Polymeric Nanoparticles
Mostrando 13-24 de 77 artigos, teses e dissertações.
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13. POLÍMERO BIODEGRADÁVEL ANTIMICROBIANO ATRAVÉS DA ADITIVAÇÃO COM COMPOSTOS À BASE DE ZINCO
Antimicrobial packaging is a promising type of active packaging, which has an antimicrobial agent incorporated into the polymer matrix, capable to eliminate or inhibit deteriorating and/or pathogenic microorganisms. The zinc compounds are antimicrobial agents commonly used to confer this feature. The objective of this work was to evaluate the antimicrobial a
Quím. Nova. Publicado em: 2018-04
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14. Nanostructured magnetic alginate composites for biomedical applications
Abstract This is a study of the preparation and characterization of polymeric-magnetic nanoparticles. The nanoparticles used were magnetite (Fe3O4) and the chosen polymers were alginate and chitosan. Two types of samples were prepared: uncoated magnetic nanoparticles and magnetic nanoparticles encapsulated in polymeric matrix. The samples were analyzed by XR
Polímeros. Publicado em: 2017-12
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15. Development and Validation of a Stability-Indicating Method for Perillyl Alcohol Incorporated in Poly(lactide-co-glycolide) Nanoparticles and Stress Degradation Studies
Perillyl alcohol has been studied in the treatment of cancer disease. However, its high toxicity is a drawback, which can be overcome by its incorporation in nanostructured systems. The aim of this work was to develop and validate a chromatographic method for determination of perillyl alcohol encapsulation efficiency in a polymeric nanoparticles formulation
J. Braz. Chem. Soc.. Publicado em: 2017-12
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16. Nano-Sized Silver Colloids Produced and Stabilized by Amino-Functionalized Polymers: Polymer Structure-Nanoparticle Features and Polymer Structure-Growth Kinetics Relationships
The synthesis of highly stable silver colloids has been successfully achieved by using reducing/stabilizer amino-functionalized polymers without the aid of any other external agent. The polymer coated inorganic nanoparticles have been detailed characterized via scattering, imaging and UV-Vis spectroscopy. The combination of transmission electron microscopy (
J. Braz. Chem. Soc.. Publicado em: 2017-09
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17. Evaluation of polymeric PLGA nanoparticles conjugated to curcumin for use in aPDT
ABSTRACT Antimicrobial photodynamic therapy (aPDT) involves the association of a photosensitizing agent with a light source with the goal of causing apoptosis or microbial lysing. The use of compounds with natural active principles is gaining prominence throughout the world. Several studies from groups that are linked to the development of innovations in the
Braz. J. Pharm. Sci.. Publicado em: 20/07/2017
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18. Determination of Chlorophenol in Environmental Samples Using a Voltammetric Biosensor Based on Hybrid Nanocomposite
In this work, a simple electrochemical biosensor for 4-chlorophenol was developed based on laccase immobilized on a hybrid nanocomposite (ZnO nanoparticles/chitosan), and incorporated in a carbon paste electrode. There are few biosensors in the literature for this specific pollutant because it tends to form polymeric films on the electrode, causing surface p
J. Braz. Chem. Soc.. Publicado em: 2017-07
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19. A simple HPLC method for the determination of halcinonide in lipid nanoparticles: development, validation, encapsulation efficiency, and in vitro drug permeation
ABSTRACT Halcinonide is a high-potency topical glucocorticoid used for skin inflammation treatments that presents toxic systemic effects. A simple and quick analytical method to quantify the amount of halcinonide encapsulated into lipid nanoparticles, such as polymeric lipid-core nanoparticles and solid lipid nanoparticles, was developed and validated regard
Braz. J. Pharm. Sci.. Publicado em: 22/06/2017
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20. Ameliorating the antitumor activity of lenalidomide using PLGA nanoparticles for the treatment of multiple myeloma
Abstract Lenalidomide (LND) is an anti-cancer drug and an effective derivative of thalidomide used for multiple myeloma therapy. Because of its poor solubility in water, LND is known to cause low oral bioavailability (below 33%), and as a direct consequence of this, the dosing frequency is extended thus increasing risk of toxicity. To improve its bioavailabi
Braz. J. Pharm. Sci.. Publicado em: 22/06/2017
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21. Preparation of mupirocin-loaded polymeric nanocapsules using essential oil of rosemary
Abstract The purpose of this study was to prepare and characterize mupirocin-loaded polymeric nanocapsules using two different oils and to develop and validate an analytical method for quantitative determination by high performance liquid chromatography. The mean size of the nanoparticles was 233.05 nm and 275.03 nm for nanocapsules with a rosemary oil like
Braz. J. Pharm. Sci.. Publicado em: 20/04/2017
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22. BIOMATERIAIS PARA FORMULAÇÕES DE BASE NANOTECNOLÓGICA VISANDO TERAPIA GENÉTICA OCULAR
Gene therapy is a promising tool for the treatment of ocular diseases. Nevertheless, there are some import limitations, especially related to the ocular route and the characteristics of nucleic acids that must be overcome to ensure the success of the therapy. In this context, nanotechnology-based carriers such as nanoemulsions, nanoparticles, dendrimers and
Quím. Nova. Publicado em: 2017-01
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23. ANALYSIS OF THERMAL AND AQUEOUS SUSPENSION STABILITIES OF CHITOSAN BASED NANOENCAPSULATED VITAMINS
The food nutritional content is reduced as result of vitamins degradation. In order to minimize such losses, the encapsulation technique into polymeric nanoparticles (NPs) could offer an additional protection, extending the stability. The crosslinking formed by the ionic gelation process of chitosan and tripolyphosphate (Chi-TPP) has been widely used as an e
Quím. Nova. Publicado em: 2016-11
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24. Preparation of Polymeric Micelles of Poly(Ethylene Oxide-b-Lactic Acid) and their Encapsulation With Lavender Oil
Nanoparticles comprised of the poly(ethylene oxide)-b-poly (lactic acid) diblock copolymer (PEO-b-PLA) with and without the incorporation of lavender oil were prepared by nanoprecipitation. Diblock copolymers based on a fixed PEO block (5KDa) and two different PLA segments (4.5 or 10KDa) were used. The morphology, encapsulation efficiency, essential oil-poly
Mat. Res.. Publicado em: 03/10/2016