Odontoblasts
Mostrando 13-24 de 32 artigos, teses e dissertações.
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13. Distribution of biglycan and decorin in rat dental tissue
Biglycan and decorin are small leucine-rich proteoglycans that play several biological and structural roles in different tissues and organs. Several reports have indicated that biglycan participates in odontoblast and ameloblast differentiation and in the calcification process. In the present study we show that the expression of biglycan changes from within
Brazilian Journal of Medical and Biological Research. Publicado em: 2003-08
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14. Estudo sobre o potencial imunogênico da dentina: contribuição para a etiopatogenia da reabsorção dentária / Study on the immunogenical dentin potencial: contribution for the etiopathogenesis of dental resorption
The dental resorptions are inflammatory and/or substitutive and represent the principal phenomenon that prevents the success of transplants and dental reimplants from happening. Its occurrence can be a consequence of traumatism, periapical disease and induced dental movements. During the odontogenesis the dentin is always "hidden" from immune system and late
Publicado em: 2001
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15. Endocytotic activity of kitten odontoblasts in early dentinogenesis. 1. Thin section and freeze-fracture study.
The morphological features of odontoblast processes in young kitten odontoblasts were studied by thin section and freeze-fracture electron microscopy. Freeze-fracture replication revealed depressions with particles on the plasma membranes of the proximal parts of odontoblast processes. Comparison with thin sections suggested that these depressions represente
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16. Nuclear Factor I-C Is Essential for Odontogenic Cell Proliferation and Odontoblast Differentiation during Tooth Root Development*
Our previous studies have demonstrated that nuclear factor I-C (NFI-C) null mice developed short molar roots that contain aberrant odontoblasts and abnormal dentin formation. Based on these findings, we performed studies to elucidate the function of NFI-C in odontoblasts. Initial studies demonstrated that aberrant odontoblasts become dissociated and trapped
American Society for Biochemistry and Molecular Biology.
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17. Disruption of Nfic Causes Dissociation of Odontoblasts by Interfering With the Formation of Intercellular Junctions and Aberrant Odontoblast Differentiation
We reported previously that Nfic-deficient mice exhibit short and abnormal molar roots and severely deformed incisors. The objective of this study is to address the mechanisms responsible for these changes using morphological, IHC, and RT-PCR analysis. Nfic-deficient mice exhibited aberrant odontoblasts and abnormal dentin formation in molar roots and the la
Histochemical Society.
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18. Disruption of Smad4 in Odontoblasts Causes Multiple Keratocystic Odontogenic Tumors and Tooth Malformation in Mice▿
Keratocystic odontogenic tumors (KCOTs) are cystic epithelial neoplasias with a high recurrence rate. However, the molecular mechanisms underlying the initiation and progression of KCOTs are still largely unknown. Here, we show that specific ablation of Smad4 in odontoblasts unexpectedly resulted in spontaneous KCOTs in mice. The mutant mice exhibited malfor
American Society for Microbiology (ASM).
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19. The fine structure of initial mineralisation during tooth development in the gummy shark, Mustelus manazo, Elasmobranchia.
In the enameloid matrix a large number of tubular vesicles appeared around the odontoblast processes at the stage of enameloid matrix formation. The tubular vesicles were limited by unit membrane and the membrane often seemed to connect with that of the odontoblast processes. The tubular vesicles probably originated from the odontoblasts. Electron-dense gran
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20. Is rabbit dentine innervated? A fine-structural study of the pulpal innervation in the cheek teeth of the rabbit.
The pulpal innervation of rabbit premolars and molars has been studied in transverse sections of perfusion-fixed, demineralised specimens using light microscopy and transmission electron microscopy. A mixed population of small myelinated and unmyelinated axons enters the apical foramen to supply the mesial and distal laminae of these continuously growing tee
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21. The time scale of tooth development and replacement in Xenopus laevis (Daudin).
One hundred and seventy two larval specimens of Xenopus laevis were reared in such a way that their rates of development (as measured by external criteria) were similar, and so the course of dental development could be examined histologically in a cross sectional study. In this way the events of tooth development were observed, and a time scale constructed f
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22. A fine structural study of coronal and root dentinogensis in the mouse: observations on the so-called 'von Korff fibres' and their contribution to mantle dentine.
The fine structure of mantle dentine formation has been studied in the mouse molar. No evidence was found for the presence of collagenous von Korff fibres arising from the dental papilla, passing between odontoblasts and fanning out to form the collagenous matrix of mantle detine. Instead, large collagen fibrils were first demonstrable in the matrix peripher
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23. Differentiation of embryonic mesenchymal cells to odontoblast-like cells by overexpression of dentin matrix protein 1
Cells of the craniofacial skeleton are derived from a common mesenchymal progenitor. The regulatory factors that control their differentiation into various cell lineages are unknown. To investigate the biological function of dentin matrix protein 1 (DMP1), an extracellular matrix gene involved in calcified tissue formation, stable transgenic cell lines
The National Academy of Sciences.
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24. Direct evidence of epithelial-mesenchymal interdependence in situ.
In the basal odontogenic zone of the mandibular incisor of the rat the cytological evidence of the toxicity of 40 mg cyclophosphamide per kg, 24 hours following a single intraperitoneal injection, was confined to the proliferating mesenchyme. Localised loss of precursors of odontoblasts cessation of basal odontogenesis and acellularity of the related part of