Supramolecular Assembling
Mostrando 1-12 de 14 artigos, teses e dissertações.
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1. Dextran Sulfate/Pramlintide Polyelectrolyte Nanoparticles as a Promising Delivery System: Optimization, Evaluation of Supramolecular Interactions and Effect on Conformational Stability of the Peptide Drug
In this study, we investigated the feasibility to obtain nanoparticles (NPs) by assembling pramlintide (Pram) with dextran sulfate (DexS), as a new approach for mucosal peptide delivery. DexS/Pram NPs were prepared by dropwise addition of a Pram solution to a DexS solution under magnetic stirring. The physicochemical characteristics of NPs and molecular inte
J. Braz. Chem. Soc.. Publicado em: 2021-08
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2. Síntese e caracterização de iodetos de diteluroéteres Análise da estrutura supramolecular / Synthesis and characterization of ditelluroethers iodides Analysis of supramolecular structure
Este trabalho apresenta a síntese e caracterização de treze novos compostos pertencentes à classe dos iodetos de diteluroéteres. Os reagentes de partida (diteluroéteres) foram sintetizados por uma metodologia até então pouco citada na literatura para a síntese dessa classe de compostos. Essa metodologia mostrou-se eficiente uma vez que foram sinteti
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 28/02/2012
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3. Estudo de Filmes Automontados de látex de borracha natural, Carboximetil-quitosana e nanopartículas magnéticas / Study of Self-Assembling Films of Natural Rubber Latex, carboxymethyl chitosan and magnetic nanoparticles
In this work, we investigated the fabrication of ultrathin films of natural rubber latex (NRL), carboxymethyl-chitosan (CMC) and magnetite (Fe3O4) nanoparticles (MNP) in different supramolecular architectures. The materials choice was based on the mechanical properties and biocompatibility of NRL, antimicrobial action of CMC and magnetic properties of MNP, w
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 17/11/2010
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4. SÍNTESE, ESTUDOS ESPECTROSCÓPICOS E ESTRUTURAIS DE COMPLEXOS CONTENDO O LIGANTE 4,4- BIPIRIDINA, O ÂNION BARBITURATO E OS ÍONS METÁLICOS DA PRIMEIRA SÉRIE DE TRANSIÇÃO (Fe2+, Co2+, Ni2+, Cu2+ e Zn2+)
This work describes the synthesis and characterization of five new transition metal complexes of general formula MB2Bipy.10H2O (where M = Fe2+, Co2+, Ni2+, Cu2+ and Zn2+, B is barbiturate anion and Bipy is 4,4-bipyridine) . Several physical and spectroscopical techniques were used to characterize the compounds, such as elemental analysis (CHN), thermal analy
Publicado em: 2009
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5. Supramolecular self-assembling of [HgII(RC6H4NNNC6H4R)2Py] [R = EtOC(O)] through reciprocal metal-η2-arene π-interactions and non classical C-H···O bonding: synthesis and X-ray characterization of a bis diaryl symmetric-substituted triazenide complex polymer of Hg(II)
1,3-bis(4-etoxicarbonilfenil)triazeno desprotonado reage com Hg(CH3COO)2 em tetraidrofurano para formar cristais amarelos de {[HgII(RC6H4NNNC6H4R)2Py]2}n [R = EtOC(O)]. Os téctons [HgII(RC6H4NNNC6H4R)2Py] encontram-se ligados aos pares como dímeros centro simétricos por meio de interações π recíprocas do tipo metal-η2-areno. As unidades dímeras rela
Journal of the Brazilian Chemical Society. Publicado em: 2008
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6. Phase equilibrium and structural characterizarion of systems composed by polyanions and cationic surfactants / Equilibrio de fases e caracterização estrutural de sistemas contendo polianions e surfatantes cationicos
Polieletrólitos associam-se fortemente com surfatantes de carga oposta em meio aquoso, levando a uma separação de fases que resulta em uma fase concentrada, rica em polieletrólito e surfatante, em equilíbrio com uma fase diluída constituída pelos contra-íons. A fase concentrada pode ser constituída de interessantes estruturas supramoleculares advind
Publicado em: 2008
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7. Nanoagregados baseados em ciclodextrinas em associação com a tetraciclina: caracterização fisico-química e avaliação antimicrobiana
Molecular self-assembling has been shown to be an efficient method to produce structures of few hundreds of nanometers in size. The supramolecular compounds made from (R)- cyclodextrin:tetracycline in aqueous solution were evaluated. The physicochemical interactions between â-cyclodextrin:tetracycline were characterized by dynamic light scattering (DLS), is
Publicado em: 2007
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8. Extending supramolecular fullerene-porphyrin chemistry to pillared metal-organic frameworks
Porphyrins and fullerenes are spontaneously attracted to each other. This supramolecular recognition element can be exploited to produce ordered arrays of interleaved porphyrins and fullerenes. C60⋅H2TpyP⋅Pb(NO3)2⋅1.5TCE (H2TpyP = tetra-4-pyridylporphyrin; TCE = 1,1,2,2-tetrachloroethane) crystallizes in the tetragonal P4/n space group and the structur
National Academy of Sciences.
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9. Peptide-amphiphile nanofibers: A versatile scaffold for the preparation of self-assembling materials
Twelve derivatives of peptide-amphiphile molecules, designed to self-assemble into nanofibers, are described. The scope of amino acid selection and alkyl tail modification in the peptide-amphiphile molecules are investigated, yielding nanofibers varying in morphology, surface chemistry, and potential bioactivity. The results demonstrate the chemically versat
National Academy of Sciences.
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10. Virus-sized self-assembling lamellar complexes between plasmid DNA and cationic micelles promote gene transfer
Gene therapy is based on the vectorization of genes to target cells and their subsequent expression. Cationic amphiphile-mediated delivery of plasmid DNA is the nonviral gene transfer method most often used. We examined the supramolecular structure of lipopolyamine/plasmid DNA complexes under various condensing conditions. Plasmid DNA complexation with lipop
The National Academy of Sciences of the USA.
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11. Negatively charged self-assembling DNA/poloxamine nanospheres for in vivo gene transfer
Over the past decade, numerous nonviral cationic vectors have been synthesized. They share a high density of positive charges and efficiency for gene transfer in vitro. However, their positively charged surface causes instability in body fluids and cytotoxicity, thereby limiting their efficacy in vivo. Therefore, there is a need for developing alternative mo
Oxford University Press.
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12. Idiotypic mimicry and the assembly of a supramolecular structure: an anti-idiotypic antibody that mimics taxol in its tubulin-microtubule interactions.
Taxol, originally extracted from the bark of the western yew, Taxus brevifolia, is reportedly the first of a new class of anti-cancer agents. It acts by promoting and irreversibly stabilizing microtubule assembly, thus interfering with the dynamic processes required for cell viability and multiplication. With the aim of using immunological techniques to stud