Satellite Cells Of Skeletal Muscle
Mostrando 1-12 de 37 artigos, teses e dissertações.
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1. Células satélites e fusos neuromusculares em músculos estriados de ratos desnervados por longo período / Satellite cells and neuromuscular spindles in skeletal muscles in long term denervated rats
O músculo estriado esquelético apresenta em sua constituição células satélites (CS) que se encontram em estado quiescente localizadas entre o sarcolema e a lâmina basal das fibras musculares. As CS podem ser ativadas, diferenciando em mioblastos, contribuindo para regeneração e/ou crescimento do tecido muscular. Os Fusos neuromusculares são mecanor
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 22/06/2012
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2. Influência das HSPs (heat shock proteins) e do mTORC-1 (mammalian target of rapamycin complex 1) na regeneração de músculos esqueléticos. / Influence of HSPs (heat shock proteins) and mTORC1 (mammalian target of rapamycin complex 1) in skeletal muscle regeneration.
The goal of this work was to contribute to a better understanding about the intracellular mechanisms involved in skeletal muscle regeneration by studying the influence of heat shock proteins (HSPs) and mTORC1 (mammalian target of rapamycin complex 1) in the muscle regeneration process. The treatment with radicicol (a HSP inductor) in injured muscles induced
Publicado em: 2009
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3. Efeitos do treinamento resistido associado com decanoato de nandrolona sobre a expressão gênica de moduladores de vias de hipertrofia e atrofia do músculo esquelético
Androgenic-anabolic steroids (AAS) are spread among athletes and no athletes in order to improve performance or physical appearance. AAS targets the satellite cells in skeletal muscles, which are the major precursors of the skeletal muscle, and are essential for muscle growth and repair. When activated, in the presence of several factors, including myogenic
Publicado em: 2009
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4. Ação da laserterapia de baixa intensidade (830nm) na regeneração muscular de ratos idosos
The elderly still go through physical changes, especially musculoskeletal disorders such as sarcopenia, changes in central and peripheral nervous system, blood hypoperfusion, regenerative changes contributing to atrophy and muscle weakness, undermining the activities of daily living (AVL). The regenerative process happens about the determination, proliferati
Publicado em: 2009
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5. Avaliação do padrão de degeneração e regeneração muscular em diferentes modelos murinos para distrofias musculares progressivas / Study of degeneration and regeneration pathways, in mice models for muscular dystrophies
The muscular dystrophies are a heterogeneous group of genetic diseases characterized by progressive and irreversible degeneration of skeletal muscles. Muscle weakness is the consequence of an imbalance between successive cycles of degeneration and regeneration, with further replacement of the degraded muscle fibers by adipose and connective tissues. Several
Publicado em: 2009
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6. Involvement of eukaryotic translation initiation factor 5a (eif5a) in skeletal muscle stem cell differentiation. / Envolvimento do fator de início de tradução de eucariotos 5A (elF5A) na diferenciação de células-tronco da musculatura esquelética
A proteína eIF5A apresenta um resíduo exclusivo de aminoácido chamado hipusina formado por modificação pós-traducional envolvendo espermidina como substrato. Neste estudo, observamos que a expressão de eIF5A é intensificada ao longo da diferenciação de células-tronco progenitoras de fibras musculares (células satélites) e que a inibição da hip
Publicado em: 2007
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7. Ectopic development of skeletal muscle induced by subcutaneous transplant of rat satellite cells
The present study analyzes the ectopic development of the rat skeletal muscle originated from transplanted satellite cells. Satellite cells (10(6) cells) obtained from hindlimb muscles of newborn female 2BAW Wistar rats were injected subcutaneously into the dorsal area of adult male rats. After 3, 7, and 14 days, the transplanted tissues (N = 4-5) were proce
Brazilian Journal of Medical and Biological Research. Publicado em: 2005-03
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8. Dual-channel laser scanning microscopy for the identification and quantification of proliferating skeletal muscle satellite cells following synergist ablation.
Proliferating skeletal muscle satellite cells are the source of additional myonuclei which allow skeletal muscle to grow and regenerate. Previously, proliferating satellite cells were identified in situ by techniques which were limited either by tissue processing time or inability to observe complete muscle sections, or by errors made in separating these cel
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9. Skeletal muscle stem cells
Satellite cells are myogenic stem cells responsible for the post-natal growth, repair and maintenance of skeletal muscle. This review focuses on the basic biology of the satellite cell with emphasis on its role in muscle repair and parallels between embryonic myogenesis and muscle regeneration. Recent advances have altered the long-standing view of the satel
BioMed Central.
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10. A role for FGF-6 in skeletal muscle regeneration
Fibroblast growth factor-6 (FGF-6) belongs to a family of cytokines that control cell proliferation, cell differentiation, and morphogenetic events. Individual FGFs are either expressed widely or in a restricted pattern during embryonic, fetal, and adult life. FGF-6 exhibits a restricted expression profile predominantly in the myogenic lineage. Important fun
Cold Spring Harbor Laboratory Press.
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11. Essential and separable roles for Syndecan-3 and Syndecan-4 in skeletal muscle development and regeneration
Syndecan-3 and syndecan-4 function as coreceptors for tyrosine kinases and in cell adhesion. Syndecan-3-/- mice exhibit a novel form of muscular dystrophy characterized by impaired locomotion, fibrosis, and hyperplasia of myonuclei and satellite cells. Explanted syndecan-3-/- satellite cells mislocalize MyoD, differentiate aberrantly, and exhibit a general i
Cold Spring Harbor Laboratory Press.
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12. A role for the ETS domain transcription factor PEA3 in myogenic differentiation.
Activation of adult myoblasts called satellite cells during muscle degeneration is an important aspect of muscle regeneration. Satellite cells are believed to be the only myogenic stem cells in adult skeletal muscle and the source of regenerating muscle fibers. Upon activation, satellite cells proliferate, migrate to the site of degeneration, and become comp