Infective Endocarditis in Childhood: a Single-Center Experience of 18 Years
AUTOR(ES)
Yakut, Kahraman; Ecevit, Zafer; Tokel, Niyazi Kursad; Varan, Birgul; Ozkan, Murat
FONTE
Braz. J. Cardiovasc. Surg.
DATA DE PUBLICAÇÃO
2021-04
RESUMO
Abstract Introduction: We aimed to present the risk factors, clinical and laboratory findings, treatment management, and risk factors for morbidity and mortality of infective endocarditis (IE) as well as to relate experiences at our center. Method: We retrospectively analyzed data of 47 episodes in 45 patients diagnosed with definite/possible IE according to the modified Duke criteria between May 2000 and March 2018. Results: The mean age of all patients at the time of diagnosis was 7.6±4.7 years (range: 2.4 months to 16 years). The most common symptoms and findings were fever (89.3%), leukocytosis (80.8%), splenomegaly (70.2%), and a new heart murmur or changing of pre-existing murmur (68%). Streptococcus viridans (19.1%), Staphylococcus aureus (14.8%), and coagulase-negative Staphylococci (10.6%) were the most commonly isolated agents. IE-related complications developed in 27.6% of the patients and the mortality rate was 14.8%. Conclusion: We found that congenital heart disease remains a significant risk factor for IE. The highest risk groups included operated patients who had conduits in the pulmonary position and unoperated patients with a large ventricular septal defect. Surgical intervention was required in most of the patients. Mortality rate was high, especially in patients infected with S. aureus, although the time between the onset of the first symptom and diagnosis was short. Patients with fever and a high risk of IE should be carefully examined for IE, and evaluation in favor of IE until proven otherwise will be more accurate. In high-risk patients with prolonged fever, IE should be considered in the differential diagnosis.
Documentos Relacionados
- Early Mortality Predictors in İnfective Endocarditis Patients: A Single-Center Surgical Experience
- Experience of treatment of prosthetic valve endocarditis: a retrospective single-center cross-sectional study
- Operative treatment of tertiary hyperparathyroidism: a single-center experience.
- Lead Removal Without Extraction Tools: A Single-Center Experience
- Clinical recommendations for postoperative care after heart transplantation in children: 21 years of a single-center experience