Myonecrosis
Mostrando 13-24 de 63 artigos, teses e dissertações.
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13. Development of a sensitive enzyme immunoassay (ELISA) for specific identification of Lachesis acrochorda venom
The snake genus Lachesis provokes 2 to 3% of snakebites in Colombia every year. Two Lachesis species, L. acrochorda and L. muta, share habitats with snakes from another genus, namely Bothrops asper and B. atrox. Lachesis venom causes systemic and local effects such as swelling, hemorrhaging, myonecrosis, hemostatic disorders and nephrotoxic symptoms similar
Journal of Venomous Animals and Toxins including Tropical Diseases. Publicado em: 2012
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14. Efeito do ácido eicosapentaenoico na necrose e inflamação dos músculos distróficos de camundongos mdx / Effects of eicosapentaenoic acid on myonecrosis and inflammation in dystrophin-deficient muscles of the mdx mice
Na distrofia muscular de Duchenne e no camundongo mdx a proteína distrofina está ausente ou é expressa de forma não funcional. Com isso, o complexo distrofina-glicoproteínas se desorganiza, a fibra muscular se torna frágil durante os ciclos de contração e relaxamento muscular, as concentrações intracelulares de cálcio e radicais livres se elevam,
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 15/12/2011
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15. Caracterização bioquímica e funcional de uma metaloprotease isolada da peçonha da serpente bothrops moojeni
CHAPTER II: Bothrops snake venoms contain proteins that contribute to the local and systemic effects seen after envenoming, such as edema, myonecrosis, coagulation disorders and hemorrhage. These effects can be triggered by the toxic action of metalloproteinases present in the bothropic venom. This study aimed to perform the purification, biochemical and fun
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 26/07/2011
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16. PURIFICAÇÃO DO VÍRUS DA MIONECROSE INFECCIOSA (IMNV) EM CAMARÃO MARINHO DA ESPÉCIE LITOPENAEUS VANNAMEI E DESENVOLVIMENTO DE TÉCNICAS SOROLÓGICAS PARA O SEU DIAGNÓSTICO. / PURIFICATION OF INFECTIOUS VIRUS myonecrosis (IMNV) MARINE SPECIES IN SHRIMP Litopenaeus vannamei AND DEVELOPMENT serological techniques FOR YOUR DIAGNOSIS
O objetivo deste estudo foi purificar e caracterizar o agente viral da mionecrose infecciosa (IMN), através de técnicas de baixo custo. Para tanto, foram utilizados camarões oriundos de duas carciniculturas no interior do Ceará, que apresentavam sintomas da mionecrose. As amostras foram estocadas a -20C, e encaminhadas para o Centro de Estudo e Diagnóst
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 18/07/2011
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17. Fibrose muscular em camundongo mdx : efeitos do exercício físico e de agente anti-fibrótico / : Prevention of muscle fibrosis and myonecrosis in mdx mice by suramin, a TGF-beta1 blocker
The mdx mouse is commonly used as a model to study Duchenne muscular dystrophy (DMD) however shows cycles of muscle regeneration and reduced fibrosis. The purposes of this study were (1) to induce muscle fibrosis through eccentric running exercise in mdx mice and (2) to verify the effects of suramin on muscle fibrosis. Six-month-old mdx (n=42) and control (C
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 18/02/2011
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18. Detection of infectious myonecrosis virus in penaeid shrimps using immunoassays: usefulness of monoclonal antibodies directed to the viral major capsid protein.
2011
Archives of Virology. Publicado em: 2011
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19. Detection of major capsid protein of infectious myonecrosis virus in shrimps using monoclonal antibodies.
Infectious myonecrosis virus (IMNV) has been causing a progressive disease in farm-reared shrimps in Brazil and Indonesia. Immunodiagnosticmethods for IMNVdetection, although reliable, are not employed currently becausemonoclonal antibodies (MAbs) against this virus are not available. In this study, a fragment of the IMNVmajor capsid protein gene, comprising
Journal of Virological Methods. Publicado em: 2011
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20. Biological characterization of a myotoxin phosphoplipase A2 homologue purified from the venom of the snake Bothrops moojeni
A myotoxin phospholipase A2 homologue, BmooMtx, was isolated from the venom of Bothrops moojeni by a combination of ion-exchange chromatography on DEAE-Sephacel column and gel filtration on Sephadex G-75. SDS-PAGE showed the enzyme to be a monomer with a molecular weight of 16,500. BmooMtx induced release of creatine kinase and morphological analyses indicat
Journal of Venomous Animals and Toxins including Tropical Diseases. Publicado em: 2011
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21. Effect of Bothrops alternatus snake venom on macrophage phagocytosis and superoxide production: participation of protein kinase C
Envenomations caused by different species of Bothrops snakes result in severe local tissue damage, hemorrhage, pain, myonecrosis, and inflammation with a significant leukocyte accumulation at the bite site. However, the activation state of leukocytes is still unclear. According to clinical cases and experimental work, the local effects observed in envenenoma
Journal of Venomous Animals and Toxins including Tropical Diseases. Publicado em: 2011
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22. Mediação da osteopontina na mionecrose e regeneração muscular após envenenamento por Bothrops lanceolatus / Osteopontin mediation on myonecrosis and muscle regeneration after Bothrops lanceolatus snake envenoming
Os acidentes por serpentes venenosas podem causar alterações locais graves e de rápido desenvolvimento. O veneno de Bothrops lanceolatus (VBL) contém, dentre outras toxinas, metaloproteinases hemorrágicas e pouco hemorrágicas (SVMPI e SVMPIII) e atividade pró-trombina que causam inflamação (vias das ciclooxigenases-COX e lipoxigenases), alterações
Publicado em: 2011
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23. Low-level laser therapy decreases local effects induced by myotoxins isolated from Bothrops jararacussu snake venom
The prominent myotoxic effects induced by Bothrops jararacussu crude venom are due, in part, to its polycationic myotoxins, BthTX-I and BthTX-II. Both myotoxins have a phospholipase A2 structure: BthTX-II is an active enzyme Asp-49 PLA2, while BthTX-I is a Lys-49 PLA2 devoid of enzymatic activity. In this study, the effect of low-level laser therapy (LLLT),
Journal of Venomous Animals and Toxins including Tropical Diseases. Publicado em: 2010
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24. Purification and functional characterization of a new non-hemorrhagic metalloprotease from Bothrops moojeni snake venom / Purificação e caracterização bioquímica da moozincina, uma metaloprotease dependente de zinco presente na peçonha da serpente Bothrops moojeni (Caiçaca)
Bothrops snake venoms contain proteases that contribute to the local effects seen after envenoming. In this study, a non-hemorrhagic metalloprotease was isolated from the venom of B. moojeni. The enzyme was isolated by a combination of ion exchange and gel filtration chromatographies and named Moozincin. The enzyme was purified to homogeneity as judged by it
Publicado em: 2010