Protein Pattern
Mostrando 13-24 de 4422 artigos, teses e dissertações.
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13. BthTX-I from Bothrops jararacussu induces apoptosis in human breast cancer cell lines and decreases cancer stem cell subpopulation
ABSTRACT Background: Breast cancer is the neoplasm with both the highest incidence and mortality rate among women worldwide. Given the known snake venom cytotoxicity towards several tumor types, we evaluated the effects of BthTX-I from Bothrops jararacussu on MCF7, SKBR3, and MDAMB231 breast cancer cell lines. Methods: BthTX-I cytotoxicity was determined
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 29/07/2019
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14. A Novel Missense Mutation in SRD5A3 Causes Congenital Disorder of Glycosylation Type I (Cerebello-Ocular Syndrome)
Abstract A consanguineous Qatari family having an autosomal recessive disorder characterized by severe mental retardation, cerebellar vermis hypoplasia, retinal degeneration, optic nerve atrophy, ataxic gait, and seizures was studied for identification of the offending gene and mutation. Homozygosity mapping identified an 11.4 Mb critical interval at 4q12 to
J. inborn errors metab. screen.. Publicado em: 15/07/2019
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15. Correlation between CSF biomarkers of Alzheimer’s disease and global cognition in a psychogeriatric clinic cohort
Objective: The relationship between biomarkers of amyloid-beta aggregation (Aβ1-42) and/or neurodegeneration (Tau protein) in cerebrospinal fluid (CSF) and cognitive decline is still unclear. We aimed to ascertain whether CSF biomarkers correlate with cognitive performance in healthy and cognitively impaired subjects, starting from clinical diagnoses. Met
Braz. J. Psychiatry. Publicado em: 30/05/2019
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16. ENROFLOXACINO DE RÁPIDA AÇÃO EM ASSOCIAÇÃO A FLUIDOTERAPIA ENDOVENOSA E ORAL NO TRATAMENTO DE DIARREIA NEONATAL BOVINA
Resumo O objetivo deste trabalho foi avaliar a ação do enrofloxacino de rápida ação e sua associação com outros tratamentos como, suporte por via oral ou endovenosa em bezerras leiteiras com diarreia. Foram utilizados 56 animais, divididos em grupos: Grupo SADIAS (n=5), Grupo Antibiótico (ATB; n=15), Grupo Antibiótico + Suporte Endovenoso (ATB+SE; n
Ciênc. anim. bras.. Publicado em: 18/03/2019
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17. Retinal dystrophies and variants in PRPH2
RESUMO | Este relato apresenta três pacientes com diagnóstico de distrofias maculares com mutações no PRPH2. Periferina 2, a proteína deste gene, é importante na morfogênese e estabilização do segmento externo dos fotorreceptores. Deficiências de periferina 2 causam apoptose celular. Além disso, variantes patogênicas no PRPH2 estão relacionadas
Arq. Bras. Oftalmol.. Publicado em: 2019-03
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18. Glycoprotein nonmetastatic melanoma protein B accelerates tumorigenesis of cervical cancer in vitro by regulating the Wnt/β-catenin pathway
Cervical cancer is one of the most common cancers among women around the world. However, the underlying mechanism involved in cervical cancer progression is incompletely known. In the present study, we determined the role of glycoprotein nonmetastatic melanoma protein B (GPNMB) in tumorigenesis of cervical cancer. According to the GEO database, we found that
Braz J Med Biol Res. Publicado em: 23/11/2018
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19. SSR-Marker assisted evaluation of Genetic Diversity in Mungbean ( Vigna radiata (L.) Wilcezk) genotypes
ABSTRACT Mungbean (Vigna radiata (L.) Wilczek) also known as green gram is an important source of protein in the category of food legumes. In the present study, SSR marker is used to analyze the genetic diversity amongst 23 genotypes of mungbean. Out of a total of 10 primers used for SSR analysis revealed generation of 15 alleles. The number of alleles per l
Braz. arch. biol. technol.. Publicado em: 25/06/2018
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20. Dietary intake of non-dialysis chronic kidney disease patients: the PROGREDIR study. A cross-sectional study
ABSTRACT BACKGROUND: Despite evidence that diet is very important in relation to chronic kidney disease (CKD) progression, studies in this field are scarce and have focused only on some specific nutrients. We evaluated the energy, macronutrient and micronutrient intakes and dietary patterns of non-dialysis CKD participants in the PROGREDIR study. DESIGN A
Sao Paulo Med. J.. Publicado em: 18/06/2018
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21. On thin ice: barriers to adoption of surveillance for patients with stage I testicular seminoma. Survey of US radiation oncologists
ABSTRACT Purpose: Most men with stage I testicular seminoma are cured with surgery alone, which is a preferred strategy per national guidelines. The current pattern of practice among US radiation oncologists (ROs) is unknown. Materials and Methods: We surveyed practicing US ROs via an online questionnaire. Respondent's characteristics, self-rated knowledge
Int. braz j urol.. Publicado em: 2018-06
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22. Oxytocin and arginine vasopressin systems in the domestication process
Abstract Domestication is of unquestionable importance to the technological revolution that has given rise to modern human societies. In this study, we analyzed the DNA and protein sequences of six genes of the oxytocin and arginine vasopressin systems (OXT-OXTR; AVP-AVPR1a, AVPR1b and AVPR2) in 40 placental mammals. These systems play an important role in t
Genet. Mol. Biol.. Publicado em: 26/03/2018
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23. Crotalus durissus terrificus crotapotin naturally displays preferred positions for amino acid substitutions
Abstract Background Classically, Crotalus durissus terrificus (Cdt) venom can be described, according to chromatographic criteria, as a simple venom, composed of four major toxins, namely: gyroxin, crotamine, crotoxin and convulxin. Crotoxin is a non-covalent heterodimeric neurotoxin constituted of two subunits: an active phospholipase A2 and a chaperone p
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 18/12/2017
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24. Expression analysis of the Arabidopsis thaliana AtSpen2 gene, and its relationship with other plant genes encoding Spen proteins
Abstract Proteins of the Split ends (Spen) family are characterized by an N-terminal domain, with one or more RNA recognition motifs and a SPOC domain. In Arabidopsis thaliana, the Spen protein FPA is involved in the control of flowering time as a component of an autonomous pathway independent of photoperiod. The A. thaliana genome encodes another gene for a
Genet. Mol. Biol.. Publicado em: 28/08/2017