Pharmaco
Mostrando 1-12 de 21 artigos, teses e dissertações.
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1. A prospective, randomized, single - blind study comparing intraplaque injection of thiocolchicine and verapamil in Peyronie's Disease: a pilot study
ABSTRACT Objectives: To compare the response to tiocolchicine and verapamil injection in the plaque of patients with Peyronie's disease. Materials and Methods: Prospective, single-blind, randomized study, selecting patients who have presented Peyronie's disease for less than 18 months. Thiocolchicine 4mg or verapamil 5mg were given in 7 injections (once a
Int. braz j urol.. Publicado em: 2016-10
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2. Brazilian plants with possible action on the Central Nervous System: a study of historical sources from the 16th to 19th century
Ethnopharmacological research when grounded on historic literature has for its objective retrieving traditional knowledge compiled throughout history by early cultures. The current study has used literature from the 16th to the 19th centuries to assess reports that include accounts of Brazil's native plants, with possible reports of disorders of the Central
Revista Brasileira de Farmacognosia. Publicado em: 25/03/2011
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3. Estudo da associação entre ansiedade e susceptibilidade à epilepsia do lobo temporal em ratos / Association between anxiety and susceptibility to temporal lobe epilepsy in rats
Subjects with temporal lobe epilepsy (TLE) present an heterogeneous response to pharmacotherapy. This heterogeneity results from physiological differences that might be caused by preexisting factors such as genetic ones. In many patients with TLE, the prognostic for controling the seizures is satisfactory. A significant proportion of individuals however do n
Publicado em: 2010
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4. Prevalência de sorotipos e resistência a antimicrobianos de cepas invasivas do Streptococcus pneumoniae em pacientes com diagnóstico de meningite admitidos em um hospital universitário
O objetivo deste trabalho foi avaliar o perfil dos sorotipos e a resistência a antimicrobianos de cepas de pneumococo obtidas a partir de espécimes clínicos de indivíduos admitidos com diagnóstico de meningite no Hospital de Clinicas da Universidade Federal de Uberlândia (HC-UFU). Cepas invasivas de pneumococo isoladas no Laboratório de Análises Clí
Publicado em: 2010
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5. Reversed phase HPLC determination of tamoxifen in dog plasma and its pharmaco-kinetics after a single oral dose administration
The analytical method developed to evaluate tamoxifen in dog plasma samples was precise, accurate, robust and linear in the range of 5-200 ng/mL. The limits of detection and quantification were 0.981 ng/mL and 2.97 ng/mL, respectively. Besides, the intra-day precision and accuracy variations were 8.78 and 10.16%, respectively. Tamoxifen concentrations were a
Química Nova. Publicado em: 2008
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6. Purificação e caracterização da beta-lapachona e estudo de estabilidade dos cristais em diferentes condições de armazenamento
The beta-lapachone is a product obtained from the Ipê Roxo tree [Tabebuia avellandae], which has proved its excellent antineoplasic potential acting through a particular mechanism of apoptosis against various cancer types. This study aims at determining the identity card of beta-lapachone by means of physico-chemical and pharmaco-technical characterization.
Química Nova. Publicado em: 2008
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7. Morphine pharmacokinetic-pharmacodynamic modeling administered by patient controlled analgesia (PCA) pump in the postoperative period of myocardial revascularization surgery / Modelagem farmacocinética-farmacodinâmica da morfina administrada através de bomba controlada pelo paciente no pós-operatório de revascularização do miocárdio
Introduction: Morphine administration using patient controlled analgesia (PCA) for treatment of post surgical and traumatic pain has been a current practice in many hospitals. However, large or repeated doses of this opioid are associated to dose dependent adverse events, including, respiratory depression. Considering patients submitted to thoracic surgery,
Publicado em: 2008
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8. Desenvolvimento, caracterizaÃÃo e estudo de permeaÃÃo cutÃnea de diclofenaco de dietilamÃnio em sistemas tÃpicos nanoemulsionados
The nanoemulsions (NE) are transparent, isotropic and thermodynamically stable systems, formed spontaneously under a specific set of experimental conditions from mixtures of water and oil phases stabilized by a surfactant or a mixture of surfactant and cosufactant. Because of their properties, especially the ability to carry lipophilic and hydrophilic drugs
Publicado em: 2008
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9. Intercalação de fármacos com atividade antiinflamatória (ácido mefenâmico e piroxicam) em hidróxido duplo lamelar / Intercalation of drugs with antiinflammatory activity (mefenamic acid and piroxicam) in layered double hydroxide
A intercalação de espécies de interesse biológico e terapêutico em Hidróxidos Duplos Lamelares (HDLs) vem se mostrando uma estratégia interessante para a obtenção de sistemas de armazenamento ou carregadores de drogas. No presente trabalho foram investigadas rotas sintéticas e parâmetros experimentais para a intercalação dos ânions derivados do
Publicado em: 2007
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10. Alterações lisossomais e indução de morte celular programada em celulas leucemicas tratadas com paladaciclo / Lysosomal alterations and programmed cell death induction in leukaemic cells treated with palladacycle
Experimental studies involving the pharmaco-toxicogical properties of new drugs are of very importance in its initial development (ERDAL et al., 2005). In this study it was evaluated the possible antileukemic effects of a new organometallic class of drugs called palladacycle ferrocene 1:2, using the K562 and Jurkat leukaemia cell lines. The cell death mechan
Publicado em: 2006
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11. The drug dispensation method implementation impact of Pharmacy-economic in kit on anesthetic and surgery procedure / Impacto farmacoeconômico da implantação do método de dispensação de drogas em forma de kit em procedimentos cirúrgicos e anestésicos
Purpose: The hospital a integrant of a health coordinated system, which duty is offer services. The hospital administratorsworry is get the lowest cost as possible and increasing the quality. As the hospital cost has an important installment represented by the medicine and materials consumed, and the pharmacy being the control responsible section, storage an
Publicado em: 2006
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12. Economic analyze about new drugs approved in Brazil between 1998 and 2001 / Análise econômica de novos fármacos licenciados no Brasil entre 1998 e 2001
O levantamento do número de medicamentos inovadores licenciados no Brasil pela agência reguladora de medicamentos durante quatro anos, entre 1998 e 2001, mostrou 154 medicamentos inovadores (fármacos com nova estrutura molecular). A maioria deles (57,1% do total) foi concentrada em quatro classes terapêuticas: quimioterapia sistêmica (39 produtos), anal
Publicado em: 2003