Neural Degeneration
Mostrando 1-12 de 54 artigos, teses e dissertações.
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1. Wobbly syndrome in an Africa pygmy hedgehog (Atelerix albiventris): neuropathological and immunohistochemical studies
RESUMO: Um ouriço pigmeu africano de três anos de idade, nascido e domiciliado no Brasil, apresentou apatia, prostração e dificuldade em permanecer em estação. Os pais deste ouriço eram irmãos, mas não apresentaram sinais clínicos relacionados a esta condição. Com a piora dos sinais clínicos, o animal foi eutanasiado e encaminhado para necropsia
Cienc. Rural. Publicado em: 31/01/2019
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2. Immunohistochemical analysis of the neural structures of the posterior cruciate ligament in osteoarthritis patients submitted to total knee arthroplasty: an analysis of thirty-four cases
OBJECTIVES: Many authors recommend posterior cruciate ligament-retaining arthroplasty with the intention to maintain the proprioception properties of this ligament. Preservation of the neuroreceptors and nervous fibers may be essential for retaining the proprioception function of the posterior cruciate ligament. The present study was thus developed to evalu
Clinics. Publicado em: 2015-02
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3. Estudo da expressão da miostatina em modelos murinos para doenças neuromusculares. / Myostatin expression in mouse models of neuromuscular diseases.
A proteína miostatina, é um regulador negativo do crescimento muscular e a modulação de sua expressão pode consistir em tratamento para distrofias musculares. Nós estudamos expressão endógena da miostatina no músculos gastrocnêmio e diafragma de 4 modelos murinos de degeneração muscular: os camundongos Dmdmdx, SJL/J, Largemyd e Lama2dy-2J/J. Obse
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 21/03/2011
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4. DIFERENÇAS ENTRE IDOSOS BILÍNGUES E MONOLÍNGUES NO DESEMPENHO DE TAREFAS RELACIONADAS ÀS FUNÇÕES EXECUTIVAS, MEMÓRIA DE TRABALHO E MEMÓRIA EMOCIONAL DE LONGO PRAZO
Researches related to bilingualism and aging are recent. Regarding the increase of populations life expectation is a statistically proved fact, it is interesting to propose ideas that make people get older with a higher life quality. The aspect which may cause a higher life quality is the protection against the pathological aging, once several ways to protec
Publicado em: 2010
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5. Isolation and sequencing of the HMG domain of ten Sox genes from Odorrana schmackeri (Amphibia: Anura)
Sox (SRY-related HMG-box) genes encode a family of transcriptional regulators, which are characterized by a conserved 79-amino acid domain known as HMG-box. They play essential roles in a diverse range of processes including sex determination and the development of the central nervous system (CNS), neural crest and endoderm. In this paper, the HMG domain of
Zoologia (Curitiba). Publicado em: 2009-03
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6. Estudo da regeneração simpática pós simpaticotomia seletiva experimental (ramocotomia) / Study of sympathetic regeneration post experimental selective sympathicotomy (ramicotomy)
INTRODUCTION: Thoracic sympathectomy is the only definitive and efficient treatment for primary hyperhidrosis. The ramicotomy is a surgical procedure that is as efficient as conventional sympathectomy but more conservative, having less adverse effects then conventional sympathectomy. This procedure was abandoned on account of the high recurrence rate, attrib
Publicado em: 2009
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7. Comparative experimental study between fresh and predegenerated autografts in nerve reconstruction / "Estudo experimental comparativo entre auto-enxerto convencional e pré-degenerado na reconstrução de nervo"
Para avaliar a eficácia do método de pré-degeneração em nervos ciáticos de ratos durante diferentes intervalos de tempo, foram realizados estudos histomorfométricos de cortes laminares obtidos ao nível do enxerto e no segmento distal do nervo receptor. Os resultados foram comparados com a técnica convencional de enxertia nervosa. Verificou-se que o
Publicado em: 2006
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8. Multipotent neural precursors can differentiate toward replacement of neurons undergoing targeted apoptotic degeneration in adult mouse neocortex
Neurons undergoing targeted photolytic cell death degenerate by apoptosis. Clonal, multipotent neural precursor cells were transplanted into regions of adult mouse neocortex undergoing selective degeneration of layer II/III pyramidal neurons via targeted photolysis. These precursors integrated into the regions of selective neuronal death; 15 ± 7% differenti
The National Academy of Sciences of the USA.
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9. Degeneration of neurons, synapses, and neuropil and glial activation in a murine Atm knockout model of ataxia–telangiectasia
Neural degeneration is one of the clinical manifestations of ataxia–telangiectasia, a disorder caused by mutations in the Atm protein kinase gene. However, neural degeneration was not detected with general purpose light microscopic methods in previous studies using several different lines of mice with disrupted Atm genes. Here, we show electron microscopic
The National Academy of Sciences of the USA.
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10. Replication of the scrapie agent in ocular neural tissues.
Optic nerves and retinas removed from hamsters experimentally inoculated with the scrapie agent contain a high titer of infectivity. Ophthalmoscopic examination of these animals revealed gross lesions of retinopathy as early as 3 weeks before the onset of clinical signs of brain degeneration. These results suggest that the scrapie agent may spread centrifuga
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11. ω−3 Long-chain polyunsaturated fatty acid intake and 12-y incidence of neovascular age-related macular degeneration and central geographic atrophy: AREDS report 30, a prospective cohort study from the Age-Related Eye Disease Study1234
Background: ω−3 (n−3) Long-chain polyunsaturated fatty acids (LCPUFAs) affect processes implicated in vascular and neural retinal pathogenesis and thus may influence the risk of developing age-related macular degeneration (AMD).
American Society for Nutrition.
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12. Neurotoxin-induced degeneration of dopamine neurons in Caenorhabditis elegans
Parkinson's disease is a complex neurodegenerative disorder characterized by the death of brain dopamine neurons. In mammals, dopamine neuronal degeneration can be triggered through exposure to neurotoxins accumulated by the presynaptic dopamine transporter (DAT), including 6-hydroxydopamine (6-OHDA) and 1-methyl-4-phenylpyridinium. We have established a sys
The National Academy of Sciences.