Pyridines
Mostrando 13-23 de 23 artigos, teses e dissertações.
-
13. Synthesis of new trihalomethylated and non-symmetrical substituted 2-(1H-pyrazolyl)-5-(1H-pyrazolylcarbonyl)pyridines
Este trabalho apresenta a síntese de uma nova série de 2-[3-alquil (aril/heteroaril)-5-trialometil-5-hidróxi-4,5-diidro-1H-pirazol-1-il]-5-[3-alquil(aril/heteroaril)-5-trialometil-5-hidróxi-4,5-diidro-1H-pirazol-1-il-1-carbonil]piridinas, obtida a partir de reações de ciclocondensação de 4-alcóxi-4-alquil(aril/heteroaril)-1,1,1-trialo-3-alquen-2-ona
Journal of the Brazilian Chemical Society. Publicado em: 2009
-
14. Syntheses, Characterization and Chemical Reactivity of Chloro and Nitrosyl Complexes of trans-Tetrakispyridines of Ruthenium / Síntese, caracterização e reatividade química de complexos de cloro e nitrosil de trans-Tetrakispiridina de rutênio
The complexes trans-[RuCl2(L)4] (L = py, isn, 4-acpy e 3-acpy), trans-[RuCl(NO)(L)4](PF6)2 (L = py, isn e 4-acpy), trans-[Ru(OH)(NO)(py)4](PF6)2, trans-[RuCl(NO)(py)4]Cl23H2O, trans-[Ru(OH)(NO)(py)4]Cl2, cis-[RuCl2(DMSO)4], trans-[Ru(NO2)2(py)4], trans-[RuCl(NO2)(py)4], trans-[RuCl(acn)(py)4](PF6) and the reduced complex trans-[RuCl(NO)(py)4]I were synthesiz
Publicado em: 2009
-
15. SYNTHESIS OF 2-(1H-PYRAZOL-1-IL)-5-(1H-PYRAZOL-1-IL-1-CARBONYL) PYRIDINES / SÍNTESE DE 2-(1H-PIRAZOL-1-IL)-5-(1H-PIRAZOL- 1-IL-1-CARBONIL) PIRIDINAS
Esta dissertação apresenta a síntese de uma nova série de 2-[3-alquil (aril/heteroaril)-5-trialometil-5-hidroxi-4,5-diidro-1H-pirazol-1-il]-5-[3- alquil(aril/heteroaril)-5-trialometil-5-hidroxi-4,5-diidro-1H-pirazol-1-il-1- carbonil]piridinas, obtida a partir de reações de ciclocondensação de 1,1,1-trialo-4- alquil(aril/heteroaril)-4-alcoxi-3-alquen-
Publicado em: 2008
-
16. Sobre o emprego da 4-aminopiridina, 3.4-diaminopiridina e da neostigmina como antagonista de curare : estudo comparativo
The effects ot 4-aminopyridine (1; 5 e 25 ug/ml), 3.4-diaminopyridine (1; 5 and 25 ug/ml) as well as the association of the drugs with neostigmine, were investigated using the noncurarized rat s phrenic nerve-hemidiaphragm preparations and d-tubocurarine-blocked preparations. The preparations were treated by two different procedures; indirect estimulation by
Publicado em: 1981
-
17. Effect of pyridines on phenotypic properties of Bordetella pertussis.
Several conditions of growth of Bordetella pertussis cause a reversible phenotypic alteration in properties termed modulation. Growth in medium containing nicotinic acid induces normal (X-mode) cells to change to modulated (C-mode) cells. We examined several pyridines and compounds resembling pyridines for their ability to affect modulation, using envelope p
-
18. Antimicrobial Performance of Tri- and Tetrachloro-4-(Methylsulfonyl) Pyridines as Industrial Preservatives
Tests show that trichloro- and tetrachloro-4-(methylsulfonyl) pyridines have a wide spectrum of activity against microorganisms causing deterioration in industrial systems. They are particularly active as fungistats and are more effective against gram-positive than against gram-negative bacteria. Their fungistatic activity and persistence have led to outstan
-
19. Pyridines and Pyrimidines Mediating Activity against an Efflux-Negative Strain of Candida albicans through Putative Inhibition of Lanosterol Demethylase
The first step in ergosterol biosynthesis in Saccharomyces cerevisiae consists of the condensation of two acetyl coenzyme A (acetyl-CoA) moieties by acetoacetyl-CoA thiolase, encoded by ERG10. The inhibition of the sterol pathway results in feedback activation of ERG10 transcription. A cell-based reporter assay, in which increased ERG10 transcription results
American Society for Microbiology.
-
20. In vitro antiviral activity of the 6-substituted 2-(3',4'-dichlorophenoxy)-2H-pyrano[2,3-b]pyridines MDL 20,610, MDL 20,646, and MDL 20,957.
The 6-substituted 2-(3',4'-dichlorophenoxy)-2H-pyrano[2,3-b]pyridines MDL 20,610 (6-SO2CH3), MDL 20,646 (6-Br), and MDL 20,957 (6-Cl) are potent antirhinovirus compounds with median plaque 50% inhibitory concentrations (IC1/2s) of 0.03, 0.006, and 0.006 micrograms/ml, respectively, against the 32 serotypes evaluated. The 6-halogenated analogs produced 99% re
-
21. Microbial metabolism of pyridine, quinoline, acridine, and their derivatives under aerobic and anaerobic conditions.
Our review of the metabolic pathways of pyridines and aza-arenes showed that biodegradation of heterocyclic aromatic compounds occurs under both aerobic and anaerobic conditions. Depending upon the environmental conditions, different types of bacteria, fungi, and enzymes are involved in the degradation process of these compounds. Our review indicated that di
-
22. Transformation of 3- and 4-Picoline under Sulfate-Reducing Conditions
A microbial population which transformed 3- and 4-picoline under sulfate-reducing conditions was isolated from a subsurface soil which had been previously exposed to different N-substituted aromatic compounds for several years. In the presence of sulfate, the microbial culture transformed 3- and 4-picoline (0.4 mM) within 30 days. From the amounts of ammonia
-
23. Metabolism of Pyridine Compounds by Phthalate-Degrading Bacteria
Bacteria were isolated from marine sediments that grew aerobically on m-phthalate, p-phthalate, or dipicolinate (2,6-pyridine dicarboxylate [2,6-PDCA]). Strain OP-1, which grew on o-phthalate and was previously obtained from a marine source, was also studied. Intact cells of each organism demonstrated Na+-dependent oxidation of their growth substrates. Strai