Pgl 1
Mostrando 1-12 de 78 artigos, teses e dissertações.
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1. Fatores associados à hanseníase em crianças contatos de adultos notificados em umaregião endêmica do Centro-Oeste do Brasil
Resumo Objetivos: Analisar os fatores associados à hanseníase em crianças contatos intradomiciliares de adultos notificados com a doença em município endêmico, Mato Grosso, Brasil. Método: Estudo caso-controle com 204 menores de 15 anos residentes em um município endêmico. Consideraram-se casos (n = 40) crianças registradas com hanseníase no Sis
J. Pediatr. (Rio J.). Publicado em: 2020-12
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2. Association between NDO-LID and PGL-1 for leprosy and class I and II human leukocyte antigen alleles in an indigenous community in Southwest Amazon
Abstract The frequencies of the Human leukocyte antigen (HLA) alleles in the Puyanawa indigenous reserve population and their association with the NDO-LID and ELISA PGL-1 rapid serological test was assessed. This was a cross-sectional study with an epidemiological clinical design conducted in two indigenous communities in the state of Acre, Brazil. Blood was
Braz J Infect Dis. Publicado em: 2020-08
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3. RAQUITISMO HIPOFOSFATÊMICO: RELATO DE CASO
RESUMO Objetivo: O raquitismo hipofosfatêmico precisa ser precocemente diagnosticado porque seu tratamento previne sequelas incapacitantes. Este relato alerta para a doença. Relato de caso: Relato de perfil metabólico, depuração de creatinina, estado nutricional e desenvolvimento pôndero-estatural de paciente com características clínico-laborator
Rev. paul. pediatr.. Publicado em: 29/03/2018
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4. RAQUITISMO HIPOFOSFATÊMICO: RELATO DE CASO
RESUMO Objetivo: O raquitismo hipofosfatêmico precisa ser precocemente diagnosticado porque seu tratamento previne sequelas incapacitantes. Este relato alerta para a doença. Relato de caso: Relato de perfil metabólico, depuração de creatinina, estado nutricional e desenvolvimento pôndero-estatural de paciente com características clínico-laborator
Rev. paul. pediatr.. Publicado em: 29/03/2018
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5. Evidence of hidden leprosy in a supposedly low endemic area of Brazil
OBJECTIVES Show that hidden endemic leprosy exists in a municipality of inner São Paulo state (Brazil) with active surveillance actions based on clinical and immunological evaluations. METHODS The study sample was composed by people randomly selected by a dermatologist during medical care in the public emergency department and by active surveillance carri
Mem. Inst. Oswaldo Cruz. Publicado em: 2017-12
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6. Salivary anti-PGL-1 IgM may indicate active transmission of Mycobacterium leprae among young people under 16 years of age
Abstract Considering that the main route of Mycobacterium leprae transmission is the upper respiratory tract, detection of salivary antibodies can be a useful tool for diagnosing early infection. The study aimed to analyze salivary anti-PGL-1 IgA and IgM antibodies in 169 children aged 4-16 years old, who lived nearby or inside the house of multibacillary or
Braz J Infect Dis. Publicado em: 2017-10
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7. Specific antigen serologic tests in leprosy: implications for epidemiological surveillance of leprosy cases and household contacts
BACKGROUND There is a lack of straightforward tests for field application and known biomarkers for predicting leprosy progression in infected individuals. OBJECTIVE The aim was to analyse the response to infection by Mycobacterium leprae based on the reactivity of specific antigens: natural disaccharide linked to human serum albumin via an octyl (NDOHSA)
Mem. Inst. Oswaldo Cruz. Publicado em: 2017-09
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8. Presence of Mycobacterium leprae genotype 4 in environmental waters in Northeast Brazil
Abstract INTRODUCTION: This study quantified Mycobacterium leprae bacilli in environmental water samples from five municipalities in the State of Ceará by quantitative polymerase chain reaction (qPCR) and compared the identified genotypes with those obtained from leprosy patient biopsies. METHODS: We collected five replicas from each of the 30 selected re
Rev. Soc. Bras. Med. Trop.. Publicado em: 2017-03
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9. Sunitinib in the therapy of malignant paragangliomas: report on the efficacy in a SDHB mutation carrier and review of the literature
SUMMARY Metastatic pheochromocytomas (PHEOs) and paragangliomas (sPGLs) are rare neural crest-derived tumors with a poor prognosis. About 50% of them are due to germ-line mutations of the SDHB gene. At present, there is no cure for these tumors. Their therapy is palliative and represented by different options among which antiangiogenic drugs, like sunitinib,
Arch. Endocrinol. Metab.. Publicado em: 10/10/2016
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10. Integrative literature review of the reported uses of serological tests in leprosy management
Abstract: An integrative literature review was conducted to synthesize available publications regarding the potential use of serological tests in leprosy programs. We searched the databases Literatura Latino-Americana e do Caribe em Ciências da Saúde, Índice Bibliográfico Espanhol em Ciências da Saúde, Acervo da Biblioteca da Organização Pan-American
Rev. Soc. Bras. Med. Trop.. Publicado em: 2016-04
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11. Risk-benefit assessment of Bacillus Calmette-Guérin vaccination, anti-phenolic glycolipid I serology, and Mitsuda test response: 10-year follow-up of household contacts of leprosy patients
Abstract: INTRODUCTION: Despite multidrug therapy, leprosy remains a public health issue. The intradermal Bacillus Calmette-Guérin (BCG) vaccine, Mitsuda test (lepromin skin test), and anti-phenolic glycolipid I (PGL-I) serology are widely used in leprosy studies and have shown great epidemiological value. METHODS: This longitudinal study evaluated the
Rev. Soc. Bras. Med. Trop.. Publicado em: 2015-12
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12. Multibacillary leprosy patients with high and persistent serum antibodies to leprosy IDRI diagnostic-1/LID-1: higher susceptibility to develop type 2 reactions
Leprosy inflammatory episodes [type 1 (T1R) and type 2 (T2R) reactions] represent the major cause of irreversible nerve damage. Leprosy serology is known to be influenced by the patient’s bacterial index (BI) with higher positivity in multibacillary patients (MB) and specific multidrug therapy (MDT) reduces antibody production. This study evaluated by ELIS
Mem. Inst. Oswaldo Cruz. Publicado em: 2015-11