Receptors Chemokine
Mostrando 13-24 de 316 artigos, teses e dissertações.
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13. HIV-1 tropism and CD4 T lymphocyte recovery in a prospective cohort of patients initiating HAART in Ribeirão Preto, Brazil
While human immunodeficiency virus (HIV)-1 chemokine co-receptors 5 tropism and the GWGR motif in the envelope third variable region (V3 loop) have been associated with a slower disease progression, their influence on antiretroviral response remains unclear. The impact of baseline V3 characteristics on treatment response was evaluated in a randomised, double
Memórias do Instituto Oswaldo Cruz. Publicado em: 2012-02
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14. O papel das quimiocinas CCL3, CCL2 e seus receptores na movimentação dentária ortodôntica
Orthodontic tooth movement (OTM) is achieved by the remodeling of periodontal ligament (PDL) and alveolar bone in response to mechanical loading. This process is regulated by pro-inflammatory mediators, such as cytokines and chemokines. CCL2, CCL3 and CCL5 are chemokines involved in osteoclastogenesis and are upregulated in periodontium after mechanical load
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 23/11/2011
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15. Expression of the chemokine receptor CXCR4 on lymphocytes of leprosy patients
Leprosy is caused by Mycobacterium leprae, which induces chronic granulomatous infection of the skin and peripheral nerves. The disease ranges from the tuberculoid to the lepromatous forms, depending on the cellular immune response of the host. Chemokines are thought to be involved in the immunopathogenesis of leprosy, but few studies have investigated the e
Brazilian Journal of Medical and Biological Research. Publicado em: 2011-12
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16. The effect of combined polymorphisms in chemokines and chemokine receptors on the clinical course of HIV-1 infection in a Brazilian population
Polymorphisms in genes that encode chemokines or their receptors can modulate susceptibility to human immunodeficiency virus (HIV) infection and disease progression. The objective of this study was to assess the frequency of polymorphisms CCR5-Δ32, CCR2-64I, CCR5-59029A and SDF1-3'A and their role in the course of HIV infection in a Southern Brazilian popul
Mem. Inst. Oswaldo Cruz. Publicado em: 2011-06
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17. Soluble inflammatory markers as predictors of virological response in patients with chronic hepatitis C virus infection treated with interferon-α plus ribavirin
The host immune response plays an important role in viral clearance in patients who are chronically infected with hepatitis C virus (HCV) and are treated with interferon and ribavirin. Activation of the immune system involves the release of pro and anti-inflammatory molecules that can be measured in plasma samples. The present study aimed to evaluate the ass
Memórias do Instituto Oswaldo Cruz. Publicado em: 2011-02
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18. Chagas' disease and Duffy antigen/receptor for chemokine (DARC): a mini-review
Duffy gene (FY) codifies the transmembrane glycoprotein Duffy (gp-Fy) of 35 to 43 kDa which is moderately immunogenic. This glycoprotein is polymorphic, and constitutes the antigens of the Duffy histo-blood system which were designated receptors for chemokines and denominated DARC (Duffy antigen/receptor for chemokine). This receptor has an important role in
Journal of Venomous Animals and Toxins including Tropical Diseases. Publicado em: 2011
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19. In vitro initial immune response against Leishmania amazonensis infection is characterized by an increased production of IL-10 and IL-13
The initial encounter of Leishmania with its host's immune system is important in the outcome of infection. Previous studies have shown that PBMCs from healthy volunteers (HV) exposed to Leishmania differ in IFN-γ production. We have expanded such observations evaluating the profile and kinetics of cytokines (IFN-γ, IL-12p70, IL-10, IL-13), chemokines (CCL
Brazilian Journal of Infectious Diseases. Publicado em: 2010-10
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20. Seric chemokines and chemokine receptors in eosinophils during acute human schistosomiasis mansoni
The recruitment of circulating eosinophils by chemokines and chemokine receptors plays an important role in the inflammation process in acute human schistosomiasis. Our main focus has been on the plasma chemokines (CXCL8/CCL2/CCL3/CCL24) and chemokine receptors (CCR2/CCR3/CCR5/CXCR1/CXCR2/CXCR3/CXCR4) expressed by circulating eosinophils from acute Schistoso
Memórias do Instituto Oswaldo Cruz. Publicado em: 2010-07
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21. Imunopatologia da dengue: receptores de quimiocinas CC e células iNKT
Dengue virus (DENV), a mosquito-borne flavivirus, is a serious public health problem in many tropical countries. Immune mechanisms involved in the pathogenesis of DENV infection are not fully elucidated. Recent clinical data showed an association between levels of different CC chemokines in plasma and severity of dengue. In this regard, we evaluated the role
Publicado em: 2010
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22. Frequency of CCR5delta32 in brazilian populations
A sample of 103 randomly chosen healthy individuals from Alegrete, RS, Brazil, was tested for the CCR5Δ32 allele, which is known to influence susceptibility to HIV-1 infection. The CCR5Δ32 allele was identified by PCR amplification using specific primers flanking the region of deletion, followed by electrophoresis on a 3% agarose gel. The data obtained wer
Publicado em: 2010
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23. Chronic Trypanosoma cruzi-elicited cardiomyopathy: from the discovery to the proposal of rational therapeutic interventions targeting cell adhesion molecules and chemokine receptors - how to make a dream come true
One hundred years ago, Carlos Chagas discovered a new disease, the American trypanosomiasis. Chagas and co-workers later characterised the disease's common manifestation, chronic cardiomyopathy, and suggested that parasitic persistence coupled with inflammation was the key underlying pathogenic mechanism. Better comprehension of the molecular mechanisms lead
Memórias do Instituto Oswaldo Cruz. Publicado em: 2009-07
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24. Perfil de Quimiocinas em Indivíduos Portadores de Lesão Ocular Decorrente da Infecção pelo Toxoplasma gondii
The high prevalence of toxoplasmosis at Campos dos Goytacazes city is recognized as the highest described in literature, where the prevalence of ocular disease is situated from 6 to 14% for the seropositive population. The role of chemokines and their receptors in the ocular pathology process from infectious diseases has not been well studied. In this contex
Publicado em: 2008