Regulatory Regions
Mostrando 1-12 de 2154 artigos, teses e dissertações.
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1. Association of FAAH p.Pro129Thr and COMT p.Ala72Ser with schizophrenia and comorbid substance use through next-generation sequencing: an exploratory analysis
Objective: Individuals with schizophrenia and substance use disorders have a poor prognosis and increased psychiatric symptoms. The present study aimed to explore the association of 106 genes in individuals with schizophrenia and comorbid substance use through a next-generation sequencing (NGS) analysis and different in silico algorithms. Methods: We includ
Brazilian Journal of Psychiatry. Publicado em: 2022
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2. Social Accountability of Medical Schools and Social Representations of Medical Students in the Context of the More Doctors Program
RESUMO Diversos debates, no contexto nacional e internacional, têm sugerido a necessidade de mudanças na formação médica, de modo que ela esteja em consonância com a organização dos sistemas de saúde. Nessa perspectiva, propõe-se que as escolas sejam orientadas pela responsabilidade social, que consiste em ordenar o ensino, a pesquisa e as atividad
Rev. bras. educ. med.. Publicado em: 13/01/2020
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3. Sobrecarga térmica em áreas rurais: a influência da intensidade do trabalho
Resumo Introdução: a legislação brasileira determina que se monitore o Índice de Bulbo Úmido Termômetro de Globo (IBUTG) nos ambientes de trabalho em que o calor possa representar risco à saúde dos trabalhadores. Porém, esse monitoramento e a adoção de medidas preventivas não são comumente observados. Objetivo: identificar e mapear a influ�
Rev. bras. saúde ocup.. Publicado em: 11/11/2019
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4. V Brazilian consensus guidelines for detection of anti-cell autoantibodies on hep-2 cells
Abstract Background: The V Brazilian Consensus for determination of autoantibodies against cellular constituents on HEp-2 cells, held in Brasilia (DF, Brazil) on August 27, 2016, discussed the harmonization between the Brazilian Consensus on ANA (BCA) guidelines and the International Consensus on ANA Patterns (ICAP) recommendations (www.anapatterns.org). In
Adv. rheumatol.. Publicado em: 29/07/2019
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5. Comparative genome analysis of the SPL gene family reveals novel evolutionary features in maize
Abstract SPLs are plant-specific transcription factors that play important regulatory roles in plant growth and development. Systematic analysis of the SPL family has been performed in numerous plants, such as Arabidopsis, rice, and Populus. However, no comparative analysis has been performed across different species to examine evolutionary features. In this
Genet. Mol. Biol.. Publicado em: 01/07/2019
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6. The ERBB2 gene polymorphisms rs2643194, rs2934971, and rs1058808 are associated with increased risk of gastric cancer
Gastric cancer (GC) is the third most lethal type of cancer worldwide. Single nucleotide polymorphisms (SNPs) in regulatory sites or coding regions can modify the expression of genes involved in gastric carcinogenesis, as ERBB2, which encodes for the tyrosine-kinase receptor HER-2. The aim of this work was to analyze the association of the polymorphisms: rs2
Braz J Med Biol Res. Publicado em: 16/05/2019
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7. Detection of differentially methylated regions of irradiated fig tree selections
ABSTRACT Fig tree (Ficus carica L.) breeding programs using conventional methods, such as directed crosses, to obtain new cultivars, are unworkable in many countries, including Brazil. Consequently, genetic breeding through mutagenesis has emerged as an important line of research that can improve this crop, and be a significant source of information about th
Sci. agric. (Piracicaba, Braz.). Publicado em: 2017-08
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8. Rice genotypes for drought tolerance: morphological and transcriptional evaluation of auxin-related genes
ABSTRACT Drought stress affects crop quality and productivity. The challenge of increasing food availability for a growing worldwide demand relies on the development of tolerant cultivars that will need to be adapted to arid and semi-arid areas. In order to help the understanding of rice response to stress, the phenotypic response of 6 Brazilian rice cultiva
Bragantia. Publicado em: 29/09/2016
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9. Genetic diversity and prevalence of CCR2-CCR5 gene polymorphisms in the Omani population
Polymorphisms in the regulatory region of the CCR5 gene affect protein expression and modulate the progress of HIV-1 disease. Because of this prominent role, variations in this gene have been under differential pressure and their frequencies vary among human populations. The CCR2V64I mutation is tightly linked to certain polymorphisms in the CCR5 gene. The c
Genet. Mol. Biol.. Publicado em: 2014
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10. Effect of treatment with cyclophosphamide in low doses upon the onset of delayed type hypersensitivity in mice chronically infected with Trypanosoma cruzi: involvement of heart interstitial dendritic cells
Acute infection with Trypanosoma cruzi results in intense myocarditis, which progresses to a chronic, asymptomatic indeterminate form. The evolution toward this chronic cardiac form occurs in approximately 30% of all cases of T. cruzi infection. Suppression of delayed type hypersensitivity (DTH) has been proposed as a potential explanation of the indetermina
Mem. Inst. Oswaldo Cruz. Publicado em: 2013-09
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11. Avaliação da expressão de receptores e ligantes Notch nas populações de linfócitos T em desenvolvimento, linfócitos T reguladores naturais e células dendríticas no timo humano / Evaluation of the expression of Notch receptors and ligands in developing lymphocytes, natural regulatory T cells and dendritic cells in human thymus
The thymus is a primary lymphoid organ responsible of maturing T lymphocytes, where specialized structures and cells are observed. The intrathymic signaling during lymphocytes maturation is unclear. Among them, Notch signaling pathway, which comprises in receptors (Notch1-4) and ligands (DLL1, 2 and 3, Jaaged1 and 2), may regulate this process. In this work
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 10/09/2012
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12. Indução do promotor GmNAC6 por elicitores de estresses e mapeamento de regiões reguladoras / Induction of the promoter GmNAC6 by elicitors of stress and mapping of regulatory regions
NAC domain-containing proteins are unique to plants and comprise a large gene family of transcriptional factors implicated in diverse aspects of plant development and stress responses. The GmNAC6 was recently identified as a downstream component of the ER (endoplasmic reticulum) stress- and osmotic stress-induced NRP (N-rich proteins)-mediated cell death sig
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 23/02/2012