Splenomegaly
Mostrando 1-12 de 313 artigos, teses e dissertações.
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1. Lysosomal acid lipase deficiency in pediatric patients: a scoping review
Abstract Objective: Lysosomal acid lipase deficiency (LAL-D) is an underdiagnosed autosomal recessive disease with onset between the first years of life and adulthood. Early diagnosis is crucial for effective therapy and long-term survival. The objective of this article is to recognize warning signs among the clinical and laboratory characteristics of LAL-D
Jornal de Pediatria. Publicado em: 2022
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2. Association of FOXO3 polymorphism (rs3800231) and clinical subphenotypes of beta thalassemic individuals
Abstract Introduction Studies have shown that the loss of the FOXO3 transcriptional function is involved in the pathophysiology of some chronic erythroid disorders, including beta-thalassemia (β-thal). Therefore, the single nucleotide polymorphism (SNP) rs3800231 (35-2764A > G) could contribute to alterations in its transcriptional activity, acting as a mo
Hematology, Transfusion and Cell Therapy. Publicado em: 2022
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3. The relevance of a bank with genotyped platelets donors
ABSTRACT Objective: Describe the clinical and laboratory characteristics and the transfusion strategy of patients at Hospital Israelita Albert Einstein with platelet refractoriness and identify their etiological characteristics. Standardize the platelet immunofluorescence technique by flow cytometry as a test for platelet compatibility in immune platelet re
Hematology, Transfusion and Cell Therapy. Publicado em: 2022
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4. HIV-positive patients presenting with peripheral blood cytopenias: is bone marrow assessment a priority?
ABSTRACT Introduction: Hematologic abnormalities are frequent among persons living with HIV (PLWH). The bone marrow aspirate (BMA) and biopsy (BMB) are commonly performed in the diagnostic approach of patients with unexplained cytopenias. Changes in antiretrovirals, supportive therapy and increased life expectancy have modified the distribution and etiology
Hematology, Transfusion and Cell Therapy. Publicado em: 2022
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5. Infective Endocarditis in Childhood: a Single-Center Experience of 18 Years
Abstract Introduction: We aimed to present the risk factors, clinical and laboratory findings, treatment management, and risk factors for morbidity and mortality of infective endocarditis (IE) as well as to relate experiences at our center. Method: We retrospectively analyzed data of 47 episodes in 45 patients diagnosed with definite/possible IE according
Braz. J. Cardiovasc. Surg.. Publicado em: 2021-04
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6. Ultrasound evaluation of schistosomiasis-related morbidity among the Xakriabá people in the state of Minas Gerais, Brazil
Resumo Objetivo: Investigar a morbidade por esquistossomose na população indígena Xakriabá usando a ultrassonografia. Materiais e Métodos: Estudo de campo censitário realizado na terra da população indígena Xakriabá (166 convidados; 148 participantes; idade de 0-77). Foram feitos ultrassonografia abdominal, exame físico e coproscopia (EPF). Os t
Radiol Bras. Publicado em: 10/01/2020
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7. Use of the LI-RADS classification in patients with cirrhosis due to infection with hepatitis B, C, or D, or infected with hepatitis B and D
Resumo Objetivo: Avaliar lesões hepáticas de acordo com a classificação LI-RADS nas tomografias computadorizadas de pacientes com hepatite B, co-infectados ou não com vírus delta, e com hepatite C crõnica, e o grau de concordância entre os radiologistas. Materiais e Métodos: Foram incluídos 38 pacientes com hepatite B, co-infectados ou não com v
Radiol Bras. Publicado em: 20/12/2019
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8. Phage Therapy as an Approach to Control Salmonella enterica serotype Enteritidis Infection in Mice
Abstract INTRODUCTION: Salmonella enterica serotype Enteritidis (S. Enteritidis) is a cause of food-borne human illness. Given the prevalence of antibiotic resistance of Salmonella Enteritidis and the lack of antibiotic efficacy in future years, its replacement with other agents is necessary. One of the most useful agents is bacteriophages. METHODS S. Ente
Rev. Soc. Bras. Med. Trop.. Publicado em: 14/11/2019
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9. Lysosomal acid lipase deficiency in Brazilian children: a case series
Resumo: Objetivo: Descrever as características demográficas, clínicas, laboratoriais e moleculares de pacientes com deficiência de lipase ácida lisossomal. Métodos: Análise retrospectiva dos prontuários médicos de crianças com a deficiência de lipase ácida lisossomal. Resultados: Sete crianças com deficiência de lipase ácida lisossomal (5 M
J. Pediatr. (Rio J.). Publicado em: 28/10/2019
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10. Autoimmune hepatitis in 847 childhoodonset systemic lupus erythematosus population: a multicentric cohort study
Abstract Objective: To evaluate autoimmune hepatitis (AIH) in a multicenter cohort of childhood-onset systemic lupus erythematosus (cSLE) patients. Methods: This retrospective multicenter study included 847 patients with cSLE, performed in 10 Pediatric Rheumatology services of São Paulo state, Brazil. AIH was defined according to the International Autoimmu
Adv. rheumatol.. Publicado em: 29/07/2019
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11. Abortion in association with transplacental Theileria equi infection in a mare from the State of Espírito Santo, southeast Brazil: case report
RESUMO A piroplasmose equina é transmitida por carrapatos, sendo causada pelos protozoários Babesia caballi e Theileria equi. O objetivo deste trabalho foi relatar um caso de aborto equino associado à piroplasmose fetal. Uma égua gestante, aparentemente saudável, abortou no 10º mês de gestação. Na necropsia do feto, foi observada palidez de subcutâ
Arq. Bras. Med. Vet. Zootec.. Publicado em: 06/06/2019
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12. Revisiting the complete blood count and clinical findings at diagnosis of childhood acute lymphoblastic leukemia: 10-year experience at a single center
Abstract Background Heterogeneity regarding clinical and laboratory findings at diagnosis of acute lymphoblastic leukemia exists. The frequency of complete blood count abnormalities and its combinations, symptoms and physical findings were investigated in Hispanic children from an open population at the diagnosis of acute lymphoblastic leukemia. Methods Th
Hematol., Transfus. Cell Ther.. Publicado em: 15/04/2019