Secretome
Mostrando 1-12 de 18 artigos, teses e dissertações.
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1. An in silico pipeline to filter the Toxoplasma gondii proteome for proteins that could traffic to the host cell nucleus and influence host cell epigenetic regulation
Toxoplasma gondii uses epigenetic mechanisms to regulate both endogenous and host cell gene expression. To identify genes with putative epigenetic functions, we developed an in silico pipeline to interrogate the T. gondii proteome of 8313 proteins. Step 1 employs PredictNLS and NucPred to identify genes predicted to target eukaryotic nuclei. Step 2 uses GOLi
Mem. Inst. Oswaldo Cruz. Publicado em: 28/05/2018
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2. DESAFIOS RELACIONADOS À PRODUÇÃO E APLICAÇÃO DAS ENZIMAS CELULOLÍTICAS NA HIDRÓLISE DA BIOMASSA LIGNOCELULÓSICA
The second generation (2G) ethanol obtained from lignocellulosic biomass has been considered as a potential alternative source of energy for the transportation sector. However, the technologies to convert lignocellulose into fermentable sugars still face several challenges. One of the major challenges of this process is related to the cost of the cellulolyti
Quím. Nova. Publicado em: 2017-09
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3. Análise do secretoma do fungo Trichoderma harzianum crescido em presença de glicose ou parede celular de Fusarium solani / Analysis of the secretome of Trichoderma harzianum grown in the presence of glucose or cell walls of Fusarium solani
Trichoderma harzianum é um fungo saprofítico, conhecido devido ao seu grande potencial como agente de controle biológico de diferentes fitopatógenos. Sua ação é baseada em diferentes mecanismos como a produção de antibióticos voláteis e não-voláteis, competição por espaço e nutrientes, produção de enzimas hidrolíticas e o micoparasitismo.
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 31/03/2010
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4. Analysis of the secretome of Trichoderma harzianum grown in the presence of glucose or cell walls of Fusarium solani / Análise do secretoma do fungo Trichoderma harzianum crescido em presença de glicose ou parede celular de Fusarium solani
Trichoderma harzianum é um fungo saprofítico, conhecido devido ao seu grande potencial como agente de controle biológico de diferentes fitopatógenos. Sua ação é baseada em diferentes mecanismos como a produção de antibióticos voláteis e não-voláteis, competição por espaço e nutrientes, produção de enzimas hidrolíticas e o micoparasitismo.
Publicado em: 2010
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5. The Mouse Secretome: Functional Classification of the Proteins Secreted Into the Extracellular Environment
We have developed a computational strategy to identify the set of soluble proteins secreted into the extracellular environment of a cell. Within the protein sequences predominantly derived from the RIKEN representative transcript and protein set, we identified 2033 unique soluble proteins that are potentially secreted from the cell. These proteins contai
Cold Spring Harbor Laboratory Press.
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6. Secretome Analysis Reveals an Arabidopsis Lipase Involved in Defense against Alternaria brassicicolaW⃞
The Arabidopsis thaliana secretome was analyzed by the proteomic approach, which led to the identification of secreted proteins implicated in many aspects of cell biology. We then investigated the change in the Arabidopsis secretome in response to salicylic acid and identified several proteins involved in pathogen response. One of these, a secreted lipase wi
American Society of Plant Biologists.
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7. Signal Peptide-Dependent Protein Transport in Bacillus subtilis: a Genome-Based Survey of the Secretome
One of the most salient features of Bacillus subtilis and related bacilli is their natural capacity to secrete a variety of proteins into their environment, frequently to high concentrations. This has led to the commercial exploitation of bacilli as major “cell factories” for secreted enzymes. The recent sequencing of the genome of B. subtilis has provid
American Society for Microbiology.
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8. Inter- and Intraclonal Diversity of the Pseudomonas aeruginosa Proteome Manifests within the Secretome
The proteomes of cultured Pseudomonas aeruginosa isolates from chronically infected cystic fibrosis (CF) lungs were compared by using genetically divergent clones and isogenic morphotypes of one strain. Cellular extracts gave very similar protein patterns in two-dimensional gels, suggesting that the conserved species-specific core genome encodes proteins tha
American Society for Microbiology.
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9. Proteome Analysis of Secreted Proteins of the Gastric Pathogen Helicobacter pylori
Secreted proteins (the secretome) of the human pathogen Helicobacter pylori may mediate important pathogen-host interactions, but such proteins are technically difficult to analyze. Here, we report on a comprehensive secretome analysis that uses protein-free culture conditions to minimize autolysis, an efficient recovery method for extracellular proteins, an
American Society for Microbiology.
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10. Proteomics of Protein Secretion by Bacillus subtilis: Separating the “Secrets” of the Secretome
Secretory proteins perform a variety of important “remote-control” functions for bacterial survival in the environment. The availability of complete genome sequences has allowed us to make predictions about the composition of bacterial machinery for protein secretion as well as the extracellular complement of bacterial proteomes. Recently, the powe
American Society for Microbiology.
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11. Outside the Unusual Cell Wall of the Hyperthermophilic Archaeon Aeropyrum pernix K1
In contrast to the extensively studied eukaryal and bacterial protein secretion systems, comparatively less is known about how and which proteins cross the archaeal cell membrane. To identify secreted proteins of the hyperthermophilic archaeon Aeropyrum pernix K1 we used a proteomics approach to analyze the extracellular and cell surface protein fractions. T
The American Society for Biochemistry and Molecular Biology.
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12. Discovering New Bioactive Neuropeptides in the Striatum Secretome Using in Vivo Microdialysis and Versatile Proteomics S⃞
The striatum, a major component of the brain basal nuclei, is central for planning and executing voluntary movements and undergoes lesions in neurodegenerative disorders such as Huntington disease. To perform highly integrated tasks, the striatum relies on a complex network of communication within and between brain regions with a key role devoted to secreted
American Society for Biochemistry and Molecular Biology.