Osteosarcoma
Mostrando 1-12 de 253 artigos, teses e dissertações.
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1. A very rare mass mimicking paraganglioma in the parapharyngeal area: extraskeletal osteosarcoma
Brazilian Journal of Otorhinolaryngology. Publicado em: 2022
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2. COL6A3 promotes cellular malignancy of osteosarcoma by activating the PI3K/AKT pathway
RESUMO OBJETIVO Neste estudo, investigamos a função do COL6A3 na mobilidade celular e na via PI3K/AKT em osteossarcomas. METODOLOGIA A expressão relativa do COL6A3 foi obtida a partir de dados GEO em tecidos de osteossarcoma. O RNA de interferência (siRNA) foi utilizado para reduzir a expressão do COL6A3 nas células, e o teste de contagem de célul
Rev. Assoc. Med. Bras.. Publicado em: 2020-06
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3. Lung metastases at the initial diagnosis of high-grade osteosarcoma: prevalence, risk factors and prognostic factors. A large population-based cohort study
ABSTRACT BACKGROUND: Osteosarcoma is the most prevalent malignant bone tumor in children and adolescents. Lung metastases are associated with poor prognosis. OBJECTIVE: The aim here was to explore the prevalence of and risk and prognostic factors for lung metastases in high-grade osteosarcoma patients. DESIGN AND SETTING: Retrospective cohort study bas
Sao Paulo Med. J.. Publicado em: 13/01/2020
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4. Delays in the health care system for children, adolescents, and young adults with bone tumors in Brazil
RESUMO Objetivo: Identificar atrasos no sistema de saúde em crianças e adolescentes e adultos jovens (AAJ; até 29 anos) com osteossarcoma e sarcoma de Ewing com informações dos registros de câncer de base hospitalar do Brasil. Métodos: Os dados dos pacientes foram extraídos de 161 registros de câncer de base hospitalar brasileiros entre 2007 e 201
J. Pediatr. (Rio J.). Publicado em: 25/11/2019
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5. Effects of mindfulness-based stress reduction combined with music therapy on pain, anxiety, and sleep quality in patients with osteosarcoma
Objectives: To evaluate the effects of mindfulness-based stress reduction (MBSR) combined with music therapy (MT) on clinical symptoms in patients with osteosarcoma. Methods: Patients diagnosed with osteosarcoma were assessed for eligibility. A total of 101 patients were ultimately randomized into the intervention and control groups. Both groups received r
Braz. J. Psychiatry. Publicado em: 16/05/2019
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6. Incidence and mortality of bone cancer among children, adolescents and young adults of Brazil
OBJECTIVES: Bone cancers occur frequently in children, adolescents, and young adults aging 15 to 29 years. Osteosarcoma and Ewing sarcoma are the most frequent subtypes in this population. The aim of this study was to describe incidence and mortality trends of bone cancers among Brazilian children, adolescents and young adults. METHODS: Incidence informati
Clinics. Publicado em: 13/05/2019
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7. Expressão de neurotrofinas e de seus receptores no osteossarcoma primário.
RESUMO Objetivo: determinar a expressão de neurotrofinas e seus receptores tirosina quinases em pacientes com osteossarcoma (OS) e sua correlação com desfechos clínicos. Métodos: biópsias de tumores primários de pacientes com OS tratados em uma única instituição, consecutivamente, entre 2002 e 2015, foram analisados através de imuno-histoquímic
Rev. Col. Bras. Cir.. Publicado em: 09/05/2019
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8. Osteosarcoma of the jaw – experience at the Medical University Vienna and comparative study with international tumor registries
OBJECTIVES: Osteosarcoma of the jaw (OSAJ) is fundamentally different in clinical practice from its peripheral counterparts. Studies are difficult to conduct due to low incidence rates. The primary aim of this study was to provide for the first time a comprehensive retrospective analysis of the treatment concepts and outcome data of OSAJ patients treated at
Clinics. Publicado em: 25/04/2019
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9. Astragalus polysaccharides decrease proliferation, migration, and invasion but increase apoptosis of human osteosarcoma cells by up-regulation of microRNA-133a
Osteosarcoma (OS) has a high incidence, malignity, and frequency of recurrence and metastasis. In this study, we aimed to explore the potential anti-cancer effects of Astragalus polysaccharides (APS) on human OS MG63 cells as well as underlying mechanisms. Viability of MG63 cells was assessed by CCK-8 assay to determine the adequate concentration of APS. The
Braz J Med Biol Res. Publicado em: 14/11/2018
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10. Chondroblastic osteosarcoma mimicking periapical abscess
Abstract Lesions of non-endodontic origin may mimic periapical abscess. Osteosarcoma is a rare malignant lesion. Case report The present report describes a case of chondroblastic osteosarcoma in the periapical region of teeth #29, #30, and #31 of an 18-year-old male. Clinical history showed self-reported discomfort in the right posterior gingiva for over a
J. Appl. Oral Sci.. Publicado em: 2017-08
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11. MicroRNA-340-5p modulates cisplatin resistance by targeting LPAATβ in osteosarcoma
MicroRNAs (miRNAs) play an important role in drug resistance and modulate the efficiency of chemotherapy. A recent study indicated that miR-340 functions as a tumor suppressor in various types of cancer. However, the role of miR-340 in chemotherapy has not been reported yet. In this study, we found that miR-340 enhanced cisplatin (CDDP)-induced cell death. I
Braz J Med Biol Res. Publicado em: 20/04/2017
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12. Investigating ego modules and pathways in osteosarcoma by integrating the EgoNet algorithm and pathway analysis
Osteosarcoma (OS) is the most common primary bone malignancy, but current therapies are far from effective for all patients. A better understanding of the pathological mechanism of OS may help to achieve new treatments for this tumor. Hence, the objective of this study was to investigate ego modules and pathways in OS utilizing EgoNet algorithm and pathway-r
Braz J Med Biol Res. Publicado em: 16/02/2017