Synthetic Phosphoethanolamine
Mostrando 1-8 de 8 artigos, teses e dissertações.
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1. Synthetic phosphoethanolamine: the state of the art of scientific production
ABSTRACT Cancer is a multifactorial disease and a serious public health problem. Currently, alternative drug treatments for cancer are actively being sought, which is the case of synthetic phosphoethanolamine (PHOS-S), a compound that could possibly have anticarcinogenic effects. To analyze the available scientific evidence to evaluate the anticarcinogenic e
Braz. J. Pharm. Sci.. Publicado em: 09/04/2018
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2. Atividade da fosfoetanolamina sintética em melanoma murino experimental / Activity of synthetic phosphoethanolamine in experimental murine melanoma
The low responsiveness of melanoma to traditional treatments together with its increasing incidence makes the development of new therapeutic strategies against this type of cancer extremely important. In this study, we used a murine melanoma model to evaluate the effects of synthetic phosphoethanolamine (PEA) on the development of this tumor. In vitro, PEA h
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 06/11/2012
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3. The effect of phosphoethanolamine intake on mortality and macrophage activity in mice with solid ehrlich tumors
The aim of the present study was to examine the effect of a diet rich in synthetic PEtn on the metabolism macrophages of tumor-bearing mice. The results demonstrated that PEtn increased the animals' survival time. In addition, the treated animals released smaller amounts of hydrogen peroxide (H2O2) and nitric oxide (NO) than the non-treated animals, particul
Brazilian Archives of Biology and Technology. Publicado em: 2011-12
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4. Application pre-clinic of synthetic phosphoethanolamine on epilepsies experimental models / Aplicação pré-clínica da fosfoetanolamina sintética sobre modelos experimentais de epilepsias
A fosfoetanolamina é um dos principais constituintes de membranas neuronais de mamíferos e sua deficiência orgânica está intensamente relacionada com epilepsias e distúrbios do sistema nervoso central. Devido a estas evidências, é de suma importância o conhecimento da influência das propriedades físico-químicas, na forma sólida e líquida e suas
Publicado em: 2007
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5. Efeitos antiproliferativos e apoptóticos da fosfoetanolamina sintética no melanoma B16F10 / Effects antiproliferation and apoptotic of the synthetic phosphoethanolamine in melanoma B16F10
A fosfoetanolamina sintética é uma molécula fosforilada artificialmente, com síntese inédita realizada pela primeira vez pelo nosso grupo, diferindo-se das moléculas atuais pelo seu nível de absorção de aproximadamente 90%, com diversas propriedades antiinflamatórias e apoptóticas. O objetivo principal desse estudo e avaliar os efeitos antitumorai
Publicado em: 2007
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6. Phosphatidylcholine Synthesis Influences the Diacylglycerol Homeostasis Required for Sec14p-dependent Golgi Function and Cell Growth
Phosphatidylcholine and phosphatidylethanolamine are the most abundant phospholipids in eukaryotic cells and thus have major roles in the formation and maintenance of vesicular membranes. In yeast, diacylglycerol accepts a phosphocholine moiety through a CPT1-derived cholinephosphotransferase activity to directly synthesize phosphatidylcholine. EPT1-der
The American Society for Cell Biology.
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7. Meningococcal lipopolysaccharides: virulence factor and potential vaccine component.
Lipopolysaccharides (LPS) are surface components of the outer membrane of Neisseria meningitidis. Today, 12 different types of meningococcal LPS (immunotypes) are known, of which 3 are prevalent in the western world. The differences between these immunotypes are in the oligosaccharide part of the LPS molecule and consist of small differences in the oligosacc
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8. Minimal oligosaccharide structures required for induction of immune responses against meningococcal immunotype L1, L2, and L3,7,9 lipopolysaccharides determined by using synthetic oligosaccharide-protein conjugates.
The 12 types of meningococcal lipopolysaccharide (LPS) (immunotypes) contain immunotype-specific and cross-reactive epitopes situated on the oligosaccharide part of the LPS molecules. To identify useful cross-reactive epitopes and to determine minimal oligosaccharide structures required for the induction of an immune response against the most prevalent immun