Neuroleptic
Mostrando 1-12 de 110 artigos, teses e dissertações.
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1. Prolapso retal em pequenos ruminantes: etiologia, técnicas anestésicas e cirúrgicas e evolução clínica em 12 animais - relato de caso
RESUMO Este relato descreve o prolapso retal de grau II intermitente ou permanente em nove ovinos e três caprinos. Para se estabelecer e tratar a causa primária, o histórico clínico foi minuciosamente explorado, sendo complementado pelo atendimento a campo. Nos pacientes predominou sobrepeso e tosse devido à pneumonia e, em menor proporção, verminose
Arq. Bras. Med. Vet. Zootec.. Publicado em: 28/10/2019
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2. ESTUDO PSICOFARMACOLÓGICO DO EXTRATO BRUTO DAS CASCAS DE Himatanthus drasticus MART / PSYCHOPHARMACOLOGY STUDY OF CRUDE EXTRACT OF PEEL Himatanthus drasticus MART.
Himatanthus drasticus Mart. popularmente conhecida como janaúba, é amplamente utilizada de forma medicinal como antitumoral, antiulcerogênica e analgésica. Estudos farmacológicos anteriormente realizados constataram ação antiulcerogênica, antiinflamatória, analgésica e antitumoral do extrato bruto e compostos isolados da espécie. Este trabalho inv
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 31/10/2011
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3. Dose-related effects of propericiazine in rats
We evaluated the effects of the neuroleptic agent propericiazine on animal models of anxiety and memory. Adult male Wistar rats (250 to 350 g) received intraperitoneal injections of propericiazine (0.05, 0.075 and 0.1 mg/kg), diazepam (1 mg/kg), saline, or diazepam vehicle (20% propylene glycol and 80% saline) 30 min prior to the experimental procedure. Anim
Publicado em: 2010
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4. INFLUÊNCIA DO ÔMEGA 3 SOBRE SINTOMAS EXTRAPIRAMIDAIS, DEFICIÊNCIA COGNITIVA E PARÂMETROS DE ESTRESSE OXIDATIVO EM ANIMAIS TRATADOS COM NEUROLÉPTICOS
Haloperidol and fluphenazine are typical neuroleptics widely used in the treatment of mental illness, whose chronic use is associated with adverse effects that affect the motor function and memory, among others. The motor disturbances can be moderate, and include parkinsonism, akathisia, dystonia, but also a more severe syndrome, known as tardive dyskinesia
Publicado em: 2009
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5. O EFEITO DO USO CRÔNICO DE HALOPERIDOL ASSOCIADO À DIETA COM ALTO TEOR DE LIPÍDIO NA PEROXIDAÇÃO LIPÍDICA NO FÍGADO DE RATOS WISTAR / THE EFFECT OF LONG TERM HALOPERIDOL USE ASSOCIATED TO HIGH FAT DIET ON THE LIPID PEROXIDATION IN WISTAR RAT LIVER
There is a growing number of evidences, associating the oxidative stress produced by the reactive species of oxygen, with the aging process at one hand, and with the beginning and development of the vascular complications of several chronic and degenerative diseases at another. The type of diet and the usage of specific medicines may be related among the res
Publicado em: 2007
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6. Estudo genético da doença de Parkinson / Genetical study of Parkinsons disease
Parkinson disease (PD) is the second most common neurodegenerative disorder affecting approximately 3% of the population over age 64. Most cases of PD manifest in sporadic form, but familial primary parkinsonism (PP) due to specific genetical abnormalities has been found in about 10% of cases diagnosed as PD. The aims of this study were to analyze the DNA of
Publicado em: 2007
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7. Acute effects of selective serotonin reuptake inhibitors on neuroleptic-induced catalepsy in mice
Depression found in Parkinson disease (PD) usually responds to selective serotonin reuptake inhibitors (SSRIs). Drugs that modify experimental neuroleptic catalepsy (NC) might affect extrapyramidal symptoms in PD. Therefore, the effects of SSRIs on NC were tested in mice, 26-36 g, separated by sex. Catalepsy was induced with haloperidol (H; 1 mg/kg, ip) and
Brazilian Journal of Medical and Biological Research. Publicado em: 2005-12
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8. Ação de drogas agonistas e antagonistas dos sistemas colinérgico e dopaminégico: estudo comportamental e neuroquímico em corpo estriado de rato. / The action of the agonists and antagonists drugs of cholinergic and dopaminergic systems: behavioral and neurochemical study in striatum of rats
In the study, the interaction between the dopaminergic and cholinergic systems through the study of behavioral (open field and catalepsy) and neurochemical (density of dopaminergic receptor (D1 and D2-like) and muscarinic (M1+M2-like)) effect in striatum rat was evaluated. The following drugs were used: mazindol (indirect dopaminergic agonist), apomorphine (
Publicado em: 2005
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9. Expression in normals and in subjects with schizophrenia of a novel gene fragment originally isolated from monozygotic twins discordant for schizophrenia
Differentially expressed clones from subtracted cDNA libraries of a pair of monozygotic twins discordant for schizophrenia have been reported in the literature. The clones were expressed in lymphocytes from the healthy twin, but not from the schizophrenic twin. In the current study, we assessed the expression of one of these clones, oksc12b, in 10 normal con
Genetics and Molecular Biology. Publicado em: 2004
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10. Gender-related differences in the effects of nitric oxide donors on neuroleptic-induced catalepsy in mice
It has been suggested that nigrostriatal dopaminergic transmission is modulated by nitric oxide (NO). Since there is evidence that gonadal hormones can affect extrapyramidal motor behavior in mammals, we investigated the effects of isosorbide dinitrate (ISD), linsidomine (SIN-1) and S-nitroso-N-acetylpenicillamine (SNAP), three pharmacologically different NO
Brazilian Journal of Medical and Biological Research. Publicado em: 2003-02
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11. Dose-related effects of propericiazine in rats
We evaluated the effects of the neuroleptic agent propericiazine on animal models of anxiety and memory. Adult male Wistar rats (250 to 350 g) received intraperitoneal injections of propericiazine (0.05, 0.075 and 0.1 mg/kg), diazepam (1 mg/kg), saline, or diazepam vehicle (20% propylene glycol and 80% saline) 30 min prior to the experimental procedure. Anim
Brazilian Journal of Medical and Biological Research. Publicado em: 2003-02
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12. Neuroleptic-induced acute respiratory distress syndrome
CONTEXTO: Apresentamos um caso de síndrome neuroléptica maligna e de síndrome do desconforto respiratório do adulto relacionada ao uso do neuroléptico. Discutimos a possível relação clínica e as alterações de creatinino-quinase, relaxamento muscular e função respiratória. RELATO DE CASO: Paciente de 41 anos, homem, branco. Internado por otalgia
Sao Paulo Medical Journal. Publicado em: 2003