Piperine
Mostrando 13-23 de 23 artigos, teses e dissertações.
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13. Rapid validated HPTLC method for estimation of piperine and piperlongumine in root of Piper longum extract and its commercial formulation
Piperine and piperlongumine, alkaloids having diverse biological activities, commonly occur in roots of Piper longum L., Piperaceae, which have high commercial, economical and medicinal value. In present study, rapid, validated HPTLC method has been established for the determination of piperine and piperlongumine in methanolic root extract and its commercial
Rev. bras. farmacogn.. Publicado em: 20/09/2012
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14. The combined action of phytolarvicides for the control of dengue fever vector, Aedes aegypti
Amongst other botanical sources, Annona muricata L., Annonaceae, seeds and Piper nigrum L., Piperaceae, fruits are particularly enriched with acetogenins and piperine-related amides, respectively. These crude ethanolic extracts are potent Aedes aegypti bioactives that can kill Aedes aegypti larvae (dengue fever mosquito). A. muricata displayed a 93.48 µg/mL
Revista Brasileira de Farmacognosia. Publicado em: 2012
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15. Supressão de estímulo nociceptivo na articulação temporomandibular de ratos fêmeas usando piperina / Experimental model for suppression of nociceptive stimuli in the TMJ of rats with piperine
As articulações temporomandibulares (ATM) podem ser afetadas por alterações articulares e/ou musculares que podem progredir e iniciar mudanças degenerativas, culminando em osteoartrite (OA). A liberação de mediadores químicos, durante processo inflamatório na ATM, pode modular a condução dos estímulos nociceptivos e promover a expansão e agravam
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 09/09/2011
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16. Oral administration of piperine for the control of aflatoxin intoxication in rats
Aflatoxins are mycotoxins that have important toxic effects on human and animal health, even if consumed at low doses. The oral administration of piperine (1.12 mg/kg) during 23 days in rats seemingly interfered with the toxicity of aflatoxins, decreasing hepatic injuries and the leukocyte depletion in experimentally intoxicated animals.
Brazilian Journal of Microbiology. Publicado em: 2010-06
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17. SÍNTESE E AVALIAÇÃO DE ATIVIDADE TRIPANOCIDA DE NOVOS HETEROCICLOS DA CLASSE DOS 1,2,4-OXADIAZÓIS, DERIVADOS E ANÁLOGOS DA AMIDA NATURAL PIPERINA. / SUMMARY AND EVALUATION OF NEW trypanocidal activity Heterocycles CLASS OF 1,2,4-OXADIAZÓIS, DERIVATIVES AND ANALOGS OF NATURAL AMIDA piperine.
Este trabalho se insere numa linha de pesquisa que visa a utilização de produtos naturais abundantes e accessíveis na síntese de novas moléculas com potencial atividade anti-chagásica. Estudos recentes em nosso laboratório demonstraram a atividade antiparasitária da piperina e de uma série de derivados e análogos sobre o Trypanosoma cruzi, agente e
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 25/09/2009
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18. Biomimetic oxidative studies with the natural products piperine and piplartine. / Estudos oxidativos biomiméticos com os produtos naturais piperina e piplartina
Piperine and piplartine are alkaloids isolated from species of Piper genus. The choice of these molecules for this study was based on the promising biological activities presented by these substances, especially for their antitumoral potential. Based on the research of alternative ways for studying the metabolism of new drugs, especially from natural product
Publicado em: 2008
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19. Effect of piperine on experimental intoxication by aflatoxinas in rats. / Ação da piperina sobre a intoxicação experimental de ratos por aflatoxinas.
Piperine (1- piperoyl piperidine) main black pepper (Pipper nigrum Linn.) and long pepper (Piper longum Linn.) alkaloid presents several pharmacological and biochemical effects as enzymes inhibition from hepatic metabolism interfering on xenobiotics and pro-carcinogenic substances biotransformation activated by P-450 cytochromo cycle. According to the scient
Publicado em: 2007
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20. Effects of the piperine in broiler chickens (Gallus gallus) with experimental aflatoxins intoxication. / Efeitos da piperina em frangos de corte (Gallus gallus) com intoxicação experimental por aflatoxinas.
Este trabalho teve como objetivo analisar a interferência da administração da piperina em frangos de corte com intoxicação prolongada por aflatoxinas. O experimento foi realizado em duas fases: (i) os frangos foram separados em quatro grupos teste (n=15 aves/ grupo), que receberam diferentes concentrações de piperina (1,12; 2,25 e 4,5mg/kg por via ora
Publicado em: 2007
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21. In vivo growth-inhibition of Sarcoma 180 by piplartine and piperine, two alkaloid amides from Piper
Piplartine {5,6-dihydro-1-[1-oxo-3-(3,4,5-trimethoxyphenyl)-2-propenyl]-2(1H)pyridinone} and piperine {1-5-(1,3)-benzodioxol-5-yl)-1-oxo-2,4-pentadienyl]piperidine} are alkaloid amides isolated from Piper. Both have been reported to show cytotoxic activity towards several tumor cell lines. In the present study, the in vivo antitumor activity of these compoun
Brazilian Journal of Medical and Biological Research. Publicado em: 2006-06
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22. Anticancer potential of piplartine and piperine, amides isolated from piper species / Potencial anticâncer da piplartina e da piperina, amidas isoladas de plantas do gênero piper
Piplartine and piperine are alkaloids/amides isolated from Piper species. The activity of these compounds was initially evaluated on the brine shrimp lethality assay, sea urchin development, MTT assay using tumor cell lines, and hemolytic assay. Piperine showed a higher toxicity in brine shrimp than piplartine. Both piplartine and piperine inhibited the sea
Publicado em: 2005
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23. Aspergillus parasiticus growth and aflatoxin production on black and white pepper and the inhibitory action of their chemical constituents.
Aspergillus parasiticus Speare NRRL 2999 growth and aflatoxin production in black and white pepper and the penetration of the fungus in black pepper corn over various incubation periods were studied. Also, the effects of piperine and pepper oil on growth and aflatoxin production were studied. Under laboratory conditions, black and white pepper supported afla