Second Malignancy
Mostrando 13-24 de 59 artigos, teses e dissertações.
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13. Análise de expressão de micro RNA em carcinoma urotelial de bexiga / Analysis of micro RNA expression in bladder urothelial carcinoma
Introduction: Bladder cancer (BC) is the second most common malignancy of the urinary tract, with 386,000 cases estimated and 150,000 deaths in 2011. Urothelial carcinomas (UC) represent 95% of BC cases, and knowledge of the molecular pathways associated with BC carcinogenesis is crucial to identify new diagnostic and prognostic biomarkers, and development o
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 27/07/2012
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14. Urethral skip metastasis from cancer penis or a second malignancy?a dilemma!
International braz j urol. Publicado em: 2011-10
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15. Prevenção do Câncer do Colo do Útero na Estratégia Saúde da Família: contribuições para a capacitação do Agente Comunitário de Saúde / Prevention of Uterine Cervical Cancer in The Family Health Program: contributions to the empowerment of the Community Health Agent.
Introduction: Uterine cervical cancer (UCC) is the second most common malignancy among women in Brazil, the main strategy for early detection of premalignant lesions is the cytopathology. Despite the existence of the screening program there was no reduction in the incidence and mortality rate of UCC in Brazil. The Family Health Strategy has the potential to
Publicado em: 2011
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16. Cytogenetic characterization and evaluation of c-MYC gene amplification in PG100, a new Brazilian gastric cancer cell line
Gastric cancer is the fourth most frequent type of cancer and the second cause of cancer mortality worldwide. The genetic alterations described so far for gastric carcinomas include amplifications and mutations of the c-ERBB2, KRAS, MET, TP53, and c-MYC genes. Chromosomal instability described for gastric cancer includes gains and losses of whole chromosomes
Brazilian Journal of Medical and Biological Research. Publicado em: 2010-08
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17. Estudo comparativo da expressão imuno-histoquímica do ki-67 em carcinoma epidermóide de língua em pacientes jovens e idosos
The squamous cell carcinoma (SCC) is the most common malignant neoplasm of epithelial origin in oral cavity and present high capacity to invade adjacent structures. Traditionally, SCC has a predominance of 50 years male patients with long-time use of tobacco and alcohol, and the tongue is the most affected anatomic site. At present, there is an increasing in
Publicado em: 2010
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18. Irinotecan and oxaliplain : an overview of the novel chemotherapeutic options for the treatment of advanced colorectal cancer
Colorectal cancer is one of the most frequent malignancies in humans and an important cause of cancer death. Metastatic colorectal cancer remains incurable with available systemic therapeutic options. The most active cytotoxic drug against this malignancy, the antimetabolite 5-fluorouracil, was developed more than forty years ago, and as a single agent produ
Publicado em: 2010
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19. Estudo morfológico e por citogenética da medula óssea de portadores de síndrome mielodisplásica secundária no Serviço de Hematologia do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo / Morphological and cytogenetic bone marrow studies in patients with secondary myelodysplastic syndrome diagnosed at Department of Hematology of Clinical Hospital of São Paulo Medical School
As Síndromes mielodisplásicas (SMD) são doenças clonais da célula progenitora hematopoética, cursando com citopenias, medula óssea displástica e tendência à evolução para leucemia. As SMD secundárias estão associadas a fatores de risco como doenças congênitas (Anemia de Fanconi), doenças hematológicas adquiridas (aplasia medular, HPN), expo
Publicado em: 2010
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20. HistoquÃmica com lectinas de sementes de Cratylia mollis analisando tecidos prostÃticos humanos
Prostate cancer is a malignant tumour of major incidence in elderly men in the developed countries and the second major cause of death for cancer. Lectins are proteins or glycoproteins, which recognize specifically and reversibly free or conjugated carbohydrates. They have been used in histochemistry to evaluate changes in the composition and expression of c
Publicado em: 2009
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21. Flavins promote changes in the extracellular matrix, signal transduction, antioxidant enzymes and metalloproteinases during osteoblast differentiation / Flavinas promovem mudanças na matriz extracelular, vias de transdução de sinal, enzimas antioxidantes e metaloproteinases durante a diferenciação de osteoblastos
Riboflavin (Rb-Vitamin B2) is the precursor of essential flavocoenzymes, flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD). These coenzymes participate in numerous enzymatic processes dependent on electron transfer reactions that occur in energyproducing, biosynthetic, and detoxifying and electron-scavenging pathways. Increase dietary ribofla
Publicado em: 2009
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22. Methylation status of ANAPC1, CDKN2A and TP53 promoter genes in individuals with gastric cancer
Gastric cancer is the forth most frequent malignancy and the second most common cause of cancer death worldwide. DNA methylation is the most studied epigenetic alteration, occurring through a methyl radical addition to the cytosine base adjacent to guanine. Many tumor genes are inactivated by DNA methylation in gastric cancer. We evaluated the DNA methylatio
Brazilian Journal of Medical and Biological Research. Publicado em: 2008-06
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23. Utilização de equações diferenciais parciais para eliminação de ruídos e detecção de bordas
The edge detection of digital images is a research field that has attracted great interest from the scientific community. Their applications go from the automatic inspection and quality control of industrial piece to the diagnosis of malignancy of cancerous tumors. However, many existing edge detectors have problems related to false edge detection. In this c
Publicado em: 2008
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24. VariaÃÃes transcricionais dos genes AR, SRD5A2, KLK2, PCA3, KLK3 e PSMA e implicaÃÃes no diagnÃstico molecular do cÃncer de prÃstata
CHAPTER I - Prostate cancer is a common disease in the world and in some countries it is one of the main causes of male population mortality. Some molecular markers have been associated with prostate carcinogenesis. To observe changes in transcript levels of the AR, SRD5A2, KLK2, PSMA and PCA3 genes, the mRNA was analyzed in tissues with prostatic adenocarci
Publicado em: 2007