Porcine Skin
Mostrando 1-12 de 48 artigos, teses e dissertações.
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1. In vitro evaluation of cutaneous penetration of acyclovir from semisolid commercial formulations and relation with its effective antiviral concentration
ABSTRACT The evaluation of drug permeation/penetration of semisolid formulations into animal skin can be useful to supplement the pharmaceutical equivalence. This paper describes the in vitro assessment of acyclovir (ACV) into porcine skin from commercial formulations with etermination of drug concentration in different layers of cutaneous tissue to correlat
Braz. J. Pharm. Sci.. Publicado em: 2016-09
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2. Skin microcirculatory changes reflect early the circulatory deterioration in a fulminant sepsis model in the pig
PURPOSE: In the pathophysiology of sepsis tissue perfusion dysfunction is a crucial driving force. Thus the early recognition is highly important. Concerning the early hours of bacteremia, and the systemic inflammatory response reaction leading to sepsis we aimed to investigate the micro- and macrocirculatory changes. METHODS: In 20 juvenile Hungahib pigs w
Acta Cir. Bras.. Publicado em: 2015-07
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3. Efficacy of Pelvisoft® Biomesh for cystocele repair: assessment of long-term results
Introduction and Hypothesis To our knowledge a study regarding the efficacy of Pelvisoft® Biomesh for cystocele repair has not previously been reported in the literature. The aim of our study was to assess the long-term efficacy, subjective outcomes and complications in the use of a non-synthetic porcine skin mesh graft (Pelvisoft® Biomesh) associated w
Int. braz j urol.. Publicado em: 2014-12
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4. Desenvolvimento e caracterização de dispositivo de PLLA/Trietil-Citrato associado à derme suína acelular para reparação de lesões cutâneas / Development and characterization of PLLA/Triethyl citrate device associated to acellular dermal matrix to repair cutanous wounds
One of the challenges of the Tissue Engineering is to promote a better functioning of organs and tissues damaged by diseases or traumas. With target for developing a biphasic device for future regeneration and dermal application in Tissue Engineering and Regenerative Medicine, fibroblasts from VERO cell line were cultivated on a porcine acellular dermal matr
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 15/02/2012
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5. New ex-vivo organ model for percutaneous renal surgery
OBJECTIVES: Percutaneous Renal Surgery (PRS) is a demanding procedure and success is mostly hampered by the lacking of training facilities. Thus, the purpose of the study was to evaluate a significantly improved pre-existing porcine kidney-training model for percutaneous renal access and PRS. MATERIALS AND METHODS: A biologic training model using porcine kid
International braz j urol. Publicado em: 2011-06
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6. Laser de baixa intensidade no tratamento de úlceras cutâneas aplicando curativos de pericárdio porcino revestido com quitosana / Low level laser therapy for treatment of skin ulcers by applying dressings porcine pericardium coated with chitosan
As lesões na pele, quando extensas, representam um grande problema de saúde pública e elevados custos associados aos tratamentos. A laserterapia tem sido aplicada por décadas a fim de acelerar o processo de cicatrização cutânea. Já a matriz de pericárdio porcino apresenta potencial para ser utilizado como curativo biológico, porém o patch tem ráp
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 17/12/2010
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7. Porcine skin as a source of biodegradable matrices: alkaline treatment and glutaraldehyde crosslinking
In this work, the modifications promoted by alkaline hydrolysis and glutaraldehyde (GA) crosslinking on type I collagen found in porcine skin have been studied. Collagen matrices were obtained from the alkaline hydrolysis of porcine skin, with subsequent GA crosslinking in different concentrations and reaction times. The elastin content determination showed
Polímeros. Publicado em: 07/05/2010
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8. Determination of rutin and narcissin in marigold extract and topical formulations by liquid chromatography: applicability in skin penetration studies
A chromatographic technique for determination of rutin and narcissin in marigold extract and topical formulations was developed and validated. The method shows linearity over the concentration range of 0.2 - 6.0 μg/mL of rutin (r = 0.9986) and 0.8 - 12.0 μg/mL of narcissin (r = 0.9951). The values obtained for precision and accuracy are in agreement with I
Química Nova. Publicado em: 2010
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9. Metodologia analítica aplicada ao controle de qualidade do antifúngico cloridrato de butenafina na forma de creme e à avaliação da sua penetração cutânea in vitro / Analytical methodology applied to the quality control of the antifungal butenafine hydrochloride in cream formulation and to the analysis of its penetration in vitro
Objectives: The aim of the present work was to develop, validate and compare stability indicating methods to quantify butenafine hydrochloride (BTF), raw material and commercial cream, as well as to establish the degradation kinetics of the drug in a stress condition. Also, the study had the goal of validating a method to assess and compare the cutaneous per
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 2010
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10. Mineralização in vitro de matrizes de colágeno aniônico derivadas de tecidos biológicos / In vitro mineralization of anionic collagen matrices
The reconstruction of osseous defects is still a problem that affects millions of people and medicine tries to solve it. One alternative to solve these problems has been the development of biomaterials that can be used as inductors in the osseous repair process. Collagen is a natural polymer able to promote healing and bone regeneration, and among hydroxyapa
Publicado em: 2008
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11. "Pele porcina como fonte de matrizes tridimensionais de colágeno" / "Porcine skin as a source of tridimensional collagen scaffolds"
As lesões cutâneas e queimaduras são considerados os principais causadores de danos e perdas dos tecidos moles. Em casos severos de trauma, os processos naturais de regeneração são insuficientes no reparo dos danos, resultando em lesões cutâneas crônicas. A desvitalização de matrizes homólogas ou heterólogas é uma alternativa para a produção
Publicado em: 2006
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12. Collagen matrices behavior in treatment of skin rat wounds / Comportamento de matrizes de colágeno utilizadas no tratamento de feridas planas induzidas em pele de rato
The potentiality of the use of a collagen based matrix and of a cream prepared by the mixture of a commercial cream plus collagen (90:10 w/w) were evaluated in the healing process of rats skin. The acellular collagen matrix and the collagen gel were obtained by an alkaline treatment of porcine serosa which does not damage the native collagen structure and
Publicado em: 2005