Myosin Ii
Mostrando 1-12 de 225 artigos, teses e dissertações.
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1. YAP activation promotes the transdifferentiation of cardiac fibroblasts to myofibroblasts in matrix remodeling of dilated cardiomyopathy
Yes-associated protein (YAP) is an important regulator of cellular proliferation and transdifferentiation. However, little is known about the mechanisms underlying myofibroblast transdifferentiation in dilated cardiomyopathy (DCM). We investigated the role of YAP in the pathological process of cardiac matrix remodeling. A classic model of DCM was established
Braz J Med Biol Res. Publicado em: 23/11/2018
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2. Evaluation of different software tools for deconvolving differential scanning calorimetry thermograms of salted beef
Abstract The objective of this research was to evaluate the ability and efficiency of different software tools for the deconvolution of DSC thermograms of protein denaturation in salted beef. The salted samples were obtained by immersing beef pieces in NaCl solutions with concentrations of 20, 50, 100 and 330 g NaCl L-1 of water for 48 hours at 10 °C. The r
Food Sci. Technol. Publicado em: 17/11/2016
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3. Effect of hepatocyte growth factor and angiotensin II on rat cardiomyocyte hypertrophy
Angiotensin II (Ang II) plays an important role in cardiomyocyte hypertrophy. The combined effect of hepatocyte growth factor (HGF) and Ang II on cardiomyocytes is unknown. The present study was designed to determine the effect of HGF on cardiomyocyte hypertrophy and to explore the combined effect of HGF and Ang II on cardiomyocyte hypertrophy. Primary cardi
Braz J Med Biol Res. Publicado em: 2012-12
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4. Eccentric and concentric cardiac hypertrophy induced by exercise training: microRNAs and molecular determinants
Among the molecular, biochemical and cellular processes that orchestrate the development of the different phenotypes of cardiac hypertrophy in response to physiological stimuli or pathological insults, the specific contribution of exercise training has recently become appreciated. Physiological cardiac hypertrophy involves complex cardiac remodeling that occ
Brazilian Journal of Medical and Biological Research. Publicado em: 2011-09
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5. Characterization of the variety on cross sectional area, capillary density and neonatal myosin expression in the masseter and temporalis muscle / Caracterização da variação do calibre das fibras musculares, densidade capilar e expressão de miosina neonatal nos músculos masseter e temporal
Temporomandibular disfunction (TMD) is a colletive term that refers to different clinical problems of the temporomandibular joint and the jaw muscles. These disfunctions are characterizied meanly by pain, joint sounds and irregular or limited mandibular function. The jaw muscles can be involved in the TMD of muscle etiology, and by definition they are the on
Publicado em: 2009
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6. Muscle fiber type distribution and genotype correlation in the Pompe disease / Distribuição do tipo de fibras musculares e sua correlação genotípica na doença de Pompe
A doença de Pompe (GSDII), autossômica recessiva, é causada pela deficiência da enzima lisossomal que degrada o glicogênio, -glucosidase ácida (GAA). O quadro clínico varia de acordo com a idade de início da doença, grau de progressão e envolvimento dos tecidos: predominantemente cardíaco e muscular esquelético na forma de início-precoce (FIP) e
Publicado em: 2009
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7. Constrição celular apical durante a invaginação do placóide do cristalino em galinhas. / Apical cell constriction during chicken lens placode invagination.
O cristalino de vertebrados se origina a partir da invaginação do ectoderme que recobre a vesícula óptica. A invaginação epitelial em diversos modelos é causada pela constrição celular apical, mediada pela contração apical de actina e miosina II e regulada pela GTPase RhoA. Neste trabalho nós investigamos se a invaginação do cristalino em embri
Publicado em: 2008
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8. Expressão dos fatores de regulação miogenica e de cadeia pesada da miosina no musculo estriado esquelitico da tilapia do Nilo (Oreochromis niloticus) durante o crecimento / Miogenic regulatory factors and myosin heavy chain expression in the striated skeletal muscle of the Nile tilapia (Oreochromis niloticus) during growth
Nos peixes, o conhecimento dos fatores que controlam o crescimento muscular e a análise das proteínas miofibrilares, é importante para entender a dinâmica do crescimento, a plasticidade e as adaptações musculares, principalmente, em espécies com grande valor comercial como a tilápia do Nilo (Oreochromis niloticus). No presente estudo, utilizou-se a t
Publicado em: 2008
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9. Precipitação de actomiosina de vertebrados por congelamento de fração solúvel
RESUMO GERAL - Miosinas são proteínas motoras que translocam sobre filamentos de actina e atualmente constituem uma superfamília com 20 classes. Algumas são conhecidas apenas a estrutura primária através de seqüência gênica, outras já estão bem caracterizadas bioquimicamente, como as miosinas I, II e V. São amplamente distribuídas em todas as c�
Publicado em: 2006
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10. Effect of salbutamol on innervated and denervated rat soleus muscle
The objective of the present investigation was to perform a 14-day time-course study of treatment with salbutamol, a ß2 adrenoceptor agonist, on rat soleus muscle in order to assess fiber type selectivity in the hypertrophic response and fiber type composition. Male Wistar rats were divided into four groups: control (N = 10), treated with salbutamol (N = 30
Brazilian Journal of Medical and Biological Research. Publicado em: 2005-12
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11. Analise fenotipica do musculo semitendinoso de ratos wistar e os efeitos do treinamento intervalado sobre suas fibras musculares
In general, the skeletal muscles are formed to several muscle fiber types that are able to express different kinds of myosin heavy chain (MHC) isoforms. The MHCI, IIa, IId and IIb will establish the pure muscle fibers of the type I, IIA, IID and IIB, respectively and, among them there are the hybrid fibers that can express two or more MHC types. In this work
Publicado em: 2004
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12. Regenerated rat skeletal muscle after periodic contusions
In the present study we evaluated the morphological aspect and changes in the area and incidence of muscle fiber types of long-term regenerated rat tibialis anterior (TA) muscle previously submitted to periodic contusions. Animals received eight consecutive traumas: one trauma per week, for eight weeks, and were evaluated one (N = 8) and four (N = 9) months
Brazilian Journal of Medical and Biological Research. Publicado em: 2001-11