Nucleotides
Mostrando 25-36 de 8424 artigos, teses e dissertações.
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25. Phylogenetic study of Class Armophorea (Alveolata, Ciliophora) based on 18S-rDNA data
The 18S rDNA phylogeny of Class Armophorea, a group of anaerobic ciliates, is proposed based on an analysis of 44 sequences (out of 195) retrieved from the NCBI/GenBank database. Emphasis was placed on the use of two nucleotide alignment criteria that involved variation in the gap-opening and gap-extension parameters and the use of rRNA secondary structure t
Genet. Mol. Biol.. Publicado em: 2013
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26. Estudos estruturais e funcionais da Hsp90 de Leishmania braziliensis e suas co-chaperonas p23 / Structural and functional studies of Leishmania braziliensis Hsp90 and its p23 co-chaperones
Molecular chaperones are proteins involved in proper folding of other proteins, and others important cellular functions, why they have been targeted for combating various diseases. The Hsp90 (82-96 kDa) are ubiquitous chaperones that interact with a wide range of client proteins. They are formed by three domains: N-terminal, central or middle (M), and C-term
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 15/06/2012
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27. Vias intracelulares da ação do Sildenafil no diabetes insipidus induzido pelo lítio / Sildenafil action in lithium-induced NDI: intracellular pathway
Patients taking lithium to treat bipolar disorder often present polyuria and urinary concentrating defect. In addition, lithium-treated animals present lower cyclic adenosine monophosphate production in response to vasopressin. Sildenafil (Sil), a phosphodiesterase 5 (PDE5) inhibitor, elevates intracellular cyclic guanosine monophosphate (cGMP) levels, leadi
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 13/06/2012
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28. Desenvolvimento de um modelo para construção de mapas genéticos em autopoliploides, com aplicações em cana-de-açúcar / Development of a model to build genetic maps in autopolyploides, with applications in sugarcane
Autopolyploid species are extremely important in agriculture. However, the complex structure of their genomes is not well understood. Despite all advances in genetic mapping of autotetraploids, the vast majority of the models used for autopolyploid species with high ploidy level, such as sugarcane, are approximations of those used in diploid organisms. Thus,
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 29/05/2012
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29. Resposta de genótipos de citros à leprose e variabilidade genética da ORF p29 do vírus da leprose dos citros C (CiLV-C) / Response of citrus genotypes to leprosis and genetic variability of ORF p29 from Citrus leprosis virus C (CiLV-C)
Viruses have, potentially, broad genetic variability because of their need to adapt to several changes that they are exposed to. Therefore, genetic variability is essential for their survival; it is the first step to adapt to a new host, to break resistance down, to change symptoms and virulence, which justifies the interest in studies in this area. These st
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 16/05/2012
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30. Modelo de regulação dos nucleotídeos extracelulares no líquido superficial das vias respiratórias
Extracellular nucleotides play a key role in the regulation of mucociliary clearance and thus are essential in protecting the airways against inhaled pathogens. Adenosine triphosphate (ATP), adenosine diphosphate (ADP) and adenosine monophosphate (AMP) nucleotides are secreted by the respiratory epithelium to the airway surface liquid, where they are metabol
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 09/03/2012
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31. Avaliação do modelo de hiperargininemia sobre parâmetros neuroquímicos, moleculares e compartamentais em peixe-zebra (Danio rerio): uma abordagem sobre o sistema purinérgico
Hyperargininemia is a rare disease caused by an innate error of the metabolism (EIM) biochemically characterized by the accumulation of arginine in body tissues due to arginase deficits. Mental retardation and other neurological symptoms are common in hyperargininemic patients. Several mechanisms have been proposed to describe the neurotoxicity of hiperargin
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 02/03/2012
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32. Avaliação do valor de predição de clivagem química de radicais hidroxila em regiões promotoras de genes ligados ao desenvolvimento craniofacial / Evaluation of predictive value for chemical cleavage of hydroxy radicals in the promoter regions of genes related to craniofacial developmentl
The initiation of the gene transcription is a very complex phenomenon, probably the principal stage where the control of the gene expression takes place. In general terms the transcription takes place with the connection of proteins called "transcription factors" with specific sequences of the DNA, called of regions or sequences "cis ". The interaction DNA -
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 28/02/2012
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33. Participação dos canais de potássio no efeito relaxante do ácido ent-7a-hidroxitraquiloban-18-oico em traqueia isolada de cobaia / Participation of potassium channels in the ent-7a-hidroxitrachyloban-18-oic acid relaxation effect on guinea pig trachea
From Xylopia langsdorfiana A. St-Hil. &Tul. stem bark was isolated the diterpene of trachylobane class, ent-7α-hydroxytrachyloban-18-oic acid (trachylobane-318) that in previous studies showed to be able to relax guinea-pig trachea pre-contracted by carbachol (CCh). Thus, we aimed to investigate the action mechanism underlying in this trachylobane-318 r
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 17/02/2012
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34. Desmodus rotundus and Artibeus spp. bats might present distinct rabies virus lineages
In Brazil, bats have been assigned an increasing importance in public health as they are important rabies reservoirs. Phylogenetic studies have shown that rabies virus (RABV) strains from frugivorous bats Artibeus spp. are closely associated to those from the vampire bat Desmodus rotundus, but little is known about the molecular diversity of RABV in Artibeus
Braz J Infect Dis. Publicado em: 2012-12
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35. Identification of RAPD and SCAR markers associated with yield traits in the Indian tropical tasar silkworm Antheraea mylitta drury
The tropical tasar silkworm, Antheraea mylitta, is a semi-domesticated vanya silk-producing insect of high economic importance. To date, no molecular marker associated with cocoon and shell weights has been identified in this species. In this report, we identified a randomly amplified polymorphic DNA (RAPD) marker and examined its inheritance, and also devel
Genet. Mol. Biol.. Publicado em: 02/10/2012
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36. Cloning, bioinformatics analysis, and expression of the dust mite allergen Der f 5 of Dermatophagoides farinae
Crude extracts of house dust mites are used clinically for diagnosis and immunotherapy of allergic diseases, including bronchial asthma, perennial rhinitis, and atopic dermatitis. However, crude extracts are complexes with non-allergenic antigens and lack effective concentrations of important allergens, resulting in several side effects. Dermatophagoides far
Brazilian Journal of Medical and Biological Research. Publicado em: 2012-08