Pituitary Tumor
Mostrando 13-24 de 208 artigos, teses e dissertações.
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13. Expression of E-cadherin, Slug and NCAM and its relationship to tumor invasiveness in patients with acromegaly
Pituitary adenomas account for 10–15% of primary intracranial tumors. Growth hormone (GH)-secreting adenomas account for 13% of all pituitary adenomas and cause acromegaly. These tumors can be aggressive, invade surrounding structures and are highly recurrent. The objective of this study was to evaluate E-cadherin, Slug and neural cell adhesion molecule (N
Braz J Med Biol Res. Publicado em: 11/12/2017
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14. Long-term follow-up of patients with elevated IGF-1 and nadir GH > 0.4 µg/L but < 1 µg/L
ABSTRACT Objective To report the results of initial investigation and after 5 years of patients with a suspicious clinical scenario for acromegaly, elevated IGF-1, and nadir GH during an oral glucose tolerance test (OGTT) > 0.4 µg/L but < 1 µg/L. Subjects and methods Seventeen patients who had elevated IGF-1 (outside puberty and pregnancy) in two measu
Arch. Endocrinol. Metab.. Publicado em: 18/09/2017
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15. A rare case of ectopic ACTH syndrome originating from malignant renal paraganglioma
SUMMARY Ectopic adrenocorticotropic hormone (ACTH) syndrome is characterized by hypercortisolism due to the hypersecretion of a non-pituitary ACTH-secreting tumor leading to Cushing’s syndrome. Only a few cases have been reported previously as causing ectopic ACTH related to paraganglioma. Herein, we present a case of Cushing’s syndrome, in who was prove
Arch. Endocrinol. Metab.. Publicado em: 13/02/2017
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16. Endoscopic versus microscopic transsphenoidal surgery in the treatment of pituitary tumors: systematic review and meta-analysis of randomized and non-randomized controlled trials
ABSTRACT We conducted a systematic review and meta-analysis of randomized and non-randomized controlled trials that compared pure endoscopic with microscopic transsphenoidal surgery (TSS) in the resection of pituitary tumors. Embase, PubMed, Lilacs, and Central Cochrane were used as our data sources. The outcomes were total tumor resection, achievement of bi
Arch. Endocrinol. Metab.. Publicado em: 05/09/2016
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17. Incidence and prevalence of clinically relevant pituitary adenomas: retrospective cohort study in a Health Management Organization in Buenos Aires, Argentina
ABSTRACT Objectives The main purpose of this study was to estimate the incidence rate and prevalence of clinically relevant pituitary adenomas (PAs) within the Hospital Italiano Medical Care Program (HIMCP), a well-defined population of 150,000 members living in the urban and suburban area of the city of Buenos Aires. We defined clinically relevant PAs as
Arch. Endocrinol. Metab.. Publicado em: 25/08/2016
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18. Pituitary metastasis of lung neuroendocrine carcinoma: case report and literature review
SUMMARY Metastasis to the pituitary gland is an unusual situation in clinical practice, but the frequency thereof is increasing due to the increased survival of cancer patients, and greater availability of imaging. In most cases, they are found between the sixth and seventh decades of life, as determined in image examination of patients with known malignant
Arch. Endocrinol. Metab.. Publicado em: 2015-12
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19. PROP1 overexpression in corticotrophinomas: evidence for the role of PROP1 in the maintenance of cells committed to corticotrophic differentiation
OBJECTIVE: The expression of transcription factors involved in early pituitary development, such as PROP1 and POU1F1, has been detected in pituitary adenoma tissues. In this study, we sought to characterize the transcriptional profiles of PROP1, POU1F1, and TBX19 in functioning and nonfunctioning pituitary adenomas in an attempt to identify their roles in t
Clinics. Publicado em: 2013-06
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20. AVALIAÇÃO DAS COMPLICAÇÕES PÓS-OPERATÓRIAS IMEDIATAS DOS PACIENTES SUBMETIDOS À CIRURGIA DE TUMOR DE HIPÓFISE / EVALUATION OF POSTOPERATIVE COMPLICATIONS IMMEDIATE OF PATIENTS UNDERGOING SURGERY OF TUMOR OF PITUITARY
Os adenomas hipofisários são a causa mais comum de massa selar da terceira década em diante, sendo responsável por mais de 10% das neoplasias intracranianas. Estudos recentes apontam para uma prevalência de até 77,6 por 100.000 habitantes. A ressecção cirúrgica pode ser necessária e as complicações pós-operatórias de cirurgia hipofisária inclu
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 30/07/2012
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21. ANÁLISE DA EXPRESSÃO DOS RECEPTORES DA SOMATOSTATINA (SST1-5) E DA DOPAMINA (DR2) EM ADENOMAS HIPOFISÁRIOS / ANALYSIS OF EXPRESSION OF THE RECEPTORS OF THE SOMATOSTATIN (SST1-5) AND DOPAMINE (DR2) IN PITUITARY ADENOMAS
Pituitary tumors represent 15% of intracranial neoplasms and are usually benign. The treatment primary is surgical resection with exception for prolactinomas because dopamine agonists are very effective in the treatment these tumors. If surgery does not lead to healing, it is necessary other therapeutic strategy in a attempt to control hormone levels and tum
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 12/03/2012
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22. RNAi-mediated knockdown of pituitary tumor- transforming gene-1 (PTTG1) suppresses the proliferation and invasive potential of PC3 human prostate cancer cells
Pituitary tumor-transforming gene-1 (PTTG1) is a proto-oncogene that promotes tumorigenesis and metastasis in numerous cell types and is overexpressed in a variety of human tumors. We have demonstrated that PTTG1 expression was up-regulated in both human prostate cancer specimens and prostate cancer cell lines. For a more direct assessment of the function of
Braz J Med Biol Res. Publicado em: 2012-11
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23. Variable clinical expression in patients with a germline MEN1 disease gene mutation: clues to a genotype-phenotype correlation
Multiple endocrine neoplasia type 1 is an inherited endocrine tumor syndrome, predominantly characterized by tumors of the parathyroid glands, gastroenteropancreatic tumors, pituitary adenomas, adrenal adenomas, and neuroendocrine tumors of the thymus, lungs or stomach. Multiple endocrine neoplasia type 1 is caused by germline mutations of the multiple endoc
Clinics. Publicado em: 2012
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24. A link between sleep loss, glucose metabolism and adipokines
The present review evaluates the role of sleep and its alteration in triggering problems of glucose metabolism and the possible involvement of adipokines in this process. A reduction in the amount of time spent sleeping has become an endemic condition in modern society, and a search of the current literature has found important associations between sleep los
Brazilian Journal of Medical and Biological Research. Publicado em: 2011-10