Phospholipid Vesicles
Mostrando 1-12 de 339 artigos, teses e dissertações.
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1. Distribution of Xanthene Dyes in DPPC Vesicles: Rationally Accounting for Drug Partitioning Using a Membrane Model
The correct selection of a dye that has effective action as a photosensitizer is a primary concern for successful therapeutic outcomes. The effectiveness of the photodynamic agent is related to both the targeting of cell membranes and the photochemical yield of the chosen dye. The distributions of xanthene derivatives Eosin Y, Erythrosin B, and Rose Bengal B
J. Braz. Chem. Soc.. Publicado em: 2016-11
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2. Liposome and Their Applications in Cancer Therapy
ABSTRACT Liposomes, the vesicles of phospholipid bilayer, can encapsulate both hydrophilic and lipophilic drugs and protect them from degradation. Liposomes have been extensively studied and continue to create intense interest in research since their discovery in the mid-1960s. Since then, liposomes have been considered to be the most successful nanocarriers
Braz. arch. biol. technol.. Publicado em: 08/03/2016
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3. Antioxidant effect of 4-nerolidylcatechol and α-tocopherol in erythrocyte ghost membranes and phospholipid bilayers
4-Nerolidylcatechol (4-NC) is found in Pothomorphe umbellataroot extracts and is reported to have a topical protective effect against UVB radiation-induced skin damage, toxicity in melanoma cell lines, and antimalarial activity. We report a comparative study of the antioxidant activity of 4-NC and α-tocopherol against lipid peroxidation initiated by two fre
Braz J Med Biol Res. Publicado em: 06/09/2013
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4. Dispersões lipídicas de dimiristoil fosfatidilglicerol: um estudo termo-estrutural / Lipid dispersions of dymiristoyl phosphatidylglycerol: a thermo-structural study
Dispersions of the saturated anionic phospholipid dimyristoyl phosphatidyl glycerol (DMPG) have been extensively studied regarding their peculiar thermo-structural behavior. At low ionic strength, the gel-fluid transition is spread along nearly 17 ºC, displaying several thermal events in the calorimetric profile, quite different from the single sharp peak a
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 21/12/2010
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5. Desenvolvimento e farmacocinética de antimônio encapsulado em lipossomas de fosfatidilserina utilizando radioisótopos em leishmaniose experimental / Development and pharmacokinetic of antimony encapsulated in liposomes of phosphatidylserine using radioisotopes in experimental leishmaniasis
Leishmaniases are a complex of parasitic diseases caused by intramacrophage protozoa of the genus Leishmania, and is fatal if left untreated. Pentavalent antimonials, though toxic and their mechanism of action being unclear, remain the first-line drugs for treatment. Effective therapy could be achieved by delivering antileishmanial drugs to these sites of in
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 19/03/2010
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6. Proteoliposomes as matrix vesicles' biomimetics to study the initiation of skeletal mineralization
During the process of endochondral bone formation, chondrocytes and osteoblasts mineralize their extracellular matrix by promoting the formation of hydroxyapatite (HA) seed crystals in the sheltered interior of membrane-limited matrix vesicles (MVs). Ion transporters control the availability of phosphate and calcium needed for HA deposition. The lipidic micr
Brazilian Journal of Medical and Biological Research. Publicado em: 2010-03
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7. Measurement of annexin V uptake and lactadherin labeling for the quantification of apoptosis in adherent Tca8113 and ACC-2 cells
Phosphatidylserine (PS) exposure occurs during the cell death program and fluorescein-labeled lactadherin permits the detection of PS exposure earlier than annexin V in suspended cell lines. Adherent cell lines were studied for this apoptosis-associated phenomenon to determine if PS probing methods are reliable because specific membrane damage may occur duri
Brazilian Journal of Medical and Biological Research. Publicado em: 2008-09
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8. Development of membrane biosensors and characterization of the interactions between cytochrome c and hybrid bilayer membranes by Surface Plasmon Resonance / Desenvolvimento de biosensores de membranas e caracterização da interação entre citocromo c e bicamadas híbridas por ressonância plasmônica de superfície
The aim of this work was to develop membrane biosensors based on Surface Plasmon Resonance (SPR) and to apply them to study the interactions between cytochrome c (cyt c) and model membranes. SPR is an optical technique that provides high-sensitivity measurements of refractive index (n), allowing the characterization of the adsorption and desorption of molecu
Publicado em: 2008
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9. Técnicas de fluorescência no monitoramento de membranas modelo / Fluorescence techniques to monitor model membranes
Apresentamos os resultados de estudos sobre a utilização de técnicas baseadas no fenômeno de fluorescência para a investigação de processos relacionados a membranas modelo. Nessa investigação, estão envolvidas medidas de propriedades espectrais de absorção e emissão de luz por cromóforos adequados, determinação xperimental de perfis de decaim
Publicado em: 2008
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10. Estratégias para prospecção e predição de peptídeos bioativos
Chapters one and two deal with the isolation and identification of bioactive peptides from the skin secretion of Phyllomedusa hypochondrialis. The first chapter demonstrates the use of protemic techniques, mainly mass spectrometry, for the study of bradykinin related peptides (BRPs) present in the amphibians secretion and freshly dissected skin fragments. Ei
Publicado em: 2007
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11. Effect of metallic pollutants in marine algae pigments contents and evaluation of carotenes structural features in mimetic membranes / Efeito de poluentes metálicos nos níveis de pigmentos fotossintéticos presentes em algas marinhas e avaliação do papel estrutural de carotenos em membranas miméticas
This work involves the study of the levels of photosynthetic pigments, carotenoids and chlorophylls, contained in the marine algae Tetraselmis gracilis and Gracilaria tenuistipitata, under conditions of cellular senescence and anthropogenic stress (metallic pollution). Due to the fundamental organizational role of carotenoids in thylakoid membranes, its stru
Publicado em: 2007
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12. Adiabatic differential scanning calorimetric study of divalent cation induced DNA - DPPC liposome formulation compacted for gene delivery
Complexes between nucleic acids and phospholipid vesicles have been developed as stable non-viral gene delivery vehicles. Currently employed approach uses positively charged lipid species and a helper zwitterionic lipid, the latter being applied for the stabilization of the whole complex. However, besides problematic steps during their preparation, cationic
Brazilian Archives of Biology and Technology. Publicado em: 2004-11