Occludin
Mostrando 1-12 de 57 artigos, teses e dissertações.
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1. Linderae radix ethanol extract attenuates alcoholic liver injury via attenuating inflammation and regulating gut microbiota in rats
This study aimed to explore the influence of gut microbiota alterations induced by Linderae radix ethanol extract (LREE) on alcoholic liver disease (ALD) in rats and to study the anti-inflammatory effect of LREE on ALD through the lipopolysaccharide (LPS) toll-like receptor 4 (TLR4)-nuclear factor kappa B (NF-κB) pathway. ALD rat models were established by
Braz J Med Biol Res. Publicado em: 16/05/2019
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2. Hypoxia-induced hyperpermeability of rat glomerular endothelial cells involves HIF-2α mediated changes in the expression of occludin and ZO-1
This study aimed to investigate the role of hypoxia-inducible factor-2α (HIF-2α) in the expression of tight junction proteins and permeability alterations in rat glomerular endothelial cells (rGENCs) under hypoxia conditions. The expression level of HIF-2α and tight junction proteins (occludin and ZO-1) in rGENCs were examined following 5% oxygen density
Braz J Med Biol Res. Publicado em: 17/05/2018
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3. Effect of Oxidized Soybean Oils on Oxidative Status and Intestinal Barrier Function in Broiler Chickens
ABSTRACT The objective of this study was to evaluate the effect of oxidized soybean oils on the growth performance, metabolic oxidative status and intestinal barrier function of broiler chickens. A total of 240 one-day-old female broiler chickens were assigned to four dietary treatments with six replicates (cages) of 10 birds each. The dietary treatments com
Braz. J. Poult. Sci.. Publicado em: 2018-04
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4. Claudin-3 and occludin content in the glands of colonic mucosa devoid from fecal stream submitted to topical intervention with oil extract of Curcuma longa
Abstract Purpose: To evaluate the inflammatory intensity and measure the tissue content of the proteins claudin-3 and occludin in the colonic mucosa without fecal stream submit to intervention with curcumin. Methods: Thirty-six rats were submitted to a proximal colostomy and a distal mucous fistula and divided into two groups according to sacrifice to be p
Acta Cir. Bras.. Publicado em: 2017-01
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5. Impact of acute undernutrition on growth, ileal morphology and nutrient transport in a murine model
Undernutrition represents a major public health challenge for middle- and low-income countries. This study aimed to evaluate whether a multideficient Northeast Brazil regional basic diet (RBD) induces acute morphological and functional changes in the ileum of mice. Swiss mice (∼25 g) were allocated into two groups: i) control mice were fed a standard diet
Braz J Med Biol Res. Publicado em: 10/10/2016
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6. Tumor necrosis factor alpha increases epithelial barrier permeability by disrupting tight junctions in Caco-2 cells
The objectives of this study were to determine the effect of tumor necrosis factor alpha (TNF-α) on intestinal epithelial cell permeability and the expression of tight junction proteins. Caco-2 cells were plated onto Transwell® microporous filters and treated with TNF-α (10 or 100 ng/mL) for 0, 4, 8, 16, or 24 h. The transepithelial electrical resistance
Brazilian Journal of Medical and Biological Research. Publicado em: 2010-04
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7. Lesões de isquemia arteriovenosa e reperfusão em jejuno de equinos: imunoistoquímica de proteínas de junção e histopatologia
To evaluate whether complete arteriovenous ischemia followed by reperfusion of mesenteric blood flow aggravates lesions involving small intestine of horses, β--catenin and occludin expressions were measured in jejune epithelia of seven equines, without definite breed. The animals had been submitted to aseptic ventral midline celiotomy and five jejune se
Publicado em: 2007
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8. Lesões de isquemia arteriovenosa e reperfusão em jejuno de equinos: imunoistoquímica de proteínas de junção e histopatologia
To evaluate whether complete arteriovenous ischemia followed by reperfusion of mesenteric blood flow aggravates lesions involving small intestine of horses, β--catenin and occludin expressions were measured in jejune epithelia of seven equines, without definite breed. The animals had been submitted to aseptic ventral midline celiotomy and five jejune se
Publicado em: 2007
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9. Schistosomal granuloma as a system adaptive complex. Application of fractal dimension in characterization of their geometric properties. / Granuloma esquistossomótico como um sistema adaptativo complexo. Aplicação da dimensão fractal na caracterização de suas propriedades geométricas.
Schistosomal granuloma AS A COMPLEX ADAPTIVE SYSTEM: APPLICATION OF FRACTAL DIMENSION IN THE CHARACTERIZATION OF PROPERTIES GEOMETRIC. Waldemiro de Souza Romagna. [Introduction]. The schistosomal granuloma is a compact, organized collection of migrating cells, which along with cells of the affected organ, arrange themselves in the midst of extracellular matr
Publicado em: 2007
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10. Four whole-istic aspects of schistosome granuloma biology: fractal arrangement, internal regulation, autopoietic component and closure
This paper centers on some whole-istic organizational and functional aspects of hepatic Schistosoma mansoni granuloma, which is an extremely complex system. First, it structurally develops a collagenic topology, originated bidirectionally from an inward and outward assembly of growth units. Inward growth appears to be originated from myofibroblasts derived f
Memórias do Instituto Oswaldo Cruz. Publicado em: 2006-10
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11. Occludin 1B, a Variant of the Tight Junction Protein Occludin
Occludin and claudin are the major integral membrane components of the mammalian tight junction. Although more than 11 distinct claudins have been identified, only 1 occludin transcript has been reported thus far. Therefore, we searched by reverse transcription–PCR for occludin-related sequences in Madin–Darby canine kidney (MDCK) mRNA and identified a t
The American Society for Cell Biology.
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12. Complex Phenotype of Mice Lacking Occludin, a Component of Tight Junction Strands
Occludin is an integral membrane protein with four transmembrane domains that is exclusively localized at tight junction (TJ) strands. Here, we describe the generation and analysis of mice carrying a null mutation in the occludin gene. Occludin −/− mice were born with no gross phenotype in the expected Mendelian ratios, but they showed significant p
The American Society for Cell Biology.