Myosin Type Ii
Mostrando 1-12 de 79 artigos, teses e dissertações.
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1. Eccentric and concentric cardiac hypertrophy induced by exercise training: microRNAs and molecular determinants
Among the molecular, biochemical and cellular processes that orchestrate the development of the different phenotypes of cardiac hypertrophy in response to physiological stimuli or pathological insults, the specific contribution of exercise training has recently become appreciated. Physiological cardiac hypertrophy involves complex cardiac remodeling that occ
Brazilian Journal of Medical and Biological Research. Publicado em: 2011-09
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2. Characterization of the variety on cross sectional area, capillary density and neonatal myosin expression in the masseter and temporalis muscle / Caracterização da variação do calibre das fibras musculares, densidade capilar e expressão de miosina neonatal nos músculos masseter e temporal
Temporomandibular disfunction (TMD) is a colletive term that refers to different clinical problems of the temporomandibular joint and the jaw muscles. These disfunctions are characterizied meanly by pain, joint sounds and irregular or limited mandibular function. The jaw muscles can be involved in the TMD of muscle etiology, and by definition they are the on
Publicado em: 2009
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3. Muscle fiber type distribution and genotype correlation in the Pompe disease / Distribuição do tipo de fibras musculares e sua correlação genotípica na doença de Pompe
A doença de Pompe (GSDII), autossômica recessiva, é causada pela deficiência da enzima lisossomal que degrada o glicogênio, -glucosidase ácida (GAA). O quadro clínico varia de acordo com a idade de início da doença, grau de progressão e envolvimento dos tecidos: predominantemente cardíaco e muscular esquelético na forma de início-precoce (FIP) e
Publicado em: 2009
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4. Effect of salbutamol on innervated and denervated rat soleus muscle
The objective of the present investigation was to perform a 14-day time-course study of treatment with salbutamol, a ß2 adrenoceptor agonist, on rat soleus muscle in order to assess fiber type selectivity in the hypertrophic response and fiber type composition. Male Wistar rats were divided into four groups: control (N = 10), treated with salbutamol (N = 30
Brazilian Journal of Medical and Biological Research. Publicado em: 2005-12
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5. Analise fenotipica do musculo semitendinoso de ratos wistar e os efeitos do treinamento intervalado sobre suas fibras musculares
In general, the skeletal muscles are formed to several muscle fiber types that are able to express different kinds of myosin heavy chain (MHC) isoforms. The MHCI, IIa, IId and IIb will establish the pure muscle fibers of the type I, IIA, IID and IIB, respectively and, among them there are the hybrid fibers that can express two or more MHC types. In this work
Publicado em: 2004
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6. Regenerated rat skeletal muscle after periodic contusions
In the present study we evaluated the morphological aspect and changes in the area and incidence of muscle fiber types of long-term regenerated rat tibialis anterior (TA) muscle previously submitted to periodic contusions. Animals received eight consecutive traumas: one trauma per week, for eight weeks, and were evaluated one (N = 8) and four (N = 9) months
Brazilian Journal of Medical and Biological Research. Publicado em: 2001-11
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7. A Dictyostelium myosin II lacking a proximal 58-kDa portion of the tail is functional in vitro and in vivo.
We used molecular genetic approaches to delete 521 amino acid residues from the proximal portion of the Dictyostelium myosin II tail. The deletion encompasses approximately 40% of the tail, including the S2-LMM junction, a region that in muscle myosin II has been proposed to be important for contraction. The functions of the mutant myosin II are indistinguis
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8. Dictyostelium and Acanthamoeba myosin II assembly domains go to the cleavage furrow of Dictyostelium myosin II-null cells
How myosin II localizes to the cleavage furrow of dividing cells is largely unknown. We show here that a 283-residue protein, assembly domain (AD)1, corresponding to the AD in the tail of Dictyostelium myosin II assembles into bundles of long tubules when expressed in myosin II-null cells and localizes to the cleavage furrow of dividing cells. AD1 mutant
National Academy of Sciences.
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9. Novel Myosin Heavy Chain Kinase Involved in Disassembly of Myosin II Filaments and Efficient Cleavage in Mitotic Dictyostelium Cells
We have cloned a full-length cDNA encoding a novel myosin II heavy chain kinase (mhckC) from Dictyostelium. Like other members of the myosin heavy chain kinase family, the mhckC gene product, MHCK C, has a kinase domain in its N-terminal half and six WD repeats in the C-terminal half. GFP-MHCK C fusion protein localized to the cortex of interphase cells, to
The American Society for Cell Biology.
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10. Dictyostelium myosin II null mutant can still cap Con A receptors
Cross-linked antigens on the surface of a motile cell cap at the trailing end of the cell. In Dictyostelium discoideum, myosin II null mutants have previously been reported to be unable to cap Con A receptors, although they are able to locomote. This finding implicated myosin II as an essential component of the capping mechanism, although not of the machiner
The National Academy of Sciences of the USA.
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11. Chimeras of Dictyostelium myosin II head and neck domains with Acanthamoeba or chicken smooth muscle myosin II tail domain have greatly increased and unregulated actin-dependent MgATPase activity
Phosphorylation of the regulatory light chain of Dictyostelium myosin II increases Vmax of its actin-dependent MgATPase activity about 5-fold under normal assay conditions. Under these assay conditions, unphosphorylated chimeric myosins in which the tail domain of the Dictyostelium myosin II heavy chain is replaced by either the tail domain of chicken
The National Academy of Sciences.
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12. Myosin ATPase activity after strengthening exercise.
Alteration in the histochemical activity of myosin ATPase has been demonstrated in the soleus of adult rats after brief (A) and prolonged (B) intensive weight lifting exercises. The former represented 'high intensity-short duration' and the latter 'high intensity-prolonged duration' exercise. The data revealed a significant muscle hypertrophy (23-26%) in bot