Programmed Cell Death
Mostrando 13-24 de 613 artigos, teses e dissertações.
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13. Produção recombinante e caracterização funcional de uma legumaína de cana-de-açúcar
Plant legumains, also termed vacuolar processing enzymes (VPEs), are cysteine peptidases that play key roles in seed maturation, germination, senescence, stress response, programmed cell death during development and defense against pathogens. Despite the increasing number of reports on VPEs, most of studies are on dicotyledonous legumain and their role in se
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 28/02/2012
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14. Differential expression of the costimulatory molecules CD86, CD28, CD152 and PD-1 correlates with the host-parasite outcome in leprosy
Leprosy is a spectral disease exhibiting two polar sides, namely, lepromatous leprosy (LL) characterised by impaired T-cell responses and tuberculoid leprosy in which T-cell responses are strong. Proper T-cell activation requires signalling through costimulatory molecules expressed by antigen presenting cells and their ligands on T-cells. We studied the infl
Mem. Inst. Oswaldo Cruz. Publicado em: 2012-12
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15. Reduced occurrence of programmed cell death and gliosis in the retinas of juvenile rabbits after shortterm treatment with intravitreous bevacizumab
OBJECTIVE: Bevacizumab has been widely used as a vascular endothelial growth factor antagonist in the treatment of retinal vasoproliferative disorders in adults and, more recently, in infants with retinopathy of prematurity. Recently, it has been proposed that vascular endothelial growth factor acts as a protective factor for neurons and glial cells, particu
Clinics. Publicado em: 2012
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16. Vias de sobrevivência e morte em queratinócitos submetidos ao estresse oxidativo e choque hiperosmótico / Survival and death signaling pathways in keratinocytes exposed to oxidative stress and hyperosmotic shock
The epidermis is constantly confronted with multiple environmental stressors. Changes in humidity or exposition to UV radiation affect the redox state and osmotic balance, modifying the physiological characteristics of the skin. In response to different stresses, epidermal keratinocytes can activate distinct signaling pathways and the balance between death a
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 27/06/2011
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17. Miltefosine induces metacaspase and PARP genes expression in Leishmania infantum
OBJECTIVES: Apoptosis is the process of programmed cell death (PCD) that occurs in both animal and plant cells. Protozoan parasites possess metacaspase and these caspase-related proteases could be involved in the PCD pathways in these organisms. Therefore we analyzed the activities of metacaspase and PARP genes in Leishmania infantum (MCAN/IR/96/LON49) treat
Brazilian Journal of Infectious Diseases. Publicado em: 2011-10
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18. Miltefosine induces programmed cell death in Leishmania amazonensis promastigotes
In the current study, we evaluated the mechanism of action of miltefosine, which is the first effective and safe oral treatment for visceral leishmaniasis, in Leishmania amazonensis promastigotes. Miltefosine induced a process of programmed cell death, which was determined by the externalization of phosphatidylserine, the incorporation of propidium iodide, c
Memórias do Instituto Oswaldo Cruz. Publicado em: 2011-06
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19. Theobroma cacao cystatins impair Moniliophthora perniciosa mycelial growth and are involved in postponing cell death symptoms.
Three cystatin open reading frames named TcCys1, TcCys2 and TcCys3 were identified in cDNA libraries from compatible interactions between Theobroma cacao (cacao) and Moniliophthora perniciosa. In addition, an ORF named TcCys4 was identified in the cDNA library of the incompatible interaction. The cDNAs encoded conceptual proteins with 209, 127, 124, and 205
Planta. Publicado em: 2011
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20. Mecanismos envolvidos com a sobrevivência de Xylella fastidiosa em condições de estresse e efeito de N-Acetil-L-Cisteína em seu biofilme / Mechanisms involved in Xylella fastidiosa survival under stress conditions and effect of N-Acetyl-L-Cysteine on its biofilm
Xylella fastidiosa is a Gram-negative bacterium that causes several diseases in different plant species, including citrus variegated chlorosis (CVC) in sweet orange (Citrus sinensis L. Osbeck), whose economic damage is of millions of dollars annually. The symptoms development has been associated with the blockage of xylem vessels caused by bacterial biofilm
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 15/06/2010
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21. Análises moleculares das vias de sinalização de morte celular originadas no retículo endoplasmático / Molecular analyses of cell death pathways signalling originated in the endoplasmic reticulum
Abiotic and biotic stresses are responsible for major losses in agricultural productivity world wise. Therefore, the understanding of mechanisms of plant stress response and adaptation to such conditions should provide the foundation for engineering plant stress tolerance and hence maximizing the yield of crops growing under adverse environmental conditions.
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 11/02/2010
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22. Acute neuronal injury: the role of excitotoxic programmed cell death mechanisms
Brazilian Journal of Pharmaceutical Sciences. Publicado em: 2010-12
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23. Influência da depleção e suplementação mitocondrial no processo de apoptose embrionária / Influence of mitochondrial depletion and suplementation in embryonic apoptosis
Studies developed with bovine zygotes submitted to a decrease of about 50% of the mitochondrial content did not present a deleterious effect on in vitro embryonic development. This model was developed by the centrifugation of zygotes after in vitro fertilization (IVF), removal of the mitochondria enriched cytoplast fraction (MECF) and posterior introduction
Publicado em: 2010
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24. Efeito do extrato de Azadirachta indica (nim) sobre resposta de hipersensibilidade mediada por ácido salicílico em células de Rubus fruticosus / Effect of Azadirachta indica extract (neem) on hypersensitivity response mediated by salicylic acid in cells of Rubus fruticosus.
As plantas, assim como outros organismos, possuem a capacidade de se defenderem contra ataque de patógenos. Uma das respostas desencadeadas pelo reconhecimento do patógeno pelas células vegetais é a reação de hipersensibilidade (RH), que envolve a morte imediata das células do sítio primário de infecção, oferecendo resistência ao crescimento do p
Publicado em: 2010