Pharmacological Research
Mostrando 1-12 de 160 artigos, teses e dissertações.
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1. BIOMARCADORES MOLECULARES DE DOENÇAS HUMANAS: CONCEITOS FUNDAMENTAIS, MODELOS DE ESTUDO E APLICAÇÕES CLÍNICAS
Molecular biomarkers correspond to all endogenous or exogenous biomolecules, whose presence or alteration in metabolic pathways indicate the response of a biological system to a disturbance caused by internal or external factors. The search for biomarkers has allowed deepening the knowledge of complex pathophysiological mechanisms of diseases, interactions w
Química Nova. Publicado em: 2022
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2. Treatment-resistant bipolar depression: concepts and challenges for novel interventions
Treatment-resistant bipolar depression (TRBD) has been reported in about one-quarter of patients with bipolar disorders, and few interventions have shown clear and established effectiveness. We conducted a narrative review of the published medical literature to identify papers discussing treatment-resistant depression concepts and novel interventions for bip
Brazilian Journal of Psychiatry. Publicado em: 2022
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3. Ethanol and aqueous extracts characterization from guava (Psidium guajava L.) and avocado (Persea americana Mill.) residues
Abstract In Mexico, avocado and guava production generate agronomic residues that contain bioactive compounds as secondary metabolites produced in plants. Their consumption offer favourable health effects; therefore, the objective of the present research was to characterize the bioactive compounds and antioxidant properties in guava (Psidium guajava L.) and
Food Sci. Technol. Publicado em: 2021-09
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4. Electrochemical Behavior of Unusual Dimeric Flavonoids Isolated from Fridericia platyphylla
Brazil has the greatest plant diversity on the planet, distributed in different types of biomes. These plants are important sources of biologically active natural products, which are derived from various drugs marketed worldwide. This paper presents an electrochemical study of three unusual dimeric flavonoids, pharmacologically active, isolated and identifie
J. Braz. Chem. Soc.. Publicado em: 2021-06
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5. Gênero Cryptostegia: fitoquímica, atividades biológicas e aplicações industriais
The genus Cryptostegia comprises two species, C. madagascariensis (Bojer) and C. grandiflora (Roxb. Ex R. Br) that belong to the Apocynaceae family and are widely distributed in the tropics, as in Australia, New Zealand, India and Brazil, where they cause great socioeconomic and environmental damage, as they are invaders causing damage, mainly in the cultiva
Quím. Nova. Publicado em: 2021-06
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6. Premature birth: topics in physiology and pharmacological characteristics
SUMMARY OBJECTIVE: To review the main physiological and pharmacological changes related to prematurity, to promote the evidence-based clinical practice. METHODS: This is a narrative review whose research was carried out in the ScienceDirect and Medline databases via PubMed, searching for articles in any language from January 2000 to February 2020. RESULTS
Rev. Assoc. Med. Bras.. Publicado em: 2021-01
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7. The pharmacological interaction of compounds in ayahuasca: a systematic review
Ayahuasca is a South American psychoactive plant brew used as traditional medicine in spiritual and in cultural rituals. This is a review of the current understanding about the pharmacological mechanisms that may be interacting in ayahuasca. Searches were performed using PubMed, PsycINFO, and Web of Science databases and 16 papers were selected. As hypothesi
Braz. J. Psychiatry. Publicado em: 2020-12
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8. Treatment of iron overload syndrome: a general review
RESUMO INTRODUÇÃO A síndrome de sobrecarga de ferro engloba um grande espectro de etiologias que levam a um aumento da quantidade de ferro nos tecidos. Esse ferro excede a capacidade de proteção dos tecidos, levando a dano oxidativo e lesão tissular. Tratamento pode prevenir esse dano, levando à melhor sobrevida. METODOLOGIA A literatura dos últi
Rev. Assoc. Med. Bras.. Publicado em: 10/10/2019
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9. Sustainable production of bioactive alkaloids in Psychotria L. of southern Brazil: propagation and elicitation strategies
ABSTRACT Psychotria is the largest genus in Rubiaceae. South American species of the genus are promising sources of natural products, mostly due to bioactive monoterpene indole alkaloids they accumulate. These alkaloids can have analgesic, antimutagenic, and antioxidant activities in different experimental models, among other pharmacological properties of in
Acta Bot. Bras.. Publicado em: 07/10/2019
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10. Pharmacological evaluation of the hydro-alcoholic extract of Campomanesia phaea fruits in rats
Resumo Campomanesia phaea (Myrtaceae), popularmente conhecida como cambuci, é uma das várias espécies de plantas que produzem frutos comestíveis amplamente utilizados na nutrição humana. Apesar de seu consumo e potencial econômico, há poucas pesquisas científicas sobre a Campomanesia, especialmente aquelas relacionadas aos seus benefícios terapêut
Braz. J. Biol.. Publicado em: 07/10/2019
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11. Evidências científicas sobre métodos não farmacológicos para alívio a dor do parto
Resumo Objetivo Identificar na literatura nacional e internacional, estudos sobre a eficácia de métodos não farmacológicos na redução da dor do parto. Métodos Revisão integrativa realizada nas bases de dados MEDLINE/PUBMED, SCOPUS, CINAHL, LILACS e BDENF, com recorte temporal entre os anos de 2013 a 2018, em português, inglês e espanhol. Utiliz
Acta paul. enferm.. Publicado em: 29/07/2019
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12. Fears and beliefs of people living with rheumatoid arthritis: a systematic literature review
Abstract Objective: To assess the main fears and beliefs of people with rheumatoid arthritis (RA) and their effect on treatment outcomes; Methods: A systematic literature review was conducted in Pubmed/Medline; original articles published up to May 2017, reporting fears and/or beliefs of adult patients with RA were analyzed. Fears and beliefs were collecte
Adv. rheumatol.. Publicado em: 29/07/2019