Snps
Mostrando 25-36 de 717 artigos, teses e dissertações.
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25. Genetic drift in mammals
Abstract: Genetic drift is the fortuitous occurrence of genetic events that when they become fixed modify the genome of populations. They can take the form of mutations of single nucleotides (SNPs), the insertion or deletion of short sequences (Indels) or the repetitions of short sequences (CNV i.e. copy number variants) or long insertions or deletion (struc
An. Acad. Bras. Ciênc.. Publicado em: 26/08/2019
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26. Population genomics and gene introgression in goat herds naturally adapted to Brazil
RESUMO Objetivou-se aplicar Chip SNP caprinos 50 K da Illumina para analisar a estrutura genômica populacional em dois rebanhos de caprinos Marota, um particular e outro de conservação oficial, localizados no Piauí, e na investigação de indícios de erosão genética provocada pela raça Anglonubiana nesses rebanhos. Para isso, 86 animais Marota e 10 A
Rev. Ciênc. Agron.. Publicado em: 04/07/2019
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27. Association of S100B polymorphisms and serum S100B with risk of systemic lupus erythematous in a Chinese population
Abstract The aim of this study was to investigate whether the S100B polymorphisms are associated with systemic lupus erythematous (SLE) in a Chinese population. A total of 313 SLE patients and 396 control subjects were enrolled in the present study. The genotypes of three SNPs (rs9722, rs881827 and rs1051169) in S100B gene were detected by single base extens
Genet. Mol. Biol.. Publicado em: 01/07/2019
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28. Identification of duplicates in cassava germplasm banks based on single-nucleotide polymorphisms (SNPs)
ABSTRACT: Genetic redundancy in cassava (Manihot esculenta Crantz) presents a challenge to efficient management of genetic resources. This study aimed to identify and define the genetic structure of duplicates in cassava germplasm from various Embrapa research units, using single-nucleotide polymorphism (SNP) markers. We evaluated 2,371 accessions with 20,71
Sci. agric. (Piracicaba, Braz.). Publicado em: 2019-07
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29. Association mapping in common bean revealed regions associated with Anthracnose and Angular Leaf Spot resistance
ABSTRACT: Despite important biotic stresses to common bean, Anthracnose (ANT) and Angular Leaf Spot (ALS) can cause losses of up to 80 % and occur in more than 60 countries around the world. Genetic resistance is the most sustainable strategy to manage these diseases. Thus, we aimed to (1) identify new SNP markers associated with ALS and ANT resistance loci
Sci. agric. (Piracicaba, Braz.). Publicado em: 2019-07
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30. VDR polymorphisms influence immunological response in HIV-1+ individuals undergoing antiretroviral therapy
Abstract Vitamin D exerts an immuno-modulatory activity on several immune system cells through the vitamin D receptor (VDR). Herein, we verified that age and a therapeutic regimen containing protease inhibitors are associated with failures in antiretroviral therapies (ARVs). In addition, we assessed whether a VDR SNP (rs11568820: C allele and CC genotype) an
Genet. Mol. Biol.. Publicado em: 27/06/2019
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31. Combined index of genomic prediction methods applied to productivity
RESUMO: A cultura do arroz tem grande importância nacional e mundial por ser um dos cereais mais produzidos e consumidos no mundo, caracterizando-se como o principal alimento de mais da metade da população mundial. Em função de sua importância alimentar, desenvolver métodos eficientes que visam a predição e a seleção de indivíduos geneticamente
Cienc. Rural. Publicado em: 19/06/2019
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32. SNPs rs471462296, rs456245081 and rs438495570 in the 5’UTR region of DGAT1 gene in Nelore
RESUMO O objetivo desta pesquisa foi avaliar os SNPs rs471462296, rs456245081 e rs438495570 do gene DGAT1 em bovinos Nelore. Foram analisados 109 bovinos. A extração do DNA genômico foi realizada do sangue dos animais, usando-se o kit Ilustra Blood Genomic Prep Mini Spin® (GE Healthcare, UK). A concentração e o grau de pureza do DNA foram determinados
Arq. Bras. Med. Vet. Zootec.. Publicado em: 06/06/2019
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33. Association between MBL2 haplotypes and dengue severity in children from Rio de Janeiro, Brazil
BACKGROUND Dengue is an arthropod-borne viral disease with a majority of asymptomatic individuals and clinical manifestations varying from mild fever to severe and potentially lethal forms. An increasing number of genetic studies have outlined the association between host genetic variations and dengue severity. Genes associated to viral recognition and ent
Mem. Inst. Oswaldo Cruz. Publicado em: 23/05/2019
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34. The ERBB2 gene polymorphisms rs2643194, rs2934971, and rs1058808 are associated with increased risk of gastric cancer
Gastric cancer (GC) is the third most lethal type of cancer worldwide. Single nucleotide polymorphisms (SNPs) in regulatory sites or coding regions can modify the expression of genes involved in gastric carcinogenesis, as ERBB2, which encodes for the tyrosine-kinase receptor HER-2. The aim of this work was to analyze the association of the polymorphisms: rs2
Braz J Med Biol Res. Publicado em: 16/05/2019
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35. Validation of a customized subset of SNPs for sheep breed assignment in Brazil
Resumo: O objetivo deste trabalho foi avaliar a utilidade de um subconjunto de 18 polimorfismos de nucleotídeo único (SNPs) para a certificação das raças de ovinos Crioula Brasileira, Morada Nova (MN) e Santa Inês (SI). Dados de 588 animais foram analisados com o programa Structure. Em 82% dos casos, observou-se designação racial correta com confian�
Pesq. agropec. bras.. Publicado em: 06/05/2019
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36. Polymorphisms in the CIITA −168A/G (rs3087456) and CIITA +1614G/C (rs4774) may influence severity in multiple sclerosis patients
RESUMO Atualmente não se sabe como os fatores genéticos podem influenciar o curso clínico da esclerose múltipla (EM). Objetivo: Examinamos o impacto dos polimorfismos CIITA −168A/G (rs3087456) e CIITA +1614G/C (rs4774) no risco de progressão da incapacidade, gravidade e resposta aos tratamentos imunomoduladores de primeira linha. Métodos: O DNA gen
Arq. Neuro-Psiquiatr.. Publicado em: 2019-03