicos da Senna occidentalis em caprinos
Senna occidentalis (So - formerly Cassia occidentalis), Fabaceae-Caesalpinoideae (Leguminosae) is a weed growing in pastures and in cultivated fields such as corn and soybeans in many tropical and subtropical areas worldwide. Many reports have shown that So is toxic to different animal species. Histologic lesions plant-related are degeneration skeltal and ca
Publicado em: 2008
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22. Double-blind trial of the efficacy of pentoxifylline vs thalidomide for the treatment of type II reaction in leprosy
Type II reaction in leprosy, or erythema nodosum leprosum (ENL), is often characterized by severe clinical symptoms together with nerve function impairment leading to permanent disabilities. Thalidomide has been shown to be a highly effective drug for the treatment of ENL. It is, however, contraindicated for women of childbearing age due to its teratogenicit
Brazilian Journal of Medical and Biological Research. Publicado em: 13/02/2007
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23. Desenvolvimento embrionário em ratas wistar prenhes submetidas ao ultra-som terapêutico de 3 MHz
Therapeutic ultrasound is widely used in different aesthetic treatment by young women, who can be irradiated during early gestation. Researches regarding the effects of therapeutic ultrasound on gestation present controversial results. Methodologies incompatible with clinical aspects are used and different methods and technics were employed. However none of
Publicado em: 2007
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24. Etanol, deficiência de ácido fólico e associação desses dois fatores durante a gestação de camundongos swiss / Etanol, Deficiency of Acid Fólico and Association Of these Two Factors During the Gestation of Swiss Mice
In spite of the well known teratogenic effect of ethanol, it is still the most consumed exogenous abuse substance by women of reproductive age. Ethanol also impairs the absorption, transport and metabolism of folic acid. The aim of this study was to investigate the effects of ethanol, dietary deficiency of folic acid and the association of both on the outcom
Publicado em: 2007