Piperine
Mostrando 1-12 de 23 artigos, teses e dissertações.
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1. OBSERVAÇÃO DE HOMODÍMERO DO TIPO BIS-1,3-BENZODIOXONA SINTETIZADO VIA METÁTESE DE OLEFINAS DA PIPERINA CATALISADA POR PRÉ-CATALISADORES DE RU(II) NÃO COMERCIAIS
LN-1 and LN-2 are two Ru(II) complexes coordinated to the phosphine and amines simultaneously, each with two chlorides. PPh3 is the phosphine and the amine is piperidine (LN-1) and perhydroazepine (LN-2). The two compounds are complexes five-coordinated square pyramidal geometry, with the amine in the axial plane. LN-1 and LN-2 were tested for the first time
Química Nova. Publicado em: 2022
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2. Synthesis, Spectroscopic Characterization, DFT Calculations and Preliminary Antifungal Activity of New Piperine Derivatives
Four new piperine derivatives, PC1-PC4, were synthesized, and their structures were fully characterized by infrared (IR) and 1H and 13C nuclear magnetic resonance (NMR) spectroscopies. Quantum chemical calculations were performed using density functional theory (DFT) with the B3LYP-D3/6-31G(d,p) and 6-311+G(2d,p) basis sets. Electronic properties, such as th
J. Braz. Chem. Soc.. Publicado em: 2021-03
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3. Synthesis, in silico Study and Antimicrobial Activity of New Piperine Derivatives Containing Substituted δ-Esters
A series of fifteen new piperine-derived diesters was synthesized through the substitution reaction between the salt of piperic acid, obtained through piperine basic hydrolysis, with the δ-chloro-esters, obtained through the cleavage of tetrahydrofuran (THF) with acyl chlorides in the presence of ZnCl2. The final compounds were obtained with yields ranging
J. Braz. Chem. Soc.. Publicado em: 2020-12
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4. New Diesters Derived from Piperine: in silico Study and Evaluation of Their Antimicrobial Potential
Piperine, previously extracted from black pepper (Piper nigrum L.), was used as a precursor for the synthesis of twelve new diester derivatives. The final products were obtained through the bimolecular nucleophilic substitution reaction (SN2) of the alkyl 2-chloroacetates and the salt of piperic acid, obtained from the basic hydrolysis of piperine. The compo
J. Braz. Chem. Soc.. Publicado em: 2020-08
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5. Performance, Carcass Traits, Biochemical and Hematological Profile, Ileal Microbiota and Nutrient Metabolizability in Broilers Fed Diets Containing Cell Wall of Saccharomyces Cerevisiae and Piperine
ABSTRACT The objective of this study was to evaluate the inclusion of cell wall of Saccharomyces cerevisiae (CWSc) and piperine in broiler rations and their effects on performance, carcass traits, blood parameters, ileal microbiota and nutrient digestibility. A randomized block design with five treatments and six replicates of 10 birds was used, totaling 300
Braz. J. Poult. Sci.. Publicado em: 05/12/2019
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6. Perspectives and Applications of Natural Products as Civilian Defense Devices
Civilian defense devices are physical and chemical artefacts used to incapacitate an aggressor without causing death or injury. As city violence increases, safety feelings became worst and a growing commercial demand for these materials supply faces technologically challenges not only to riot control but also to self-protection. Controversies on the use of t
J. Braz. Chem. Soc.. Publicado em: 23/05/2019
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7. Optimization for extraction of an oil recipe consisting of white pepper, long pepper, cinnamon, saffron, and myrrh by supercritical carbon dioxide and the protective effects against oxygen–glucose deprivation in PC12 cells
ABSTRACT This study is to investigate the most efficient extractives of extracting oil recipe for stroke treatment and the protective effects on an oxygen and glucose deprivation model in PC12 cells. An orthogonal experimental design L9 (34) was carried out for oil recipe's optimization with supercritical CO2 fluid extraction. 2-(4,5-Dimethylthiazol-2-yl)-2,
Rev. bras. farmacogn.. Publicado em: 2018-06
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8. Hepatoprotective effect of Aegle marmelos augmented with piperine co-administration in paracetamol model
ABSTRACT The current study explored hepatoprotective effect of Aegle marmelos (L.) Corrêa, Rutaceae, leaves extract. Potentiation of A. marmelos hepatoprotective effect with piperine co-administration was also explored. Wistar rats were randomly divided into seven groups: (i) normal control, (ii) paracetamol group, (iii) silymarin group, (iv) extract-25 gro
Rev. bras. farmacogn.. Publicado em: 2018-01
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9. Anti-inflammatory activity and chemical composition of dichloromethane extract from Piper nigrum and P. longum on permanent focal cerebral ischemia injury in rats
Abstract White pepper (Piper nigrum L.) and long pepper (Piper longum L.) belong to family Piperaceae and are commonly used as household spices and traditional medicine worldwide, specifically in China and Southeast Asia. In Traditional Chinese Hui Medicine, these herbs are widely used for treatment of stroke. Our present study investigated effects of these
Rev. bras. farmacogn.. Publicado em: 2017-06
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10. A biodegradable device for the controlled release of Piper nigrum (Piperaceae) standardized extract to control Aedes aegypti (Diptera, Culicidae) larvae
Abstract: INTRODUCTION: The significant increase in dengue, Zika, and chikungunya and the resistance of the Aedes aegypti mosquito to major insecticides emphasize the importance of studying alternatives to control this vector. The aim of this study was to develop a controlled-release device containing Piper nigrum extract and to study its larvicidal activi
Rev. Soc. Bras. Med. Trop.. Publicado em: 2016-12
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11. Local Anesthetic Activity from Extracts, Fractions and Pure Compounds from the Roots of Ottonia anisum Spreng. (Piperaceae)
ABSTRACT Piperaceae species can be found worldwide in tropical and subtropical areas and many of them have been used for centuries in traditional folk medicine and in culinary. In Brazil, species of Piperaceae are commonly used in some communities as local anesthetic and analgesic. Countrified communities have known some species of the genus Ottonia as "anes
An. Acad. Bras. Ciênc.. Publicado em: 2016-12
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12. A influência da piperina na biodisponibilidade de fármacos: uma abordagem molecular
Piperine is the major alkaloid of Piper nigrum Linn., used as a spice and in folk medicine. We present a molecular docking study supporting experimental data on the enhancement in bioavailability of propranolol, theophylline, phenytoin, nevirapine, nimesulide, pyrazinamide, carbamazepine, and spartein in the presence of piperine. The complex formed with pipe
Quím. Nova. Publicado em: 2014