Stereoisomers
Mostrando 1-12 de 96 artigos, teses e dissertações.
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1. Synthesis, in silico Study, Theoretical Stereochemistry Elucidation and Antifungal Activity of New Imides Derived from Safrole
Ten imides derived from safrole, 4a-4j, were synthesized and their structures were fully characterized by infrared (IR) spectroscopy, 1H and 13C nuclear magnetic resonance (NMR) spectroscopy and high resolution mass spectrometry (HRMS) analysis. Among the ten imides studied, eight are new. The compounds were evaluated in an in silico study and showed strong
J. Braz. Chem. Soc.. Publicado em: 2020-10
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2. Structure and Absolute Configuration of Secondary Metabolites from Two Strains of Streptomyces chartreusis Associated with Attine Ants
The antibiotic streptazolin (1), its E-isomer (2), along with the stereoisomers strepchazolin A (3) and strepchazolin B (4) and the inorganic compound cyclooctasulfur (5) were produced in solid culture by Streptomyces chartreusis ICBG377, which was isolated from the fungal garden of the leaf-cutter ant Acromyrmex subterraneus brunneus. This is the first time
J. Braz. Chem. Soc.. Publicado em: 24/10/2019
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3. Absolute Configuration of Solenopsis Piperidines is a Tool to Classify Fire Ants (Formicidae:Myrmicinae)
Piperidine alkaloids are predominant in ant venom glands of S. invicta and S. saevissima. These ants are broadly sympatric in Southeastern Brazil, and potentially diagnostic compounds could assist in ant identification. We determined the absolute configuration of 2,6-dialkyl-piperidines of S. invicta and S. saevissima workers and used these data to group Sou
J. Braz. Chem. Soc.. Publicado em: 2018-02
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4. Synthesis of Organotin Substituted Tricyclic Macrodiolides
The radical addition of triorganotin hydrides, R3SnH (R =n-butyl, phenyl, neophyltin), to four unsaturated diesters of (11R,12R)-9,10-dihydro-9,10-ethaneanthracene-11,12-dimethanol leads to products of cyclohydrostannation with an average yield of around 80%. Whereas the addition of these hydrides to diacrylate and dimethacrylate leads to the expected mixtur
J. Braz. Chem. Soc.. Publicado em: 2016-03
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5. Cromatografia gasosa quiral na resolução de enantiômeros envolvidos em flavours de frutas
This work addresses the use of chiral gas chromatography in resolving optically active stereoisomers and racemates found in fruit flavours. It presents the types of chiral selectors applied to terpene-derived metal coordination compounds, polysiloxane-linked α-amino acid and mixed chiral stationary phases, and focuses on derivatized cyclodextrins, the most
Quím. Nova. Publicado em: 2014
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6. Estudo qualitativo e quantitativo de biomarcadores ácidos e hidrocarbonetos presentes em óleos da Bacia Potiguar / Qualitative and quantitative study of acidic and hydrocarbon biomarkers of oil from the Potiguar Basin
rabalho foram sintetizados quatro biomarcadores ácidos, a saber: ácido 5b (H) colânico (2), 5a (H) homopregnânico (4), 8,13-tetraidrocopálico (6) e 15-isocopálico (7). Para tanto, foram utilizadas matérias primas comerciais (ácido litocólico e estigmasterol) e o ácido copálico (extraído e purificado a partir de bálsamo de copaíba). Também foi
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 07/12/2011
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7. Influência do diabetes mellitus gestacional na disposição cinética e metabolismo estereosseletivos do labetalol em pacientes com hipertensão arterial / Influence of gestational diabetes mellitus on the kinetic disposition and stereoselective metabolism of labetalol in patients with arterial hypertension,
Labetalol, a hypertensive agent considered to be safe for use by pregnant women, is clinically available as a mixture of two racemates, with the (R,R) isomer being a antagonist and the (S,R) isomer being responsible for the blocking activity. The study investigated the influence of gestational diabetes mellitus (GDM) on the kinetic disposition and stereosele
Publicado em: 2009
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8. SÃntese assimÃtrica de 3-carboxamidas enantiomericamente puras e de hidrazidas e arilhidrazonas, derivadas do novo heterociclo 7-(benzoil)- 2-isoxazolina[5,4-b] pirrolidina. AvaliaÃÃo das atividades biolÃgicas
In our previous studies, aza-bicyclic 2-isoxazolines were obtained, such as, 2- isoxazoline[5,4-b] piperidine and 2-isoxazoline[5,4-b] pyrrolidine. N-(benzoyl)-amides and, derived from these heterocycles, showed promising biological activity, (anti-inflammatory and toxicity). Compounds containing hydrazide and hydrazone functionalities are described in the l
Publicado em: 2008
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9. Biotransformação de compostos funcionalizados por fungos basidiomicetos e desmetilação/desalquilação de aminas terciárias por fungos Aspergillus terreus / Biotransformation of Compounds Functionalized by Basiodiomycetes Fungi and Demethylation/dealkylation of Tertiary Amines by Aspergillus terreus.
In this work was considered the selectivity of reactions biocatalysted by basidiomycetes fungi with bifuncionalized compounds with ketone and selenide groups (1-2) or ketone and thio groups (3-4). The compounds 1-4 were prepared in according with methodologies from literature. During the synthesis of standard racemic β-hydroxyselenides 1a-4a and β-
Publicado em: 2007
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10. Chemical ecology of insect and Piperaceae species / Ecologia química de insetos e espécies de Piperaceae
The study was presented in six chapters that included several aspects of chemical ecology of insects and Piperaceae species as following: The Chapter 1 describes taxonomical aspects, natural history of the insects and field observation and the organization of hosts Piperaceae according to the observed feeding preferences of the associated insects. It was obs
Publicado em: 2006
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11. Redução eletroquímica de cinamatos de metila orto-substituídos / Electrochemical reduction of ortho-substituted methyl cinnamates
The synthesis and electrochemical reduction in DMF of some ring substituted cinnamic esters are described. The main objective if this work is to verify the influence of the substituents on the electrohydrodimerization (EHD). The substrates studied were the methyl esters of o-methyl- (1), o-chloro- (2), o-nitro- (3), m,p-dichloro- (4), m-chloro- (5), p-chloro
Publicado em: 2004
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12. Estudo cinetico e de equilibrio na separação cromatografica dos enantiomeros da cetamina em triacetato de celulose microcristalina
There is a growing demand for efficient and low cost methods for the purification of the stereoisomers from chiral molecules, named enantiomers, in the manufacturing of drugs, flavours, pesticides and food additives, where these compounds are commonly encountered. Chrornatographic method is considered in nowadays an important alternative for the production o
Publicado em: 2003