Pge2 Receptors
Mostrando 1-12 de 76 artigos, teses e dissertações.
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1. Periapical bone response to bacterial lipopolysaccharide is shifted upon cyclooxygenase blockage
Abstract Objectives: Infection, inflammation and bone resorption are closely related events in apical periodontitis development. Therefore, we sought to investigate the role of cyclooxygenase (COX) in osteoclastogenesis and bone metabolism signaling in periapical bone tissue after bacterial lipopolysaccharide (LPS) inoculation into root canals. Methodology
J. Appl. Oral Sci.. Publicado em: 03/06/2019
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2. Participation of cannabinoid receptors in peripheral nociception induced by some NSAIDs
Nonsteroidal anti-inflammatory drugs (NSAIDs) have been used extensively to control inflammatory pain. Several peripheral antinociceptive mechanisms have been described, such as opioid system and NO/cGMP/KATP pathway activation. There is evidence that the cannabinoid system can also contribute to the in vivo pharmacological effects of ibuprofen and indometha
Braz J Med Biol Res. Publicado em: 2012-12
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3. Evaluation of expression and activation of opioid receptors after peripheral injury in rats. / Avaliação da expressão e ativação de receptores opióides após injúria periférica em ratos.
Este trabalho teve como objetivo avaliar os mecanismos envolvidos no aumento da eficácia analgesia da crotalfina (CRF), um peptídeo com atividade tipo opióide, na vigência de inflamação (prostaglandina E2/PGE2) ou lesão tecidual (constrição crônica do nervo isquiático/CCI). A PGE2 (intraplantar), em ratos, aumentou a expressão gênica e protéica
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 06/07/2011
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4. Participação da Prostaglandina E2 e seus receptores na proliferação celular do carcinoma epidermóide de cabeça e pescoço / Role of Prostaglandin E2 and its receptors in head and neck squamous cell carcinoma.
O carcinoma epidermóide de cabeça e pescoço (CECP) representa 6ª malignidade mais comum no mundo. Para melhor entender os mecanismos envolvidos na iniciação tumoral, progressão e metástase, é necessária a elucidação dos eventos moleculares que guiam esses processos. É também importante a investigação da interação e modulação das células
Publicado em: 2010
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5. Effect of soluble factors produced by TLR-activated macrophages on T lymphocytes survival. / Influência da ativação de macrófagos via receptores do tipo Toll (TLRs) na produção de fatores moduladores da sobrevivência de linfócitos T.
The interaction between innate and adaptative immunity occurs in several phases of the immune response. The Toll-like receptors (TLRs) have an important role in the activation of macrophages directly acting on the molecules secreted by these cells. Little is known about the role of these secreted molecules on the survival control of activated T lymphocytes (
Publicado em: 2010
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6. Papel dos receptores do tipo Toll na morte celular induzida por ativação (AICD) de linfócitos T. / Role of Toll-Like receptors in the activation-induced cell death (AICD) of T cells hybridoma.
During an infection the number of T lymphocytes increases dramatically. The clonal expansion phase is followed by reducing the level of activated T cells that depends, in part, a process of cell death induced by activation (AICD). Our group showed that when APCs are stimulated with LPS, a TLR4 agonist, produce PGE2, which inhibits the AICD of CD4 + T cells b
Publicado em: 2009
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7. Regulação do CD95L por PGE2 e seu impacto na morte de linfócitos T. / CD95L downregulation by PGE2 and its impact on T lymphocyte death.
Antigen-presenting cells (APCs) control T-cell responses by multiple mechanisms, including the expression of co-stimulatory molecules and the production of cytokines and other mediators that control T-cell proliferation, survival and differentiation. In this present work, it was demonstrated that soluble factor(s) produced by Toll-like receptor (TLR)-activat
Publicado em: 2008
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8. Emprego tópico de prostaglandina da família E ou de análogo com o intuito de acelerar a migração de embriões eqüinos para o útero e imunolocalização dos respectivos receptores / Topic application of prostaglandin E family or analogous aiming the acceleration of the migration of equine embryos to the uterus and immunolocalization of the respective receptors
Differently of any other ways of occurrence among the domestic animals, concerning mares, their embryos migrate in a delayed lapse of time to their uterus due to a correlation to the PGE2. Consequently, one extracts embryos which are already into some more advanced phase of their development (blastocyst and expanded blastocyst) normally exceeding 300 microme
Publicado em: 2008
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9. Mecanismos envolvidos na ação hiperalgesica do ATP em ratos / Mechanisms for hyperalgesic actions of ATP
Recentes estudos demonstram que a ativado de receptores P2X3,2/3 pelo ATP endógeno contribui para a hiperalgesia inflamatória. Portanto, os objetivos desse trabalho foram: (1) Estudar o mecanismo pelo qual a ativa o dos receptores P2X3,2/3 pelo ATP endogeno contribui para a hiperalgesia mecânica induzida no modelo da inflamacça causada pela carragenina,
Publicado em: 2008
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10. Expressão de recptores do tipo Toll e dectina em monocitos e neutrofilos estimulados pelo Paracoccidioides brasiliensis / Expression of Toll-like receptos and dectin-1 in monocytes and neutrophils stimulated by Paracoccidioides brasiliensis
Paracoccidioidomycosis (PCM) is an endemic mycosis in Latin America caused by the dimorphic fungus Paracoccidioides brasiliensis. The pattern of the immune responses to P. brasiliensis determines the disease progression and clinical outcome. Innate immune response is mediated by phagocytic cells, such as macrophage and neutrophils, which ingest and kill inva
Publicado em: 2008
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11. PADRONIZAÇÃO E VALIDAÇÃO DE UM NOVO MODELO DE FEBRE INDUZIDA PELA INJEÇÃO INTRATECAL DE PROSTAGLANDINA E2 EM RATOS JOVENS / CHARACTERIZATION AND VALIDATION OF A NEW FEVER MODEL INDUCED BY THE INTRATHECAL INJECTION OF PROSTAGLANDIN E2 IN YOUNG RATS
The fever response, besides being part of host defense response to infection or inflammation, is associated with discomfort and anxiety and may constitute a risk for febrile seizures in children. Therefore, antipyretic therapy is routinely prescribed for febrile patients. The animal models of fever using the systemic injection of lipopolysaccharide (LPS) and
Publicado em: 2006
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12. Atividade antiulcerogenica da desidrocrotonina e do oleo essencial obtidos a partir das cascas de Croton cajucara Benth, uma planta da familia Euphorbiacear
Croton cajucara Benth. (sacaca) is a plant species growing in the Amazon region which is popularly used to treat disorders of the digestive tract. We investigated the antiulcerogenic activity and the mechanism of action of the major constituents of the bark of the plant, i.e., the essential oil and dehydrocrotonin (OHC, a sesquiterpene lactone present in lar
Publicado em: 1999