Skeletal Muscle Growth
Mostrando 13-24 de 249 artigos, teses e dissertações.
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13. Gene expression promoted by the SV40 DNA targeting sequence and the hypoxia-responsive element under normoxia and hypoxia
The main objective of the present study was to find suitable DNA-targeting sequences (DTS) for the construction of plasmid vectors to be used to treat ischemic diseases. The well-known Simian virus 40 nuclear DTS (SV40-DTS) and hypoxia-responsive element (HRE) sequences were used to construct plasmid vectors to express the human vascular endothelial growth f
Brazilian Journal of Medical and Biological Research. Publicado em: 2010-08
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14. Indicadores precoces de disfunção temporomandibular e identificação de sinais e sintomas em crianças e adolescentes / Early indicators of the temporomandibular dysfunction. Identification of the signs and symptoms in children and adolescents
The objective of this work is to identify and discuss signs and symptoms of temporomandibular disorders present in children and adolescents during the intensive phase of growth and craniofacial development. Adult patients were selected for this work, who did not receive the necessary therapeutic attention and care that certainly defined their present, very d
Publicado em: 2010
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15. Bases moleculares dos efeitos da suplementação crônica com arginina sobre a sensibilidade à insulina: repercussões sobre os tecidos muscular esquelético, adiposo, hepático e sobre a secreção de insulina. / Molecular basis of the chronic effect of arginine supplementation on insulin sensitivity: repercussion in skeletal muscles, adipose tissue, liver and on insulin secretion.
Arginine (Arg) regulates the secretion of GH and insulin, and it is the main biological precursor of NO. We have previously shown that animals chronically-treated with Arg (35 mg/day) developed insulin resistance (IR), and this study investigated its molecular basis. The RI relies on the reduction of the activity and/or expression of IRS 1/2 and Akt, and of
Publicado em: 2010
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16. The inhibitory role of sympathetic nervous system in the Ca2+-dependent proteolysis of skeletal muscle
Mammalian cells contain several proteolytic systems to carry out the degradative processes and complex regulatory mechanisms to prevent excessive protein breakdown. Among these systems, the Ca2+-activated proteolytic system involves the cysteine proteases denoted calpains, and their inhibitor, calpastatin. Despite the rapid progress in molecular research on
Brazilian Journal of Medical and Biological Research. Publicado em: 2009-01
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17. Efeitos do treinamento resistido associado com decanoato de nandrolona sobre a expressão gênica de moduladores de vias de hipertrofia e atrofia do músculo esquelético
Androgenic-anabolic steroids (AAS) are spread among athletes and no athletes in order to improve performance or physical appearance. AAS targets the satellite cells in skeletal muscles, which are the major precursors of the skeletal muscle, and are essential for muscle growth and repair. When activated, in the presence of several factors, including myogenic
Publicado em: 2009
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18. Identificação de microRNAs na musculatura esquelética de Gallus gallus / Identification of microRNAs from Gallus gallus skeletal muscle
MicroRNAs (miRNAs) represent a class of small and noncoding RNAs, about 20-nucleotides long that negatively regulate gene expression posttranscriptionally. The regulatory action of these molecules is essential for the proper functioning of various biological processes, including the development and maintenance of skeletal muscles. To identify miRNAs that mig
Publicado em: 2009
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19. Identificação e caracterização funcional dos elementos cis-regulatorios da miostatina / Identification and functional characterization of the cis-regulatory elements of myostatin
The Myostatin protein (also known as GDF8) is a member of the transforming growth factor-β (TGF-β) superfamily and is expressed almost exclusively in skeletal muscle, both in the embryo and in the adult, where the protein circulates in the blood flow. It was initially identified in 1997 by MCPHERRON et al., and since then many studies have been dem
Publicado em: 2009
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20. Efeito da administração de beta hidroxi beta metilbutirato na expressão gênica da miostatina e IGF-I em músculo esquelético e do hormônio do crescimento (GH) em ratos. / Effect of the beta hidroxy beta methylbutyrate (HMb) administration on the expression of myostatin and IGF-I mRNAs in skeletal muscle, and of pituitary GH mRNA in rats.
HMb, metabólito da leucina, utilizado para aumentar a síntese protéica. Investigamos o efeito do HMb sobre o eixo somatotrófico, bem como o mRNA de IGF-I e miostatina muscular. Ratos tratados com HMb (320 mg/Kg de peso corporal /mL de salina-0,9%), ou salina (controle), gavagem, 4 semanas, decapitados, sangue para avaliação sérica: insulina (RIE), gli
Publicado em: 2009
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21. Time course of training-induced microcirculatory changes and of vegf expression in skeletal muscles of spontaneously hypertensive female rats
Exercise-induced vessel changes modulate arterial pressure (AP) in male spontaneously hypertensive rats (SHR). Vascular endothelial growth factor (VEGF) is important for angiogenesis of skeletal muscle. The present study evaluated the time course of VEGF and angiogenesis after short- and long-term exercise training of female SHR and Wistar Kyoto (WKY) rats,
Brazilian Journal of Medical and Biological Research. Publicado em: 2008-05
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22. Transferência gênica in vivo por meio de eletroporação em músculo sóleo de ratos wistar. / In vivo gene transfer by electroporation in soleus muscle from wistar rats.
The use of electrical pulses for gene transfer has been successfully used to reach significant levels of gene expression in vitro and in vivo. Therefore electroporation can be considered an important device to get further insight on biological mechanisms and also to treatment. The aim of the present work is to achieve a high level of gene transfer throughout
Publicado em: 2008
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23. Efeito do decanoato de nandrolona associado ao exercício de carga na expressão do fator de crescimento de endotélio vascular (VEGF) no músculo sóleo de ratos
Muitos estudos vêm mostrando os efeitos nocivos para o organismo do abuso de esteróides anabólicos androgênicos (EAA) por atletas e freqüentadores de academia. Entretanto há poucas pesquisas relatando os efeitos prejudiciais dessas substâncias no músculo esquelético. O objetivo desse trabalho foi analisar a expressão do fator de crescimento de endo
Publicado em: 2008
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24. Expressão dos fatores de regulação miogenica e de cadeia pesada da miosina no musculo estriado esquelitico da tilapia do Nilo (Oreochromis niloticus) durante o crecimento / Miogenic regulatory factors and myosin heavy chain expression in the striated skeletal muscle of the Nile tilapia (Oreochromis niloticus) during growth
Nos peixes, o conhecimento dos fatores que controlam o crescimento muscular e a análise das proteínas miofibrilares, é importante para entender a dinâmica do crescimento, a plasticidade e as adaptações musculares, principalmente, em espécies com grande valor comercial como a tilápia do Nilo (Oreochromis niloticus). No presente estudo, utilizou-se a t
Publicado em: 2008